Purpose: 3-Methylcrotonyl-CoA carboxylase deficiency (MCCD) is an autosomal recessive disorder of leucine catabolism that has a highly variable clinical phenotype, ranging from acute metabolic acidosis to nonspecific symptoms such as developmental delay, failure to thrive, hemiparesis, muscular hypotonia, and multiple sclerosis. Implementation of newborn screening for MCCD has resulted in broadening ...

Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune response associated with immunological memory, provided they display sufficient antigenicity and adjuvanticity. Moreover, multiple intracellular and microenvironmental features determine the propensity of RCD to drive adaptive immunity. Here, we provide an updated operational definition of immunogenic cell death ...

In March 2020, the Norwegian authorities decided to shut down the country to prevent the spread of the COVID-19 virus. The lockdown of society resulted in many healthcare workers having to close their practice or comply with a requirement of two meters distance between patients and providers, and consultations of a maximum of 15 minutes. This also applied to the CAM providers. In collaboration with ...

Radiation to the carotid arteries, e.g. in the context of head and neck cancer treatment, is one of several risk factors for artery stenosis. In principle, this fact may also have implications for stereotactic cervical spine radiotherapy, because long-term survival can be achieved in patients with oligometastatic disease and favorable prognostic features. Here, we suggest that radiation dose ...

Through coming alongside a Sami family, we open spaces to contemplate multiple forms of silence. We argue that rather than the antithesis to narrative, silence is an integral part of narrative inquiry. As narrative inquirers we need to be wakeful to what is told and also untold, often simultaneously. We believe that narrative inquiry is not necessarily about breaking silences, but it is also about ...

Colombia has been through five decades of civil war and unrest between the state and guerrilla groups and is currently in the process of healing. Several measures have been taken to aid the peace process, one of them being the Colombian-Norwegian cooperation Rural Health for Peace (RHfP) that aims to strengthen primary health care (PHC) in the areas most afflicted by the war. A previous study done ...

During their lifetimes, the current cohort of elderly Sami in Norway witnessed tremendous social changes regarding the situation of the Sami people. The overall aim of the study was to explore how elderly Sami’s experiences of health and identity in old age are worked and expressed in the stories they tell about their lives. The thesis is based on a discourse analysis of Norwegian policy documents ...

This discussant’s response to the collected articles on the consumer behavior of sharing draws on a 1983–99 record of research on the psychology of ownership and property. The major recommendations here are: (1) that sharing be defined as the simultaneous or sequential use of an object (e.g., car), a space (e.g., living room), or an intangible (e.g., identity) by more than one individual; (2) that ...

Background: Prospective studies have consistently reported lower colorectal cancer risks associated with higher intakes of total dairy products, total milk and dietary calcium. However, less is known about whether the inverse associations vary for individual dairy products with differing fat contents. Materials and Methods: In the European Prospective Investigation into Cancer and Nutrition (EPIC), ...