Browsing Det helsevitenskapelige fakultet by Title

Now showing items 2892-2911 of 10152

    • Enactive explorations of children's sensory-motor play and therapeutic handling in physical therapy 

      Håkstad, Ragnhild B.; Øberg, Gunn Kristin; Girolami, Gay L.; Dusing, Stacey C (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-11)
      Introduction: In pediatric physical therapy, there is an ongoing debate about the use of therapeutic handling and its potential effects on motor learning. In this study, we build on enactive theoretical perspectives to explore the role of therapeutic handling in connection to children's sensory-motor play, engagement, and performance during a single physical therapy session.<p> <p>Material and ...

    • Encephalitis and aseptic meningitis: short-term and long-term outcome, quality of life and neuropsychological functioning 

      Paulsen, Else Quist; Ormaasen, Vidar; Kran, Anne-Marte Bakken; Dunlop, Oona Borghild; Ueland, Per Magne; Ueland, Thor; Eikeland, Randi; Aukrust, Pål; Nordenmark, Tonje Haug (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-06)
      For those surviving encephalitis, the influence on daily life of patients and their relatives may be substantial. In contrast, the prognosis after aseptic meningitis (ASM) is considered good. In this prospective study in patients with encephalitis (n = 20) and ASM (n = 46), we show that both groups experienced reduced Health Related Quality of Life (HRQoL) at two months after discharge, and that ...

    • Endocrine-related factors and risk of venous thromboembolism 

      Lerstad, Gunhild (Doctoral thesis; Doktorgradsavhandling, 2017-05-31)
      Even though many environmental and inherited predisposing factors have been associated with venous thromboembolism (VTE), still 30–50% of the events have no obvious provoking factors. There is limited knowledge concerning the association between endocrine-related factors and VTE risk. Therefore we aimed to investigate the relation between hyperglycemia, thyroid function, vitamin D, calcium, ...

    • Endogenous Circulating Sex Hormone Concentrations and Colon Cancer Risk in Postmenopausal Women: a Prospective Study and Meta-Analysis 

      Mori, Nagisa; Keski-Rahkonen, Pekka; Gicquiau, Audrey; Rinaldi, Sabina; Dimou, Niki; Harlid, Sophia; Harbs, Justin; Van Guelpen, Bethany; Aune, Dagfinn; Cross, Amanda J.; Tsilidis, Konstantinos K.; Severi, Gianluca; Kvaskoff, Marina; Fournier, Agnès; Kaaks, Rudolf; Fortner, Renée Turzanski; Schulze, Matthias B.; Jakszyn, Paula; Sánchez, Maria-José; Colorado-Yohar, Sandra M.; Ardanaz, Eva; Travis, Ruth; Watts, Eleanor L.; Masala, Giovanna; Krogh, Vittorio; Tumino, Rosario; Sacerdote, Carlotta; Panico, Salvatore; Buenode-Mesquita, bas; Gram, Inger Torhild; Waaseth, Marit; Gunter, Marc J.; Murphy, Neil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-09-28)
      Background - Observational studies have consistently reported that postmenopausal hormone therapy use is associated with lower colon cancer risk, but epidemiologic studies examining the associations between circulating concentrations of endogenous estrogens and colorectal cancer have reported inconsistent results.<p> <p>Methods - We investigated the associations between circulating concentrations ...

    • Endogenous IL-1 receptor antagonist restricts healthy and malignant myeloproliferation 

      Villatoro, Alicia; Cuminetti, Vincent; Bernal, Aurora; Torroja, Carlos; Cossío, Itziar; Benguría, Alberto; Ferré, Marc; Konieczny, Joanna; Vázquez, Enrique; Rubio, Andrea; Utnes, Peter Andree; You, Xiaona; Fenton, Christopher Graham; Paulssen, Ruth H; Zhang, Jing; Sánchez-Cabo, Fatima; Dopazo, Ana; Vik, Anders; Anderssen, Endre; Hidalgo, Andres; Arranz, Lorena (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-03)
      Here we explored the role of interleukin-1β (IL-1β) repressor cytokine, IL-1 receptor antagonist (IL-1rn), in both healthy and abnormal hematopoiesis. Low IL-1RN is frequent in acute myeloid leukemia (AML) patients and represents a prognostic marker of reduced survival. Treatments with IL-1RN and the IL-1β monoclonal antibody canakinumab reduce the expansion of leukemic cells, including CD34+ ...

    • Endokarditt i Nord-Norge 2016-2017. Pasienter innlagt på sykehus i Nord-Norge med infeksiøs endokarditt 

      Skåland, Sindre (Master thesis; Mastergradsoppgave, 2020-08-31)
      <p>Bakgrunn: I 2016 ble Nordnorsk Kvalitetsregister for Endokarditt etablert. Pasienter innlagt på sykehus i Helse Nord regionale helseforetak med diagnosen infeksiøs endokarditt blir registrert fortløpende i registeret. Data fra 2016-2017 ble hentet ut fra dette registeret og analysert for å beskrive pasientene med hensyn til insidens, mortalitet, kliniske karakteristika, diagnostikk og behandling. ...

    • Endometrial receptivity in women of advanced age: an underrated factor in infertility 

      Pathare, Amruta D.S.; Loid, Marina; Saare, Merli; Gidlöf, Sebastian Brusell; Esteki, Masoud Zamani; Acharya, Ganesh Prasad; Peters, Maire; Salumets, Andres (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-19)
      BACKGROUND Modern lifestyle has led to an increase in the age at conception. Advanced age is one of the critical risk factors for female-related infertility. It is well known that maternal age positively correlates with the deterioration of oocyte quality and chromosomal abnormalities in oocytes and embryos. The effect of age on endometrial function may be an equally important factor influencing ...

    • Endometriehyperplasi : et litteraturstudium 

      Knai, Anette Strandlie (Master thesis; Mastergradsoppgave, 2013-05-15)
      Dette er et litteraturstudium om endometriehyperplasi. Formålet med oppgaven er å belyse de ulike aspektene ved endometriehyperplasi ettersom det er et økende problem og dermed et tema det er viktig å få et større fokus på. Det en økende forekomst av endometriecancer, og ettersom endometriehyperplasi er et forstadie til cancer, så er også dette et økende problem. Ved å ha et større fokus på diagnostikk ...

    • Endometriehyperplasi. Prognostisk bildeanalyse 

      Ludvigsen, Elisabeth; Holte, Eirin (Master thesis; Mastergradsoppgave, 2005-08)

    • Endoscopic full-thickness dissection (EFTD) in the rectum: a case series 

      Rushfeldt, Christian; Nordbø, M.; Steigen, Sonja Eriksson; Dehli, Trond; Gjessing, Petter Fosse; Norderval, Stig (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-28)
      Background Rectal endoscopic full- thickness dissection (EFTD) using a fexible colonoscope is an alternative to the wellestablished trans-anal endoscopic microsurgery (TEM) and the trans-anal minimally invasive surgery (TAMIS) techniques for resecting dysplastic or malignant rectal lesions. This study evaluated EFTD safety by analyzing outcomes of the frst patients to undergo rectal EFTD at the ...

    • Endoscopic treatment of the Retro-trochanteric Pain Syndrome. A quality study with medium-term follow-up 

      Mikkelsen, Eirik (Master thesis; Mastergradsoppgave, 2018-06-03)
      Introduction. Retro-trochanteric pain syndrome (RTPS) is a condition characterized by pain and tenderness in the buttock region. Normally sciatica originates from pathology in the spine. In RTPS the pathology resulting in sciatica is localized in the buttock region. First line treatment for RTPS is physiotherapy. This study evaluate treatment of RTPS by endoscopic bursectomy and microtenotomy ...

    • Endoskopisk behandling av gastroøsofageal reflukssykdom 

      Melby, Tiril (Master thesis; Mastergradsoppgave, 2007)
      Bakgrunn Gastroøsofageal reflukssykdom (GØRS) regnes for å være en folkesykdom, ca. 10 % av befolkningen har behandlingstrengende plager. Det er tre ulike behandlingsalternativer for denne sykdommen; kostholds- og livsstilsråd, medikamenter og kirurgi. De siste årene har det kommet flere nye alternativer, såkalte endoskopiske metoder. De ulike metodene baserer seg på termisk intervensjon, suturering ...

    • The Endothelial Cell Response to Inflammation, the Functional Role of the Endothelial-enriched Protein KANK3 and the Adipose Tissue Transcriptome 

      Struck, Eike Christopher (Doctoral thesis; Doktorgradsavhandling, 2023-10-25)
      <p>A compilation of three complementary projects explores various facets of endothelial cell biology and transcriptomics, illuminating the intricate dynamics underlying cellular responses to specific stimuli across different tissues. <p>The first project examines how endothelial cells react to the inflammatory molecule tumour necrosis factor (TNF), by studying these cells over time after TNF ...

    • Endothelial function after pancreas transplantation - A single-center observational study 

      Nordheim, Espen; Dahle, Dag Olav; Strøm Halden, Thea Anine; Birkeland, Kåre I.; Åsberg, Anders; Hartmann, Anders; Horneland, Rune; Jenssen, Trond Geir (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-06)
      <i>Background</i> - Patients with diabetes mellitus treated with successful pancreas transplantation (PTX) normalize hyperglycemia, but are exposed to immunosuppressive drugs that may impair endothelial function. This study aimed to evaluate endothelial function in single PTX recipients.<p><p> <i>Methods</i> - Flow‐mediated dilatation (FMD) in the brachial artery was measured by ultrasound 8 weeks ...

    • Endothelin-1 stimulates human monocytes in vitro to release TNF-α, IL-1β and IL-6 

      Helset, E.; Sildnes, T.; Seljelid, R.; Konopski, Z. S. (Journal article; Tidsskriftartikkel; Peer reviewed, 1993-09-09)
      INCREASED plasma- and tissue levels of endothelin-1 (ET-1) during inflammatory diseases, have suggested a role of ET-1 in the pathophysiology of inflammatory reactions. The authors have studied the effect of ET-1 on cytokine release from monocytes and monocyte-derived macrophages. ET-1 increased secretion of TNF-α, IL-1β and IL-6 in a dose- and time-dependent manner. Optimal ET-1 concentration ...

    • Endothelin-1 Stimulates Monocytes in vitro to Release Chemotactic Activity Identified as Interleukin-8 and Monocyte Chemotactic Protein-1 

      Helset, E.; Sildnes, T.; Konopski, Z. S. (Journal article; Tidsskriftartikkel; Peer reviewed, 1994)
      In the present study we examined whether endothelin-1 stimulation of human monocytes causes release of chemotactic factors. It was found that monocytes released neutrophil- and monocyte-chemotactic activity in a dose- and time-dependent manner in response to ET-1. ET-1 did not show any chemotactic activity by itself. NCA was detected in monocyte supernatants in response to ET-1 (0.01–100 nM) after ...

    • Endotoxin removal in septic shock with the Alteco LPS Adsorber was safe but showed no benefit compared to placebo in the double-blind randomized controlled trial - the Asset Study 

      Lipcsey, Miklos; Tenhunen, Jyrki; Pischke, Soeren; Kuitunen, Anne; Flaatten, Hans; De Geer, Lina; Sjölin, Jan; Frithiof, Robert; Chew, Michelle S.; Bendel, Stepani; Kawati, Rafael; Larsson, Anders; Mollnes, Tom Eirik; Tønnessen, Tor Inge; Rubertsson, Sten (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08)
      <i>Purpose</i>: Lipopolysaccharides (LPS) are presumed to contribute to the inflammatory response in sepsis. We investigated if extracorporeal Alteco LPS Adsorber for LPS removal in early gram-negative septic shock was feasible and safe. Also, effects on endotoxin level, inflammatory response, and organ function were assessed.<br><br> <i>Methods</i>: A pilot, double-blinded, randomized, Phase ...

    • Endovaskulær behandling av abdominale aortaaneurismer 

      Eriksen, Line; Johnsen, Liv-Hege (Master thesis; Mastergradsoppgave, 2002)

    • Endring av angst/depresjon hos ungdom i Finnmark over tid 

      Bye, Ronja Sæterhaug (Master thesis; Mastergradsoppgave, 2016-05-31)
      Temaet for denne oppgaven er endring i angst og depresjon hos ungdom i Finnmark over 20 år. Grunnlaget for oppgaven er to spørreundersøkelser om videregående skoleelevers psykiske helse gjennomført med 20 års mellomrom. Undersøkelsene dreide seg bl.a. om sosiodemografiske faktorer, psykisk helse, og atferd. Samsvarende variabler fra undersøkelsene ble selektert, med hovedfokus på faktorer som kan ...

    • Endring av celleproliferasjonsmarkøren Ki-67 ved strålingsterapi av kolorektal cancer 

      Jervan, Øyvind (Master thesis; Mastergradsoppgave, 2008-09-15)
      I 2005 fikk 1727 mennesker i norge diagnosen kreft i kolon eller rektum/anus. Bedre operasjonsteknikker og adjuvant behandling i form av kjemoterapi og strålebehandling har gitt færre residiv og betydelig bedre prognose. Men pasienter responderer forskjellig på strålebehandlingen, og den kan gi alvorlige bivirkninger i form av mucositt, nerveskade og sekundær kreft. Derfor er det ønskelig å kunne ...