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dc.contributor.authorHarboe-Sjåvik, Hege
dc.contributor.authorEndresen, Kristoffer Hammer
dc.contributor.authorÅsheim, Sandra Elena
dc.contributor.authorSundsfjord, Arnfinn Ståle
dc.date.accessioned2024-08-29T11:28:21Z
dc.date.available2024-08-29T11:28:21Z
dc.date.issued2024-01-12
dc.description.abstractWe have evaluated the performance of FilmArray BCID2 in reactive blood cultures in a small acute care hospital compared to conventional diagnostics at a regional microbiological laboratory. This is a retrospective observational study of BactAlert reactive blood cultures (n = 160) from Helgeland Hospital, July–December 2021, analysed by BCID2 locally and conventional culture at a regional laboratory. The overall clinical and analytic sensitivity with BCID2 were 87.2% and 97.8%, respectively. The false-negative BCID2 rate was low (n = 4; 2.9%). No false-positive BCID2 results were observed. The BCID2 data were available on average 1.88 days earlier than culture-based results, due to long transport time to the regional laboratory. The BCID2 provided results to support a significantly earlier optimized targeted antibiotic treatment in 27% of the cases according to national guidelines for empirical treatment of BSI. The high clinical and analytical sensitivity, and specificity support the use of BCID2 as a robust supplement to traditional cultivation of positive blood cultures. The significant time gain to microbial identification and detection of resistance determinants suggests a great clinical importance of BCID2 in small acute care hospitals with long transport time to conventional clinical microbiology services.en_US
dc.identifier.citationHarboe-Sjåvik, Endresen, Åsheim, Sundsfjord. FilmArray (BCID2) provides essential and timely results in bloodstream infections in small acute care hospitals without conventional microbiology services. APMIS - Journal of Pathologiy, Microbiology and Immunology. 2024en_US
dc.identifier.cristinIDFRIDAID 2245484
dc.identifier.doi10.1111/apm.13374
dc.identifier.issn0903-4641
dc.identifier.issn1600-0463
dc.identifier.urihttps://hdl.handle.net/10037/34464
dc.language.isoengen_US
dc.publisherWileyen_US
dc.relation.journalAPMIS - Journal of Pathologiy, Microbiology and Immunology
dc.rights.accessRightsopenAccessen_US
dc.rights.holderCopyright 2024 The Author(s)en_US
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0en_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)en_US
dc.titleFilmArray (BCID2) provides essential and timely results in bloodstream infections in small acute care hospitals without conventional microbiology servicesen_US
dc.type.versionpublishedVersionen_US
dc.typeJournal articleen_US
dc.typeTidsskriftartikkelen_US
dc.typePeer revieweden_US


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Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)
Med mindre det står noe annet, er denne innførselens lisens beskrevet som Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)