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dc.contributor.authorQin, Yingying
dc.contributor.authorButola, Ankit
dc.contributor.authorAgarwal, Krishna
dc.date.accessioned2023-12-29T10:33:47Z
dc.date.available2023-12-29T10:33:47Z
dc.date.issued2023-11-27
dc.description.abstractReconstructing 3D refractive index profile of scatterers using optical microscopy measurements presents several challenges over the conventional microwave and RF domain measurement scenario. These include phaseless and polarization-insensitive measurements, small numerical aperture, as well as a Green's function where spatial frequencies are integrated in a weighted manner such that far-field angular spectrum cannot be probed and high spatial frequencies that permit better resolution are weighed down. As a result of these factors, the non-linearity and the ill-posedness of the inverse problem are quite severe. These limitations have imposed that inverse scattering problems in the microscopy domain largely consider scalar wave approximations and neglect multiple scattering. Here, we present first inverse scattering results for optical microscopy setup where full-wave vectorial formulation and multiple scattering is incorporated. We present (a) how three popular inverse scattering solvers from microwave domain can be adapted for the present inverse problem, (b) the opportunities and challenges presented by each of these solvers, (c) a comparative insight into these solvers and contrast with the simpler Born approximation approach, and (d) potential routes to improve the performance of these solvers for the hard inverse problem of optical microscopy.en_US
dc.identifier.citationQin, Butola, Agarwal. 3D refractive index reconstruction from phaseless coherent optical microscopy data using multiple scattering-based inverse solvers - a study. Inverse Problems. 2023en_US
dc.identifier.cristinIDFRIDAID 2198922
dc.identifier.doi10.1088/1361-6420/ad0c29
dc.identifier.issn0266-5611
dc.identifier.issn1361-6420
dc.identifier.urihttps://hdl.handle.net/10037/32265
dc.language.isoengen_US
dc.publisherIOP Publishingen_US
dc.relation.journalInverse Problems
dc.relation.projectIDNorges forskningsråd: 288082en_US
dc.relation.projectIDEU – Horisont Europa (EC/HEU): 804233en_US
dc.relation.projectIDEU – Horisont Europa (EC/HEU): 964800en_US
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/804233/Norway/Label-free 3D morphological nanoscopy for studying sub-cellular dynamics in live cancer cells with high spatio-temporal resolution/3D-nanoMorph/en_US
dc.relation.projectIDinfo:eu-repo/grantAgreement/EC/H2020/964800/Norway/OrganVision: Technology for real-time visualizing and modelling of fundamental process in living organoids towards new insights into organ-specific health, disease, and recovery/OrganVision/en_US
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2023 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)en_US
dc.title3D refractive index reconstruction from phaseless coherent optical microscopy data using multiple scattering-based inverse solvers - a studyen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution 4.0 International (CC BY 4.0)
Med mindre det står noe annet, er denne innførselens lisens beskrevet som Attribution 4.0 International (CC BY 4.0)