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dc.contributor.authorGranerud, Beathe Kiland
dc.contributor.authorUeland, Thor
dc.contributor.authorLind, Andreas
dc.contributor.authorSøraas, Arne Vasli
dc.contributor.authorFevang, Børre
dc.contributor.authorSteffensen, Anne Katrine
dc.contributor.authorAl-Baldawi, Huda
dc.contributor.authorLund-Johansen, Fridtjof
dc.contributor.authorAukrust, Pål
dc.contributor.authorHalvorsen, Bente Evy
dc.contributor.authorDahl, Tuva Børresdatter
dc.contributor.authorDudman, Susanne
dc.contributor.authorMüller, Fredrik
dc.contributor.authorHolter, Jan Cato
dc.date.accessioned2023-01-11T12:27:08Z
dc.date.available2023-01-11T12:27:08Z
dc.date.issued2022-10-31
dc.description.abstractThe Omicron variant of SARS-CoV-2 spreads more easily than earlier variants, possibly as a result of a higher viral load in the upper respiratory tract and oral cavity. Hence, we investigated whether the Omicron variant generates a higher viral load than that of the Delta variant in saliva and nasopharynx. Both specimens were collected from 52 Omicron and 17 Delta cases at two time points one week apart and analyzed by qRT-PCR. Viral load was measured as 10 log RNA genome copies per 1000 human cells according to the WHO reference standard. We found that Omicron cases carried a higher viral load and had more sustained viral shedding compared to the Delta cases, especially in the nasopharynx.en_US
dc.identifier.citationGranerud, Ueland, Lind, Søraas, Fevang, Steffensen, Al-Baldawi, Lund-Johansen, Aukrust, Halvorsen, Dahl, Dudman, Müller, Holter. Omicron Variant Generates a Higher and More Sustained Viral Load in Nasopharynx and Saliva Than the Delta Variant of SARS-CoV-2. Viruses. 2022;14(11)en_US
dc.identifier.cristinIDFRIDAID 2074735
dc.identifier.doi10.3390/v14112420
dc.identifier.issn1999-4915
dc.identifier.urihttps://hdl.handle.net/10037/28156
dc.language.isoengen_US
dc.publisherMDPIen_US
dc.relation.journalViruses
dc.relation.projectIDOslo universitetssykehus HF: Fredrik Mülleren_US
dc.relation.projectIDVivaldi Invest: Jan Cato Holteren_US
dc.relation.projectIDNorges forskningsråd: 312780en_US
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2022 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.subjectVDP::Medisinske fag: 700::Basale medisinske, odontologiske og veterinærmedisinske fag: 710::Medisinsk mikrobiologi : 715en_US
dc.subjectVDP::Midical sciences: 700::Basic medical, dental and veterinary sciences: 710::Medical microbiology: 715en_US
dc.subjectSARS-CoV-2 / SARS-CoV-2en_US
dc.titleOmicron Variant Generates a Higher and More Sustained Viral Load in Nasopharynx and Saliva Than the Delta Variant of SARS-CoV-2en_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)