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dc.contributor.authorBerdal, Elias Kjølseth
dc.contributor.authorWollum, Arnt Erik Karlsen
dc.contributor.authorHollund, Ingrid Marie Husby
dc.contributor.authorIversen, Johanne Marie
dc.contributor.authorKajantie, Eero Olavi
dc.contributor.authorEvensen, Kari Anne Indredavik
dc.date.accessioned2023-01-09T13:33:08Z
dc.date.available2023-01-09T13:33:08Z
dc.date.issued2022-09-14
dc.description.abstractBackground: Preterm birth with very low birth weight (VLBW, birth weight<1500 g) is associated with health problems later in life. How VLBW individuals perceive their physical and mental health-related quality of life (HRQoL) is important to understand their putative burden of disease. Previous studies have shown mixed results, and longitudinal studies into adulthood have been requested. This study aimed to investigate diferences in HRQoL between preterm VLBW and term born individuals at 32 years of age, and to study changes in HRQoL from 20 to 32 years.<p> <p>Methods: In a geographically based longitudinal study, 45 VLBW and 68 term born control participants completed the Short Form 36 Health Survey (SF-36) at 32 years of age. Data from three previous timepoints was also available (20, 23 and 28 years of age). The SF-36 yields eight domain scores as well as a physical and a mental component summary. Between-group diferences in these variables were investigated. We also performed subgroup analyses excluding individuals with disabilities, i.e., cerebral palsy and/or low estimated intelligence quotient. <p>Results: At 32 years of age, the physical component summary was 5.1 points lower (95% confdence interval (CI): 8.6 to 1.6), and the mental component summary 4.1 points lower (95% CI: 8.4 to −0.3) in the VLBW group compared with the control group. For both physical and mental component summaries there was an overall decline in HRQoL from 20 to 32 years of age in the VLBW group. When we excluded individuals with disabilities (n=10), group diferences in domain scores at 32 years were reduced, but physical functioning, bodily pain, general health, and role-emotional scores remained lower in the VLBW subgroup without disabilities compared with the control group. <p>Conclusion: We found that VLBW individuals reported lower HRQoL than term born controls at 32 years of age, and that HRQoL declined in the VLBW group from 20 to 32 years of age. This was in part, but not exclusively explained by VLBW individuals with disabilities.en_US
dc.identifier.citationBerdal, Wollum, Hollund, Iversen, Kajantie, Evensen. Health-related quality of life from 20 to 32 years of age in very low birth weight individuals: a longitudinal study. Health and Quality of Life Outcomes. 2022;20(1)en_US
dc.identifier.cristinIDFRIDAID 2071801
dc.identifier.doi10.1186/s12955-022-02044-3
dc.identifier.issn1477-7525
dc.identifier.urihttps://hdl.handle.net/10037/28094
dc.language.isoengen_US
dc.publisherBMCen_US
dc.relation.journalHealth and Quality of Life Outcomes
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H-2020/733280/EU/Research on European Children and Adults born Preterm/RECAP preterm/en_US
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2022 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.titleHealth-related quality of life from 20 to 32 years of age in very low birth weight individuals: a longitudinal studyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)