Browsing Doktorgradsavhandlinger (NT-fak) by Title

Now showing items 150-169 of 291

    • Method development towards synthesis of carbapenemase inhibitors 

      Ismael, Aya (Doctoral thesis; Doktorgradsavhandling, 2020-10-26)
      Carbapenemases are enzymes able to hydrolyze the last resort b-lactam antibiotics (carbapenems), which are used for the treatment of infections caused by resistant bacteria. Carbapenemases are structurally and mechanistically classified into serine-b-lactamases (SBLs) and metallo-b-lactamases (MBLs). In order to combat the hydrolytic activity of these enzymes, combination therapy of b-lactam with ...

    • Methods for enhanced learning using wearable technologies. A study of the maritime sector 

      Xue, Hui (Doctoral thesis; Doktorgradsavhandling, 2023-10-04)
      Maritime safety is a critical concern due to the potential for serious consequences or accidents for the crew, passengers, environment, and assets resulting from navigation errors or unsafe acts. Traditional training methods face challenges in the rapidly evolving maritime industry, and innovative training methods are being explored. This study explores the use of wearable sensors with biosignal ...

    • Mid/Late Devonian-Carboniferous extensional faulting in Finnmark and the SW Barents Sea 

      Koehl, Jean-Baptiste Philippe (Doctoral thesis; Doktorgradsavhandling, 2018-05-24)
      In northern Norway, late/post-Caledonian extension initiated along inverted, brittle-ductile thrusts, e.g. Sørøya-Ingøya shear zone, which truncated existing, margin-oblique, late Neoproterozoic, Timanian faults and margin-parallel, latest Mesoproterozoic-mid Neoproterozoic faults related to the opening of the Asgard Sea and Iapetus Ocean. Inverted thrusts were active through the Devonian and early ...

    • Millennial-scale variability of Atlantic water inflow in the northern Nordic Seas and the northwestern Barents Sea - Relationship to abrupt climate oscillations, cryosphere and methane seepage from the seafloor 

      El Bani Altuna, Naima (Doctoral thesis; Doktorgradsavhandling, 2021-09-17)
      Climate change affects the Arctic to a greater extent than the global average, causing rapid sea-ice loss and changes in the inflow of warm Atlantic water in the Arctic. Arctic sediments host vast amounts of greenhouse gases in the form of gas hydrates (ice-like cages that trap gas within), that can be released to the seafloor if temperature increases and/or pressure decreases. Climate projections ...

    • Minor element abundances in the corona and solar wind 

      Byhring, Hanne Sigrun (Doctoral thesis; Doktorgradsavhandling, 2011-10-21)
      Using a time-dependent numerical model that spans the chromosphere, corona and solar wind, abundance variations resulting from gravitational settling in the chromosphere and corona have been studied. \noindent Gravitational settling in the chromosphere may lead to a depletion in the abundances of minor elements in the solar wind relative to the photosphere. The observed overabundance (relative ...

    • Model based Statistics for Protein Sequence Families 

      Ahmed, Said Hassan (Doctoral thesis; Doktorgradsavhandling, 2011-07-01)

    • Model-Driven Software Development for Continuity of Care Information Systems - Toolchain design and evaluation 

      Walderhaug, Ståle (Doctoral thesis; Doktorgradsavhandling, 2013-03-13)
      This thesis summarizes six years of design, development and evaluation of a model- driven development toolchain and design of software services for continuity of care. The overall research method has been design science, with a strong focus on creating and evaluating the core artefact: the ModelHealth Toolchain. Three iterations with toolchain design and assessments were deemed necessary to be able ...

    • Modeling Energy Consumption of Computing Systems: from Homogeneous to Heterogeneous Systems 

      Tran, Vi Ngoc-Nha (Doctoral thesis; Doktorgradsavhandling, 2019-09-06)
      Nowadays, reducing energy consumption and improving the energy efficiency of computing systems become ones of the leading research topics in computer science. In order to improve energy efficiency, it is crucial to understand how computing systems consume energy. Power and energy models provide prediction and insight into how computing systems consume power and energy. However, it is challenging to ...

    • Modelling the subglacial hydrology of the former Barents Sea Ice Sheet 

      Gudlaugsson, Eythor (Doctoral thesis; Doktorgradsavhandling, 2015-12-01)
      Ice dynamics are strongly controlled by processes taking place at the interface between the ice and the underlying bed. In modern day ice sheets, up to 90% of mass is lost through fast-flowing corridors of ice, called ice streams. These are typically underlain by a thin layer of water and wet sediment, both of which promote fast flow. In recent years it has emerged that subglacial hydrology played ...

    • The molecular origin of cold adaptation: A comparative study of cold- and warm-active uracil DNA glycosylase 

      Olufsen, Magne (Doctoral thesis; Doktorgradsavhandling, 2007-05-25)
      During the last decade or so, scientists at the Norwegian Structural Biology Centre (NorStruct) have used the enzyme uracil DNA glycosylase (UDG) as a model system in the study of cold-adaptation, protein-DNA recognition and enzyme specificity. The cod UDG (cUDG) and human UDG (hUDG) are thoroughly biologically characterized and there are established well-functioning recombinant expression systems ...

    • Monitoring of Marine Ice and its Thickness for Ship Anti-/De-icing - Experimental and Analytical Study using Infrared Thermography 

      Rashid, Taimur (Doctoral thesis; Doktorgradsavhandling, 2019-03-01)
      Ships operating in a cold climate face many challenges. There are several associated risks such as safety concerns, down time, energy consumption and limited resources. Amongst the key challenges, ship ice accretion is significant for cold climate operations. Exposing superstructures to the marine icing phenomenon can affect the ship’s operations, risking the safety of humans and machines. In this ...

    • Mountain building processes in the northern Norwegian Caledonides - Examining Caledonian continental collision using a combination of structural mapping, phase equilibrium modelling and geochronology 

      Faber, Carly (Doctoral thesis; Doktorgradsavhandling, 2018-01-17)
      Studying orogenesis allows us to better understand the construction of continental crust and the lower crustal processes that occur in modern orogenic belts (e.g. the Himalaya). The Scandinavian Caledonides formed when Laurentia and Baltica collided during the Silurian/Devonian, and allow for direct study of mid- to lower crustal metamorphism in a continental collision zone. This work focuses on the ...

    • Multi-frequency radar remote sensing of sea ice. Modelling and interpretation of polarimetric multi-frequency radar signatures of sea ice 

      Grahn, Jakob (Doctoral thesis; Doktorgradsavhandling, 2018-06-08)
      This thesis deals with polarimetric multi-frequency radar signatures of sea ice. It presents a thorough background on the topic and three case studies. The first study presents a global sensitivity analysis of the fully polarimetric radar backscatter response from snow covered sea ice. The analysis is global in the sense that it takes into account the observed ranges of sea ice properties that ...

    • Multi-Locality Based Local and Symbiotic Computing for Interactively fast On-Demand Weather Forecasting for Small Regions, Short Durations, and Very High-Resolutions 

      Fjukstad, Bård (Doctoral thesis; Doktorgradsavhandling, 2014-09-19)
      Modern weather forecasting is based on forecasts from huge numerical models executed on large supercomputer clusters in large computer centers. Production deadlines for forecast and available computational resources are the main factors for having to limit the forecast region size, spatial resolution, forecast duration and detail level of the weather model used. Modern numerical models currently ...

    • A multi-proxy approach for reconstructing oceanographic dynamics during the Holocene Development and Application of benthic foraminifera as proxies in the Polar North Atlantic 

      Skirbekk, Kari (Doctoral thesis; Doktorgradsavhandling, 2014-10-23)
      Two sediment cores and several sediment surface samples have been retrieved in order to develop and apply benthic foraminifera as proxies in the Polar North Atlantic. The purpose of the surface samples was to develop the Mg/Ca method for cold water environments, as this has been proven a valuable paleo-thermometer for several marine environments. This was done for three species of Benthic foraminifera: ...

    • A multidisciplinary subsurface analysis of mud volcanoes and salt diapirs in European Seas 

      Perez-Garcia, Carolina (Doctoral thesis; Doktorgradsavhandling, 2012-09-13)

    • Multimodal Integrated Remote Sensing for Arctic Sea Ice Monitoring 

      Khachatrian, Eduard (Doctoral thesis; Doktorgradsavhandling, 2023-06-15)
      Remote sensing data acquired from various sensors have been used for decades to monitor sea ice conditions over polar regions. Sea ice plays an essential role in the polar environment and climate. Furthermore, sea ice affects anthropogenic activities, including shipping and navigation, the oil and gas industry, fisheries, tourism, and the lifestyle of the indigenous population of the Arctic. With ...

    • Multiple Signal Classification Algorithm: A computational microscopy tool for fluorescence microscopy 

      Acuna Maldonado, Sebastian Andres (Doctoral thesis; Doktorgradsavhandling, 2023-12-11)
      Fluorescence Microscopy is still the most preferred tool for studying the cell's inner structures. One of the reasons for this preference is its great selectivity, which allows it to label specific types of structures and visualize them with high contrast. However, its resolution is conventionally limited due to the diffraction of light, which makes the study of cells at scales below 200 nm challenging. ...

    • Multiscale Methods for Statistical Inference on Regular Lattice Data 

      Thon, Kevin Otto (Doctoral thesis; Doktorgradsavhandling, 2013-12-13)
      This thesis presents methods for multiscale statistical inference on random fields on a regular two-dimensional lattice. There are two distinct concepts of scale that are used in the thesis. The first one is connected to the computer vision community's understanding of scale-space as a family of smooths of a digital image, with fine structure being revealed at low levels of smoothing and the coarser ...

    • Multitemporal Analysis of Multipolarization Synthetic Aperture Radar Images for Robust Surface Change Detection 

      Akbari, Vahid (Doctoral thesis; Doktorgradsavhandling, 2013-06-07)
      This thesis addresses two approaches for change detection from multipolarization, multilooked SAR images: a post-classification comparison and a direct change detection. We consider the complete workflow associated with performing post-classification change detection from time series of multipolarization SAR (PolSAR) images acquired with different imaging geometries and polarimetric configurations. ...