We investigated if a five-year supervised exercise intervention with moderate-intensity continuous training (MICT) or high-intensity interval training (HIIT) versus control; physical activity according to national guidelines, attenuated the growth of white matter hyperintensities (WMH). We hypothesized that supervised exercise, in particular HIIT, reduced WMH growth. Older adults from the general ...

Follow-up studies have shown that 20-30% of patients with eating disorders develop longstanding symptoms seriously impairing their daily life. There are very few studies on the course of these patients. <br>This dissertation consists of three papers on patients admitted to a specialized inpatient treatment program at the Modum Bad psychiatric hospital. The participants were assessed upon admission, ...

Little is known about the perspectives of young people suffering from medically unexplained symptoms. This study aims to explore the experiences and strategies of young Norwegians related to incipient and persistent health complaints affecting everyday life functioning. The study draws on field notes, video material and interview transcripts from a multi-sited ethnographic study of healthcare services ...

Using <i>Caenorhabditis elegans</i> as an infection host model for <i>Vibrio cholerae</i> predator interactions, we discovered a bacterial cytotoxin, MakA, whose function as a virulence factor relies on secretion via the flagellum channel in a proton motive force-dependent manner. The MakA protein is expressed from the polycistronic <i>makDCBA</i> (<i>m</i>otility-<i>a</i>ssociated <i>k</i>illing ...

<i>Background:</i> - Norway is interested in implementing remote patient monitoring (RPM) within primary health services. This systematic review will first identify the types of RPM that are of interest to Norwegian health authorities, then synthesize the effects of RPM on clinical health and health service utilization outcomes among adults with chronic diseases.<p> <p><i>Methods:</i> - We will ...

<p>Background: Dental caries is the most prevalent non-communicable health condition globally. The surface-based susceptibility hierarchy indicates that surfaces in the same group have similar susceptibility to caries, where the most susceptible group consists of occlusal surfaces of first molars and buccal surfaces of lower first molars, and the least susceptible surfaces are smooth and proximal ...

Per and polyfluoroalkyl substances (PFASs) are persistent organic pollutants (POPs) and more than 4000 different PFASs can be found today. They are used in several industrial applications (greaseproof paper, firefighting foam, stain repellents) because of their hydrophobic and lipophobic characteristics. PFOS (a perfluoroalkyl sulfonic acid (PFSA)) and PFOA (a perfluoroalkyl carboxylic acid (PFCA)) ...

Hensikten med studien er å skaffe tilveie økt kunnskap om pårørende sine erfaringer når en ektefelle eller forelder med demenssykdom må flytte fra skjermet til somatisk sykehjemsavdeling. Tema av interesse for studien har vært om forandring av bosted påvirker rollen som pårørende og pårørende sin livssituasjon og hverdagsliv. En kvalitativ tilnærming med semi strukturerte intervju ble brukt i studien. ...

Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder caused by a CGG-repeat expansion in the 5′ UTR of the FMR1 gene on the X-chromosome. Both elevated levels of the expanded FMR1 mRNA and aberrant expression of a polyglycine protein (FMRpolyG) from the CGG-repeat region are hypothesized to trigger the pathogenesis of FXTAS. While increased expression of FMRpolyG leads ...