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dc.contributor.authorGe, Pengfei
dc.contributor.authorDong, Caixia
dc.contributor.authorRen, Xiaolan
dc.contributor.authorWeiderpass, Elisabete
dc.contributor.authorZhang, Chouji
dc.contributor.authorFan, Haoqiang
dc.contributor.authorZhang, Jing
dc.contributor.authorZhang, Yongrui
dc.contributor.authorXi, Jinen
dc.date.accessioned2022-04-21T10:55:31Z
dc.date.available2022-04-21T10:55:31Z
dc.date.issued2015-12-07
dc.description.abstractBackground<p> <p>Dyslipidemia is a major health problem in China and an important modifiable cardiovascular disease (CVD) risk factor. This study aimed to describe the prevalence of dyslipidemia and low high density lipoprotein cholesterol (HDL-cholesterol) and associated risk factors among adults in rural northwest China.<p> Methods<p> <p>In a cross-sectional analyses involving 2,980 adults aged >18 years, information on the demographics, cigarette smoking, alcohol consumption, education, and medical history was collected via face-to-face interviews. Blood samples were collected to determine total cholesterol (TC), low-density lipoprotein cholesterol (LDL-cholesterol), and HDL-cholesterol, and triglycerides (TG) levels.<p> Results<p> <p>The prevalence of high TC, high LDL-cholesterol, low HDL-cholesterol, and high TG were 1.0%, 0.6%, 60.9%, and 13.7%, respectively. TC, LDL-cholesterol, and TG increased with age in females. Elevated TC was more common in females than in males. The prevalence of low HDL-cholesterol was 67.6% in males and 55.4% in females. Current smokers, those with less education, those who were overweight or obese, and those with large waist circumference were more likely to have low HDL-cholesterol (p<0.05). Multivariable regression showed that male gender showed an association with low HDL-cholesterol (OR 2.10, 95%CI 1.68–2.61), age ≥60 years (OR 0.80, 95% CI 0.64–0.99), BMI (BMI = 24–27.9, OR 1.27, 95%CI 1.04–1.54, p = 0.02 and BMI≥28, OR 1.56, 95%CI 1.10–2.20, p = 0.01) and enlarged waist circumference (OR 2.10, 95%CI 1.51–2.92). Non-alcohol drinker was associated with low HDL-cholesterol levels (OR 0.72, 95%CI 0.53–0.99, p = 0.04).<p> Conclusions<p> <p>This study found that the prevalence of low HDL-cholesterol was 67.6% and 55.4% for males and females. Male gender, non-alcohol drinker, BMI and central obesity were important risk factors for low HDL-cholesterol in Chinese adults.en_US
dc.identifier.citationGe, Dong, Ren, Weiderpass E, Zhang, Fan, Zhang J, Zhang, Xi. The high prevalence of low HDL-cholesterol levels and dyslipidemia in rural populations in Northwestern China. PLOS ONE. 2015;10:e0144104(12)
dc.identifier.cristinIDFRIDAID 1338227
dc.identifier.doi10.1371/journal.pone.0144104
dc.identifier.issn1932-6203
dc.identifier.urihttps://hdl.handle.net/10037/24838
dc.language.isoengen_US
dc.publisherPublic Library of Scienceen_US
dc.relation.journalPLOS ONE
dc.rights.holderCopyright 2015 The Author(s)en_US
dc.titleThe high prevalence of low HDL-cholesterol levels and dyslipidemia in rural populations in Northwestern Chinaen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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