Rapid cross-border emergence of NDM-5-producing Escherichia coli in the European Union/European Economic Area, 2012 to June 2022

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https://hdl.handle.net/10037/29918
DOI
https://doi.org/10.2807/1560-7917.ES.2023.28.19.2300209
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Date
2023-05-11
Type
Journal article
Tidsskriftartikkel
Peer reviewed

Author
Linkevicius, Marius; Bonnin, Rémy A; Alm, Erik; Svartström, Olov; Apfalter, Petra; Hartl, Rainer; Hasman, Henrik; Roer, Louise; Räisänen, Kati; Dortet, Laurent; Pfennigwerth, Niels; Hans, Jörg B; Tóth, Ákos; Buzgó, Lilla; Cormican, Martin; Delappe, Niall; Monaco, Monica; Giufrè, Maria; Hendrickx, Antoni Pa; Samuelsen, Ørjan; Pöntinen, Anna Kaarina; Caniça, Manuela; Manageiro, Vera; Oteo-Iglesias, Jesús; Pérez-Vázquez, María; Westmo, Karin; Mäkitalo, Barbro; Palm, Daniel; Monnet, Dominique L.; Kohlenberg, Anke
Abstract
Whole genome sequencing data of 874 Escherichia coli isolates carrying blaNDM-5 from 13 European Union/ European Economic Area countries between 2012 and June 2022 showed the predominance of sequence types ST167, ST405, ST410, ST361 and ST648, and an increasing frequency of detection. Nearly a third (30.6%) of these isolates were associated with infections and more than half (58.2%) were predicted to be multidrug-resistant. Further spread of E. coli carrying blaNDM-5 would leave limited treatment options for serious E. coli infections.
Publisher
European Centre for Disease Prevention and Control
Citation
Linkevicius, Bonnin, Alm, Svartström, Apfalter, Hartl, Hasman, Roer, Räisänen, Dortet, Pfennigwerth, Hans, Tóth, Buzgó, Cormican, Delappe, Monaco, Giufrè, Hendrickx, Samuelsen, Pöntinen, Caniça, Manageiro, Oteo-Iglesias, Pérez-Vázquez, Westmo, Mäkitalo, Palm, Monnet, Kohlenberg. Rapid cross-border emergence of NDM-5-producing Escherichia coli in the European Union/European Economic Area, 2012 to June 2022. Eurosurveillance. 2023;28(19)
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Except where otherwise noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)