Browsing Det helsevitenskapelige fakultet by Title

Now showing items 1507-1526 of 10152

    • Close to zero preventable in-hospital deaths in pediatric trauma patients – An observational study from a major Scandinavian trauma center 

      Ringen, Amund Hovengen; Baksaas-Aasen, Kjersti; Skaga, Nils Oddvar; Wisborg, Torben; Gaarder, Aslaug Christine; Næss, Pål Aksel (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-30)
      Background: In line with international trends, initial treatment of trauma patients has changed substantially over the last two decades. Although trauma is the leading cause of death and disability in children globally, in-hospital pediatric trauma related mortality is expected to be low in a mature trauma system. To evaluate the performance of a major Scandinavian trauma center we assessed treatment ...

    • Cluster of linezolid-resistant Enterococcus faecium ST117 in Norwegian hospitals 

      Hegstad, Kristin; Longva, Jørn-Åge; Hide, Reidar; Aasnæs, Bettina; Lunde, Tracy Tamara Munthali; Simonsen, Gunnar Skov (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-08-19)
      A linezolid-resistant, vancomycin-susceptible Enterococcus faecium strain was isolated from 3 patients who had not received linezolid. The first patient was hospitalized in the same hospitals and wards as the 2 following patients. The E. faecium isolates were resistant to linezolid (minimum inhibitory concentration 8–32 mg/l), ampicillin, and high levels of gentamicin. Resistance to linezolid was ...

    • Clustering and trajectories of key noncommunicable disease risk factors in Norway: the NCDNOR project 

      Dalene, Knut Eirik; Lergenmuller, Simon; Sund, Erik Reidar; Hopstock, Laila Arnesdatter; Robsahm, Trude Eid; Nilssen, Yngvar; Nystad, Wenche; Larsen, Inger Kristin; Ariansen, Inger (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-09-02)
      Noncommunicable diseases (NCDs) are a leading cause of premature death globally and have common preventable risk factors. In Norway, the NCDNOR-project aims at establishing new knowledge in the prevention of NCDs by combining information from national registries with data from populationbased health studies. In the present study, we aimed to harmonize data on key NCD risk factors from the health ...

    • Clustering of cardiovascular risk factors and carotid intima-media thickness: The USE-IMT study 

      Wang, Xin; Dalmeijer, Geertje W.; den Ruijter, Hester M.; Anderson, Todd J.; Britton, Annie R.; Dekker, Jacqueline; Engström, Gunnar; Evans, Greg W.; De Graaf, Jacqueline; Grobbee, Diederick E.; Hedblad, Bo; Holewijn, Suzanne; Ikeda, Ai; Kauhanen, Jussi; Kitagawa, Kazuo; Kitamura, Akihiko; Kurl, Sudhir; Lonn, Eva M.; Lorenz, Matthias W.; Mathiesen, Ellisiv B.; Nijpels, Giel; Okazaki, Shuhei; Polak, Joseph F.; Price, Jacqueline F.; Rembold, Christopher M.; Rosvall, Maria; Rundek, Tatjana; Salonen, Jukka T.; Sitzer, Matthias; Stehouwer, Coen D.A.; Tuomainen, Tomi-Pekka; Peters, Sanne A.E.; Bots, Michiel L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-03-21)
      Background:<br>The relation of a single risk factor with atherosclerosis is established. Clinically we know of risk factor clustering within individuals. Yet, studies into the magnitude of the relation of risk factor clusters with atherosclerosis are limited. Here, we assessed that relation.<br>Methods:<br>Individual participant data from 14 cohorts, involving 59,025 individuals were used in this ...

    • Co-constructing standards in nursing 

      Meum, Torbjørg (Doctoral thesis; Doktorgradsavhandling, 2013-04-05)
      Avhandlingen presenterer en kvalitativ studie av innføring og bruk av standarder i sykepleie og bygger på empiriske studier fra ulike sykehusmiljø. Standardisering er ofte ansett som en viktig forutsetning for å oppnå sømløs integrasjon ved bruk av informasjons – og kommunikasjonsteknologi (IKT) i helsesektoren. Terminologier og retningslinjer blir ofte utviklet av internasjonale organisasjoner som ...

    • Co-creating since 1990s: an qualitative analyses of the exploratory case study on a small private health IT company in North Norway though the prism of ANT. 

      Ikoev, Vitalii (Master thesis; Mastergradsoppgave, 2020-05-14)
      Digitalization of healthcare is done through development and delivery of health information technology, mobile health, wearable devices, telehealth, telemedicine, health portals, personalized medicine, or in other words – ehealth. Ehealth solutions are expected to improve the treatment process, improved safety, efficiency and quality, as well as empowerment of both patients and healthcare professionals. ...

    • Co-existence challenges in small-scale farming when farmers share and save seeds 

      Bøhn, Thomas; Aheto, Denis; Mwangala, Felix; Bones, Inger Louise; Simoloka, Christopher; Mbeule, Ireen; Wikmark, Odd Gunnar; Schmidt, Gunther; Chapela, Ignacio (Chapter; Bokkapittel, 2013)
      Gene flow by means of pollen and seeds in maize influences local, regional and global maize biodiversity. Developing countries are centers of diversity for maize and preserve seeds also in informal seed systems. Particularly in poor communities, seed saving and sharing often co-occur with farming on small fields. We present preliminary investigations from a small-scale maize farming community, in ...

    • Co-expression of 1α-hydroxylase and vitamin D receptor in human articular chondrocytes 

      Hansen, Ann Kristin; Figenschau, Yngve Anton; Martinez, Inigo Zubiavrre (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-06)
      Background: <br> The aim was to investigate whether resident chondrocytes in human articular cartilage and in subculture express vitamin D receptor (VDR) and the enzyme that hydroxylates the prohormone 25(OH)D3 to the active hormone 1α,25(OH)2D3, namely 1α-hydroxylase (CYP27B1). Any putative effects of vitamin D on chondrocytes were also explored. <br> Methods: <br> Cartilage from human osteoarthritic ...

    • Co-management of protected areas to alleviate conservation conflicts: Experiences in Norway. 

      Fedreheim, Gunn Elin; Blanco, Ester (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-16)
      This paper addresses the perceptions of actors of protected areas in Norway about a co-management regime at the local level. The analysis is based on quantitative data from surveys of actors of eight protected areas in northern Norway. The surveys were undertaken just before a change to co-management in 2010. The results show that the two strongest determinants that explain actors’ initial ...

    • Co-morbidity and drug treatment in Alzheimer’s disease. A cross sectional study of participants in the Dementia Study in Northern Norway 

      Andersen, Fred; Viitanen, Matti; Halvorsen, Dag; Straume, Bjørn; Engstad, Torgeir (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Inappropriate medical treatment of co-morbidities in Alzheimer’s disease (AD) is an increasing concern in geriatric medicine. The objective of this study was to compare current drug use related to co-morbidity between individuals with a recent diagnosis of AD and a cognitively healthy control group in a population based clinical trial in Northern Norway. Setting: Nine rural municipalities with ...

    • Co-occurrence of avoidant personality disorder and child sexual abuse predicts poor outcome in longstanding eating disorders 

      Rosenvinge, Jan H.; Vrabel, KariAnne R.; Hoffart, Asle; Rø, Øyvind; Martinsen, Egil W. (Journal article; Tidsskriftartikkel; Peer reviewed, 2009-12-16)
      Few consistent predictive factors for eating disorder have been identified across studies. In the current five year prospective study, the objective was to examine whether (1) personality disorder and child sexual abuse predict the course of severity of eating disorder symptoms after inpatient treatment and (2) how the predictors interact. A total of 74 patients with long standing eating disorder ...

    • Co-Occurring Change in Children’s Conduct Problems and Maternal Depression: Latent Class Individual Participant Data Meta-Analysis of the Incredible Years Parenting Program 

      Leijten, Patty; Gardner, Frances; Melendez-Torres, G. J; Weeland, J; Hutchings, J; Landau, Sabine; Mcgilloway, Sinead; Overbeek, Geertjan; van Aar, J; Menting, A; Orobio de Castro, B; Berry, V; Gaspar, Maria Filomena; Axberg, Ulf; Mørch, Willy-Tore; Scott, S (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-02)
      Children vary in the extent to which they benefit from parenting programs for conduct problems. How does parental mental health change if children benefit less or more? We assessed whether changes in conduct problems and maternal depressive symptoms co-occur following participation in the Incredible Years parenting program. We integrated individual participant data from 10 randomized trials (<i>N</i> ...

    • A co-operative evaluation of different methods of detecting BCR-ABL kinase domain mutations in patients with chronic myeloid leukemia on second-line dasatinib or nilotinib therapy after failure of imatinib 

      Ernst, Thomas; Gruber, Franz; Mikkola, Ingvild; Pelz-Ackermann, Oliver; Maier, J; Pfirrmann, M; Muller, MC; Porkka, Kimmo; Niederwieser, D; Hochhaus, A; Lange, T (Journal article; Tidsskriftartikkel; Peer reviewed, 2009)

    • Co-products from the Atlantic salmon filleting industry – Their properties, stability and potential as human food ingredients 

      Ulleberg, Didrik; Sletten, Ingrid Bøe; Jakobsen, Anita Nordeng; Svenning, Jon Brage; Lerfall, Jørgen (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-20)
      The present study impacts the growing knowledge about co-products obtained from the primary processing of Atlantic salmon (Salmo Salar L.) as food ingredients by highlighting their microbial and chemical composition and stability. The proximate composition varied between the co-products from the fatty belly-flap (34% lipid, 15% protein) to the leaner deboned meat (10% fat, 22% protein) (p < 0.001), ...

    • The coagulase negative staphylococci; molecular studies on Staphylococcus haemolyticus and novel treatment of staphylococcal biofilms in vitro and in vivo 

      Cavanagh, Jorunn Pauline (Doctoral thesis; Doktorgradsavhandling, 2013-01-25)
      The coagulase negative staphylococci (CoNS) were earlier regarded as innocuous inhabitants of the human normal skin flora, but are now emerging as opportunistic pathogens. In addition to their biofilm producing ability CoNS are frequently multi-resistant, and a high prevalence of methicillin resistant CoNS is found. Staphylococcus haemolyticus is an emerging cause of nosocomial infections, primarily ...

    • Coagulase-negative staphylococci in southern brazil: Looking toward its high diversity 

      de Oliveira, Caio Fernando; Cavanagh, Jorunn Pauline; Fredheim, Elizabeth G Aarag; Reiter, Keli Cristine; Rieger, Alexandre; Klingenberg, Claus; D'Azevedo, Pedro Alves; Sollid, Johanna U Ericson (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-05)
      Introduction: Coagulase-negative staphylococci (CoNS) are the most prevalent pathogens in nosocomial infections and may serve as a reservoir of mobile genetic elements such as the staphylococcal cassette chromosome mec (SCCmec) encoding methicillin resistance. Molecular characterization of SCCmec types combined with advanced molecular typing techniques may provide essential information for ...

    • Coating of neutral liposomes with hydrophobically modified hydroxyethyl cellulose. The influence of hydrophobic chain length on the liposomes' properties and stability. 

      Grønvold, Marthe Karoline (Master thesis; Mastergradsoppgave, 2014-05-20)
      In this study, gel phase (DPPC) and liquid phase (soy PC) neutral liposomes were coated with hydrophobically modified hydroxyethyl cellulose (HM-HEC). The chain lengths of the hydrophobic moieties of HM-HEC were C8 and C16. The influence of the hydrophobic chain length of the polymer coating on the release of a fluorescence marker was studied at both 35 °C and 4 °C. I addition the size, zeta ...

    • Cochrane Collaboration Systematic Reviews may be based on trials not approved by a research ethics committee 

      Jokstad, Asbjørn (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-10-27)
      Systematic reviews (SR) may potentially contain reports of primary trials with ethical problems. The Cochrane Collaboration SRs are considered as the highest standard in evidence-based health care resources. All SRs completed during the last 5 years (2013–2017) under the management of the Oral Health Group of the Cochrane Collaboration were identified. All primary trials included in the Oral Health ...

    • Coding variants in RPL3L and MYZAP increase risk of atrial fibrillation 

      Thorolfsdottir, Rosa B; Sveinbjornsson, Gardar; Sulem, Patrick; Nielsen, Jonas B.; Jonsson, Stefan; Halldorsson, Gisli H; Melsted, Pall; Ivarsdottir, Erna V; Davidsson, Olafur B; Kristjansson, Ragnar P; Thorleifsson, Gudmar; Helgadottir, Anna; Gretarsdottir, Solveig; Norddahl, Gudmundur; Rajamani, Sridharan; Torfason, Bjarni; Valgardsson, Atli S; Sverrisson, Jon T.; Tragante, Vinicius; Holmen, Oddgeir Lingaas; Asselbergs, Folkert W; Roden, Dan M; Darbar, Dawood; Pedersen, Terje Rolf; Sabatine, Marc S.; Willer, Cristen J.; Løchen, Maja-Lisa; Halldorsson, Bjarni V; Jonsdottir, Ingileif; Hveem, Kristian; Arnar, David O; Thorsteinsdottir, Unnur; Gudbjartsson, Daniel F.; Holm, Hilma; Stefansson, Kari (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-12)
      Most sequence variants identified hitherto in genome-wide association studies (GWAS) of atrial fibrillation are common, non-coding variants associated with risk through unknown mechanisms. We performed a meta-analysis of GWAS of atrial fibrillation among 29,502 cases and 767,760 controls from Iceland and the UK Biobank with follow-up in samples from Norway and the US, focusing on low-frequency coding ...

    • Coeliac disease – what do dental health personnel know? 

      Storvolleng, Erlend Mikal Trolie; Blix Christensen, Lene (Master thesis; Mastergradsoppgave, 2019-05-18)
      Introduction: This master thesis investigates the knowledge which dental health personnel possesses regarding the correlation between coeliac disease and oral health, and the factors that may influence this knowledge. Material and methods: A questionnaire have been sent out to all dentists and dental hygienists employed in the public dental service in Nordland and Troms. One hundred and forty-three ...