The risk factors for radial artery and saphenous vein graft occlusion are different
Permanent link
https://hdl.handle.net/10037/27490Date
2022-06-02Type
Journal articleTidsskriftartikkel
Peer reviewed
Author
Bahar, Ramez; Hermansen, Stig Eggen; Dahl-Eriksen, Øystein; Busund, Rolf; Dahl, Per Erling; Iqbal, Amjid; Mannsverk, Jan Torbjørn; Myrmel, Truls; Steigen, Terje; Trovik, Thor; Sørlie, Dag Glen; Bartnes, KristianAbstract
Objectives. To determine risk factors for radial artery and saphenous vein graft occlusion during long-term
follow-up after coronary artery bypass grafting (CABG). Methods: From a cohort of 119 patients who had
received a radial artery graft, 76 – of whom 55 also had at least one saphenous vein graft – underwent a
preplanned direct angiography and anthropometric, biochemical, and endothelial function assessment
7.6–12.1 (mean 8.9) years after CABG. Comorbidity, medication, and smoking habits were also recorded.
The association between these parameters and conduit longevity was analyzed in univariable and multivariable logistic regression models. Results: Radial artery graft occlusions were associated with higher
plasma levels of high-sensitive C-reactive protein and patency was best among patients with pharmacologically treated hypertension. The sole independent risk factor identified for saphenous vein graft occlusion was tobacco smoking 8–12 years postoperatively. Conclusion: Our data support the contention that
the pathogenesis of radial artery graft failure is distinct from vein graft disease and is related to hypertension status and systemic inflammation. These risk factors are potential targets for preventive measures.
Accordingly, the study supports the eventual design of personalized secondary prevention regimens.
Publisher
Taylor & FrancisCitation
Bahar, Hermansen, Dahl-Eriksen, Busund, Dahl, Iqbal, Mannsverk, Myrmel, Steigen, Trovik, Sørlie, Bartnes. The risk factors for radial artery and saphenous vein graft occlusion are different. Scandinavian Cardiovascular Journal. 2022;56(1):127-131Metadata
Show full item recordCollections
Copyright 2022 The Author(s)