Bakgrunn: Importfeber er et økende problem som vokser i takt med nordmenns reisevaner. Flere av diagnosene som opptrer som importfeber er sjeldne her til lands og kan være vanskelig å oppdage rett og slett fordi de ikke står i tankene. Vi ville derfor finne ut hvor mange slike tilfeller som finnes og hvor godt de takles ved UNN. Vi ville også finne ut av hvilke diagnostiske og behandlingsmessige ...

Chronic wounds are today representing a major challenge in global healthcare due the difficulty to treat as well as the costs for the society. Therefore, improving chronic wound therapy is an urgent need. Curcumin, a polyphenol compound, has shown to have potential in wound therapy due to its anti-inflammatory, anti-infectious and anti-oxidant properties. However, the poor water solubility, low ...

Background: Atrial fibrillation (AF) is associated with increased mortality and morbidity, including risk for cerebral macro- and microinfarctions and cognitive decline, even in the presence of adequate oral anticoagulation. AF is strongly related to increased inflammatory activity whereby anti-inflammatory agents can reduce the risk of new or recurrent AF. However, it is not known whether ...

Traumatic spinal cord injury is an injury which affect the patient on a functional, mental, social and economic level (1, 2). An injury to the spinal cord can affect motor, sensory and autonomic systems (1). From injury through rehabilitation process, neurologic recovery is seen (3). Hence it is interesting to find out what already is known about neurologic recovery in SCI and find what to expect ...

Objective: Evidence-based personality disorder (PD) treatments are dominated by interventions targeting Borderline PD, although clinical populations characteristically include different PD features and severity. Personality functioning is a new concept intended to capture common features across PDs. This study aimed to investigate longitudinal improvement of personality functioning in a clinical ...

In 2009 stroke care in the University Hospital of Northern Norway was reorganized. Until that year the hospital provided stroke care in two separate locations: patients 75 years and older were treated in the Geriatric Unit of the Medical Department while those younger were treated in the Neurological Department. Waiting times in the emergency unit were long, especially for the older patients. With ...

Background: Matching treatment based on tumour molecular characteristics has revolutionized the treatment of some cancers and has given hope to many patients. Although personalized cancer care is an old concept, renewed attention has arisen due to recent advancements in cancer diagnostics including access to high-throughput sequencing of tumour tissue. Targeted therapies interfering with cancer ...

Objectives: Machine learning (ML) and natural language processing have great potential to improve effciency and accuracy in diagnosis, treatment recommendations, predictive interventions, and scarce resource allocation within psychiatry. Researchers often conceptualize such an approach as operating in isolation without much need for human involvement, yet it remains crucial to harness human-inthe-loop ...

Ischaemic heart disease (IHD) is a complex disorder and a leading cause of death and morbidity in both men and women. Sex, however, affects several aspects of IHD, including pathophysiology, incidence, clinical presentation, diagnosis as well as treatment and outcome. Several diseases or risk factors frequently associated with IHD can modify cellular signalling cascades, thus affecting ischaemia/reperfusion ...