<p><i>Introduction</i>: Various efforts aim to enhance continuity of care for patients with long-term health-care needs. Since 2012, Norwegian hospitals are mandated to appoint individual care coordinators for patients with complex needs to ensure continuity in the care pathway. New roles must meld with current practice. Implementation has been slow. This study investigates current care coordination ...

Selective autophagy is a catabolic process with which cellular material is specifically targeted for degradation by lysosomes. The function of selective autophagic degradation of self-components in the regulation of innate immunity is still unclear. Here we show that Drosophila Kenny, the homolog of mammalian IKKγ, is a selective autophagy receptor that mediates the degradation of the IκB kinase ...

In the absence of a medical birth registry, the official statistics are the only sources of information about pregnancy outcomes in the Republic of Sakha (Yakutia) (RS). We analysed the official statistical data about birth rate, fertility, infant and maternal mortality in the RS in the period 2003-2014. Compared with all- Russian data, the RS had a higher birth rate, especially in rural districts. ...

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been declared a global pandemic. Our goal was to determine whether co-infections with respiratory polyomaviruses, such as Karolinska Institutet polyomavirus (KIPyV) and Washington University polyomavirus (WUPyV) occur in SARS-CoV-2 infected patients. Oropharyngeal swabs from 150 individuals, 112 symptomatic COVID-19 patients and 38 ...

The present study evaluated the effect of a smaller, lighter ball on kicking speed and technical- tactical and physical match performance in high-level adult female footballers. In the laboratory test setting, the peak ball velocity was 6 % higher with the new ball (NB) than the standard ball (SB) (26.5 ± 0.5 vs. 25.1 ± 0.5 m · s − 1, p < 0.05). However, during match-play, no differences ...

Immune aggregates organized as tertiary lymphoid structures (TLS) are observed within the kidneys of patients with systemic lupus erythematosus and lupus nephritis (LN). Renal TLS was characterized in lupus-prone New Zealand black × New Zealand white F1 mice analyzing cell composition and vessel formation. RNA sequencing was performed on transcriptomes isolated from lymph nodes, macrodissected TLS ...

In these studies, we focus on moricrase (enzyme mixture from hapatopancreas of king crab) as an activator of inflammatory responses in airway cells. Taking under consideration that serine proteases, such as trypsin, are stimulator of interlukin-8 (IL-8). We investigate the role of protease activated receptor 2 (PAR-2) in the inflammation of human pulmonary epithelial cells (A549). A549 cells were ...

Child abuse and neglect are common problems across the world that result in negative consequences for children, families and communities. Children who have been abused or neglected are often removed from the home and placed in residential care or with other families, including foster families. Foster care was traditionally provided by people that social workers recruited from the community specifically ...

Studien er en retrospektiv undersøkelse pasienter med ikke-småcellet lungekreft (NSCLC) som fikk kirurgisk behandling for sin sykdom ved Universitetssykehuset i Nord-Norge i Tromsø i perioden 1996 til 2003.