dc.contributor.author | Harboe-Sjåvik, Hege | |
dc.contributor.author | Endresen, Kristoffer Hammer | |
dc.contributor.author | Åsheim, Sandra Elena | |
dc.contributor.author | Sundsfjord, Arnfinn Ståle | |
dc.date.accessioned | 2024-08-29T11:28:21Z | |
dc.date.available | 2024-08-29T11:28:21Z | |
dc.date.issued | 2024-01-12 | |
dc.description.abstract | We have evaluated the performance of FilmArray BCID2 in reactive blood cultures in a small acute care hospital compared to conventional diagnostics at a regional microbiological laboratory. This is a retrospective observational study of BactAlert reactive blood cultures (n = 160) from Helgeland Hospital, July–December 2021, analysed by BCID2 locally and conventional culture at a regional laboratory. The overall clinical and analytic sensitivity with BCID2 were 87.2% and 97.8%, respectively. The false-negative BCID2 rate was low (n = 4; 2.9%). No false-positive BCID2 results were observed. The BCID2 data were available on average 1.88 days earlier than culture-based results, due to long transport time to the regional laboratory. The BCID2 provided results to support a significantly earlier optimized targeted antibiotic treatment in 27% of the cases according to national guidelines for empirical treatment of BSI. The high clinical and analytical sensitivity, and specificity support the use of BCID2 as a robust supplement to traditional cultivation of positive blood cultures. The significant time gain to microbial identification and detection of resistance determinants suggests a great clinical importance of BCID2 in small acute care hospitals with long transport time to conventional clinical microbiology services. | en_US |
dc.identifier.citation | Harboe-Sjåvik, Endresen, Åsheim, Sundsfjord. FilmArray (BCID2) provides essential and timely results in bloodstream infections in small acute care hospitals without conventional microbiology services. APMIS - Journal of Pathologiy, Microbiology and Immunology. 2024 | en_US |
dc.identifier.cristinID | FRIDAID 2245484 | |
dc.identifier.doi | 10.1111/apm.13374 | |
dc.identifier.issn | 0903-4641 | |
dc.identifier.issn | 1600-0463 | |
dc.identifier.uri | https://hdl.handle.net/10037/34464 | |
dc.language.iso | eng | en_US |
dc.publisher | Wiley | en_US |
dc.relation.journal | APMIS - Journal of Pathologiy, Microbiology and Immunology | |
dc.rights.accessRights | openAccess | en_US |
dc.rights.holder | Copyright 2024 The Author(s) | en_US |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/4.0 | en_US |
dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) | en_US |
dc.title | FilmArray (BCID2) provides essential and timely results in bloodstream infections in small acute care hospitals without conventional microbiology services | en_US |
dc.type.version | publishedVersion | en_US |
dc.type | Journal article | en_US |
dc.type | Tidsskriftartikkel | en_US |
dc.type | Peer reviewed | en_US |