Now showing items 1157-1176 of 10152

    • Can we reliably measure cognitive effort? On the relation of implicit and explicit cognitive effort scales and tasks. 

      Mækelæ, Martin Jensen (Mastergradsoppgave; Master thesis, 2021-04-01)
      We tend to choose the action that is least demanding however measuring individual differences in the cost of cognitive effort can be elusive. We here report a set of five studies studying the relationship between four cognitive effort measures: the demand selection task, the cognitive effort discounting paradigm, a rationality battery to assess deliberate reasoning, and the Need for Cognition scale. ...
    • Can we rely on simulated patients' satisfaction with their consultation for assessing medical students' communication skills? A cross-sectional study 

      Gude, Tore; Grimstad, Hilde; Holen, Are; Anvik, Tor; Baerheim, Anders; Fasmer, Ole Bernt; Hjortdahl, Per; Vaglum, Per Jørgen Wiggen (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-12-18)
      Background: In medical education, teaching methods offering intensive practice without high utilization of faculty resources are needed. We investigated whether simulated patients’ (SPs’) satisfaction with a consultation could predict professional observers’ assessment of young doctors’ communication skills. <p>Methods: This was a comparative cross-sectional study of 62 videotaped consultations ...
    • Cancer and venous thromboembolism 

      Jensvoll, Hilde (Doctoral thesis; Doktorgradsavhandling, 2015-10-02)
      Venøs tromboembolisme (VTE) er et samlebegrep for lungeemboli og dyp venetrombose. VTE rammer ofte kreftpasienter og representerer en ledende dødsårsak i denne pasient gruppen. Dette understreker viktigheten av å kartlegge risikofaktorer for kreft-relatert VTE for å muliggjøre forebyggende behandling hos pasienter med høy risiko. En VTE hendelse kan også være det første symptomet på en bakenforliggende ...
    • Cancer associated fibroblasts and their regulatory functions in the context of radiotherapy 

      Lode, Kristin (Doctoral thesis; Doktorgradsavhandling, 2023-08-25)
      <p>Tumours are highly complex tissues comprised of both malignant tumour cells and non-malignant healthy cells. Cells and tissues surrounding solid tumours make out the stroma, which provide physical support to the growing tumour structures, in addition to provide nutrients and facilitate waste removal. In the last four decades, it has become increasingly evident that stromal cells play important ...
    • Cancer associated fibroblasts in stage I-IIIA NSCLC: Prognostic impact and their correlations with tumor molecular markers 

      Kilvær, Thomas Karsten; Rakaeekhanehkenari, Mehrdad; Hellevik, Turid; Al-Saad, Samer; Paulsen, Erna-Elise; Busund, Lill-Tove; Dønnem, Tom; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-08-07)
      Background Cancer Associated Fibroblasts (CAFs) are thought to regulate tumor growth and metastasis. Fibroblast Activating Protein 1 (FAP-1) is a marker for fibroblast activation and by many recognized as the main marker of CAFs. Alpha Smooth Muscle Actin (α-SMA) is a general myofibroblast marker, and can be used to identify CAFs. This study investigates the prognostic impact of FAP-1 and α-SMA ...
    • Cancer cervicis uteri i Sub-Sahara Afrika : en litteraturstudie 

      Hana, Johan (Master thesis; Mastergradsoppgave, 2011-09-15)
      Insidensen av livmorhalskreft i regionen er blant verdens høyeste. Kontinentet er hardt rammet av HIV/AIDS, og da denne sykdommen medfører smitte av andre og flere typer onkogene HPV, samt raskere progresjon av dysplasi, vanskeliggjør dette arbeidet med å få ned nye krefttilfeller. Videre viser studier generelt manglende kunnskap om livmorhalskreft i befolkningen, også blant velutdannende og urbane ...
    • Cancer detection for white urban Americans 

      Møllersen, Kajsa; Bongo, Lars Ailo; Tafavvoghi, Masoud (Conference object; Konferansebidrag, 2023-06)
      Development, validation and comparison of machine learning methods require access to data, sometimes lots of data. Within health applications, data sharing can be restricted due to patient privacy, and the few publicly available data sets become even more valuable for the machine learning community. One such type of data are H&E whole slide images (WSI), which are stained tumour tissue, used in ...
    • Cancer drugs as drivers of antibiotic resistance 

      Guðmundsdóttir, Jónína (Doctoral thesis; Doktorgradsavhandling, 2023-09-15)
      Antibiotics are the cornerstone for modern medicine, and their introduction into clinical use has made common medical procedures such as surgeries and cancer chemotherapy possible. The consequences of antimicrobial resistance (AMR), if it continues to rise on a global scale at its current speed, are expected to be staggering. It is well-known that antibiotics drive the evolution and spread of AMR, ...
    • Cancer incidence and mortality among firefighters 

      Jalilian, Hamed; Ziaei, Mansour; Weiderpass, Elisabete; Rueegg, Corina Silvia; Khosravi, Yahya; Kjærheim, Kristina (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-08)
      Firefighters are exposed to both known and suspected carcinogens. This study aims to systematically review the literature on the association of firefighting occupation and cancer incidence and mortality, overall and for specific cancer sites. A systematic review using PubMed, Embase, and Web of Science was performed up to January 1, 2018. We extracted risk estimates of cancers and calculated summary ...
    • Cancer incidence and mortality in Chukotka, 1997–2010 

      Dudarev, AA; Chupakhin, Valery; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Objectives. The general aim was to assess cancer incidence and mortality among the general population of Chukotka in 1997 2010 and to compare it with the population of Russia. Methods. Cancer data were abstracted from the annual statistical reports of the P.A. Hertzen Research Institute of Oncology in Moscow. The annual number and percent of cases, crude and age-standardized cancer incidence ...
    • Cancer incidence in Arkhangelskaja Oblast in northwestern Russia. The Arkhangelsk Cancer Registry 

      Vaktskjold, Arild; Lebedintseva, Jelena A.; Korotov, Dmitrij S.; Lund, Eiliv; Tkatsjov, Anatolij V.; Podjakova, Tatjana S. (Journal article; Tidsskriftartikkel; Peer reviewed, 2005-07-19)
      Background: Data concerning incidence and prevalence of cancer in the different regions of Russia have traditionally not been provided on a basis that facilitated comparison with data from countries in western parts of Europe. The oncological hospital in Arkhangelsk, in co-operation with Universitetet i Tromsø (Norway), has established a population based cancer registry for Arkhangelskaja Oblast ...
    • The cancer may come back: experiencing and managing worries of relapse in a North Norwegian village after treatment 

      Skowronski, Magdalena; Risør, Mette Bech; Andersen, Rikke Sand; Foss, Nina (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-18)
      Little is known about how people living in the aftermath of cancer treatment experience and manage worries about possible signs of cancer relapse, not as an individual enterprise but as socially embedded management. One-year ethnographic fieldwork was conducted in a coastal village of under 3000 inhabitants in northern Norway. Ten villagers who had undergone cancer treatment from six months to five ...
    • Cancer mortality in the indigenous population of coastal Chukotka, 1961–1990 

      Dudarev, Alexy A.; Chupakhin, Valery; Odland, Jon Øyvind (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
      Objectives. The general aim was to assess the pattern and trend in cancer mortality among the indigenous people of coastal Chukotka during the period 1961 1990. Methods. All cases of cancer deaths of indigenous residents of the Chukotsky district in the northeasternmost coast of Chukotka Autonomous Okrug were copied from personal death certificates. There were a total of 219 cancer deaths during ...
    • Cancer Research 

      Konstantinell, Aelita Gloria Virginia (Journal article; Tidsskriftartikkel, 2017)
      American Association for Cancer Research was founded in 1907 by a group of 11 physicians and scientists interested in cancer research in the Washington, DC. Today, the AACR is the largest professional organization in the world with a membership of 37 000 researchers from 108 countries. This year, AAR Annual Meeting was organized from the 1th to 5th of April in the birthplace of the organization. I ...
    • Cancer survivors' experiences of humour while navigating through challenging landscapes - a socio-narrative approach 

      Roaldsen, Bente Lisbet; Sørlie, Tore; Lorem, Geir F (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-03-10)
      Aim: Humour is seen as a health-promoting coping strategy when dealing with life stress. The aim is to elucidate how adult cancer survivors experience and evaluate the significance of humour in daily life, from diagnosis through their entire illness trajectory, and to gain a broader understanding of humour as part of stress-coping processes during the experience of cancer as a life-threatening ...
    • Cancer therapy-induced oral mucositis in head and neck cancer patients 

      Gussgard, Anne Margrete (Doctoral thesis; Doktorgradsavhandling, 2015-06-17)
      Background: Radiotherapy causes oral mucositis (OM) that is painful and disrupts eating, talking, social activities and general health. OM may even interrupt cancer therapy. Any intervention that can reduce OM will lead to improvement in treatment and quality of life for patients. It is essential to have a suitable tool to measure potentially effective and new treatments against OM. Objective: To ...
    • Cancer-associated fibroblasts from human NSCLC survive ablative doses of radiation but their invasive capacity is reduced 

      Hellevik, Turid; Pettersen, ingvild; Berg, Vivian; Winberg, Jan-Olof; Moe, Bjørn Torvald Greve; Bartnes, Kristian; Paulssen, Ruth H; Busund, Lill-Tove; Bremnes, Roy M.; Chalmers, Antony; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      BACKGROUND: Cancer-Associated Fibroblasts (CAFs) are significant components of solid malignancies and play central roles in cancer sustainability, invasion and metastasis. In this study we have investigated the invasive capacity and matrix remodelling properties of human lung CAFs after exposure to ablative doses of ionizing radiation (AIR), equivalent to single fractions delivered by stereotactic ...
    • Cancer-associated fibroblasts from lung tumors maintain their immunosuppressive abilities after high-dose irradiation 

      Gorchs, Laia; Hellevik, Turid; Bruun, Jack-Ansgar; Camilio, Ketil Andre; Al-Saad, Samer; Stuge, Tor Brynjar; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-05-12)
      Accumulating evidence supports the notion that high-dose (>5 Gy) radiotherapy (RT) regimens are triggering stronger pro-immunogenic effects than standard low-dose (2 Gy) regimens. However, the effects of RT on certain immunoregulatory elements in tumors remain unexplored. In this study, we have investigated the effects of high-dose radiotherapy (HD-RT) on the immunomodulating functions of cancer-associated ...
    • Cancer-associated fibroblasts in radiotherapy: Bystanders or protagonists? 

      Martinez, Inigo Zubiavrre; Hellevik, Turid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-11)
      Background - The primary goal of radiotherapy (RT) is to induce cellular damage on malignant cells; however, it is becoming increasingly recognized the important role played by the tumor microenvironment (TME) in therapy outcomes. Therapeutic irradiation of tumor lesions provokes profound cellular and biological reconfigurations within the TME that ultimately may influence the fate of the ...
    • Cancer-before-cancer. Mythologies of cancer in everyday life 

      Offersen, Sara Marie Hebsgaard; Risør, Mette Bech; Vedsted, Peter; Andersen, Rikke Sand (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-19)
      Approaching the presence of cancer in everyday life in terms of mythologies, the article examines what cancer is and how cancer-related potentialities are enacted and embodied in the context of contemporary regimes of anticipation. Based on ethnographic fieldwork in a suburban Danish middle-class community among people who were not immediately afflicted by cancer, we describe different and ...