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dc.contributor.authorHanno, Therese von
dc.contributor.authorSjølie, Anne Katrin
dc.contributor.authorMathiesen, Ellisiv B.
dc.date.accessioned2022-06-16T07:39:01Z
dc.date.available2022-06-16T07:39:01Z
dc.date.issued2013-07-04
dc.description.abstractPurpose: To investigate whether retinal vessel calibre measurements on optical retinal photography are affected by light and dark exposure prior to photography and whether the vessel calibre changes during an imaging sequence of several images. <p>Methods: Digital optical retinal photographs were obtained from 32 healthy adults in two separate image sequences of six images during 1 min; one sequence with 10 min of dark exposure and one with 10 min of light exposure prior to imaging. Retinal arteriolar and venular calibres were measured computer-assisted and summarized as central retinal artery and vein equivalents (CRAE and CRVE). Outcome measures were difference in calibres after prior light versus prior dark exposure and difference in calibre during each of the two imaging sequences. <p>Results: CRVE was wider with prior light exposure (2.7%, p = 0.0001), comparing the first image in each image sequence. Within each sequence, there was a venular dilatation from first to last image, both with prior light exposure (1.7%, p = 0.0003) and prior dark exposure (3.1%, p < 0.0001), with the change less pronounced with prior light exposure (p = 0.0164). CRAE showed no significant change in either outcome. <p>Conclusions: Retinal venular calibre was wider with light exposure prior to imaging and increased slightly during the imaging sequences, less pronounced after prior light than dark exposure. Measurement error due to these effects will probably be reduced by avoiding dark prior to imaging, and a possible bias effect of endothelial dysfunction may possibly be reduced by measuring calibre on an image taken early in the image sequence.en_US
dc.identifier.citationHanno T, Sjølie AK, Mathiesen EB. Retinal vascular calibre and response to light exposure and serial imaging. Acta Ophthalmologica. 2014;92(5):444-448en_US
dc.identifier.cristinIDFRIDAID 1086679
dc.identifier.doi10.1111/aos.12213
dc.identifier.issn1755-375X
dc.identifier.issn1755-3768
dc.identifier.urihttps://hdl.handle.net/10037/25486
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.journalActa Ophthalmologica
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2013 The Author(s)en_US
dc.titleRetinal vascular calibre and response to light exposure and serial imagingen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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