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dc.contributor.authorElumalai, Vijayaragavan
dc.contributor.authorHansen, Jørn H
dc.date.accessioned2021-12-14T12:25:50Z
dc.date.available2021-12-14T12:25:50Z
dc.date.issued2021-11-16
dc.description.abstractThe synthesis of novel 5,7-diaryl and diheteroaryl indoles has been explored via efficient double Suzuki–Miyaura coupling. The method notably employs a low catalyst loading of Pd(PPh<sub>3</sub>)<sub>4</sub> (1.5 mol%/coupling) and water as the reaction solvent to obtain 5,7-diarylated indoles without using N-protecting groups in up to 91% yield. The approach is also suitable for N-protected and 3-substituted indoles and constitutes an important green and convenient arylation strategy for the benzenoid ring of indoles. The synthesized diarylindoles are fluorescent.en_US
dc.identifier.citationElumalai V, Hansen JHH. Synthesis of 5,7-diarylindoles via Suzuki-Miyaura coupling in water. Organic and biomolecular chemistry. 2021en_US
dc.identifier.cristinIDFRIDAID 1955861
dc.identifier.doi10.1039/D1OB02058G
dc.identifier.issn1477-0520
dc.identifier.issn1477-0539
dc.identifier.urihttps://hdl.handle.net/10037/23391
dc.language.isoengen_US
dc.relation.journalOrganic and biomolecular chemistry
dc.relation.projectIDinfo:eu-repo/grantAgreement/RCN/FRINATEK/275043/Norway/CasCat: Cascade Catalysis for Late-Stage C-H Functionalization/CasCat/en_US
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2021 The Author(s)en_US
dc.subjectVDP::Mathematics and natural science: 400::Chemistry: 440en_US
dc.subjectVDP::Matematikk og Naturvitenskap: 400::Kjemi: 440en_US
dc.titleSynthesis of 5,7-diarylindoles via Suzuki-Miyaura coupling in wateren_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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