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dc.contributor.authorOehme, Ninnie Helen Bakken
dc.contributor.authorRoelants, Mathieu
dc.contributor.authorBruserud, Ingvild Særvold
dc.contributor.authorMadsen, Andre
dc.contributor.authorBjerknes, Robert
dc.contributor.authorRosendahl, Karen
dc.contributor.authorJuliusson, Pétur Benedikt
dc.date.accessioned2021-07-08T11:14:22Z
dc.date.available2021-07-08T11:14:22Z
dc.date.issued2021-02-05
dc.description.abstractBackground - Previous studies investigating the association between weight status and onset of puberty in boys have been equivocal. It is currently unclear to what extent weight class influences puberty onset and progression.<p> <p>Objectives - To explore the relationship between degree of sexual maturation and anthropometric measures in Norwegian boys.<p> <p>Methods - The following endpoints were collected in a Norwegian cross-sectional study of 324 healthy boys aged 9–16: ultrasound-determined testicular volume (USTV), total serum testosterone, Tanner pubic hair stage, height, weight, waist circumference (WC), subscapular skinfolds (SSF), and body fat percentage (%BF). Testicular volume-for-age z-scores were used to classify “early,” “average,” or “late” maturing boys. Ordinal logistic regression analyses with a proportional odds model were applied to analyze the association between anthropometric variables and age-adjusted degree of pubertal development, with results expressed as age-adjusted odds ratios (AOR). Cumulative incidence curves for reaching pubertal milestones were stratified by BMI.<p> <p>Results - Boys with a low BMI for age (BMIz < −1) were less likely to have reached a pubertal testicular volume (USTV ≥ 2.7 mL) or a pubertal serum level of testosterone (≥0.5 nmol/L) compared to normal weight boys (AOR 0.3, p = 0.038, AOR 0.3, p = 0.026, respectively), and entered puberty on average with a delay of approximately eight months. Boys with high BMI for age (BMIz > 1) exhibited a comparable timing as normal weight boys. The same was found for WC. Pubertal markers were not associated with SSF or %BF.<p> <p>Conclusion - By examining the association between puberty and weight status classified as low, average, or high, we found that a low BMI or WC for age were associated with a less advanced pubertal development and delayed timing of puberty in boys. No significant association was observed for a high BMI or WC. Moreover, no significant effects of SSF or %BF were observed. A low weight status should also be considered when assessing pubertal development in boys.en_US
dc.identifier.citationOehme, Roelants, Bruserud, Madsen, Bjerknes, Rosendahl, Juliusson. Low BMI, but not high BMI, influences the timing of puberty in boys. Andrology. 2021:1-9
dc.identifier.cristinIDFRIDAID 1897651
dc.identifier.doi10.1111/andr.12985
dc.identifier.issn2047-2919
dc.identifier.issn2047-2927
dc.identifier.urihttps://hdl.handle.net/10037/21850
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.journalAndrology
dc.relation.projectIDHelse Vest RHF: 911975
dc.rights.holderCopyright 2021 The Author(s)en_US
dc.subjectVDP::Medical disciplines: 700::Basic medical, dental and veterinary science disciplines: 710en_US
dc.subjectVDP::Medisinske Fag: 700::Basale medisinske, odontologiske og veterinærmedisinske fag: 710en_US
dc.titleLow BMI, but not high BMI, influences the timing of puberty in boysen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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