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The Role of Stroke as a Trigger for Incident Venous Thromboembolism: Results from a Population-based Case-Crossover Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-22)Stroke is associated with a short-term increased risk of subsequent venous thromboembolism (VTE). It is unclear to what extent this association is mediated by strokerelated complications that are potential triggers for VTE, such as immobilization and infection. We aimed to investigate the role of acute stroke as a trigger for incident VTE while taking other concomitant VTE triggers into account. ... -
The Role of Surgery as a Trigger for Incident Venous Thromboembolism
(Master thesis; Mastergradsoppgave, 2020-08-30)Background: Venous thromboembolism (VTE) is a collective term for deep vein thrombosis and pulmonary embolism. Surgery is a major and well-established transient risk factor (i.e. trigger) for VTE in the general population. However, the impact of major surgery on the risk of VTE has not been thoroughly investigated when other concomitant VTE triggers are also taken into account. Aim: The aim of ... -
Role of the Complement System in the Pathogenesis of Venous Thromboembolism
(Doctoral thesis; Doktorgradsavhandling, 2019-04-02)Venous thromboembolism (VTE) is a common disease with serious short- and long-term complications. VTE is a collective term for deep vein thrombosis (DVT) and pulmonary embolism (PE) and is the third most common cardiovascular disease, causing significant morbidity and mortality. Despite preventive strategies, the incidence of VTE has been stable or increasing slightly during the last decades, affecting ... -
The role of the estrogen receptor α in the medial amygdala and the ventromedial nucleus of the hypothalamus in sexual motivation, social recognition, aggression and anxiety
(Doctoral thesis; Doktorgradsavhandling, 2010-09-01)Estrogens have been shown to be implicated not only in sexual behaviors but also in several cognitive functions, social behaviors, and emotional reactions. Estrogen receptors mediate estrogen actions in the brain and the estrogen receptor α (ERα) has attracted some attention. Although the display of female sexual motivation and copulatory behaviors require estrogens, their sites of action in brain ... -
Role of the mannose receptor in tumor associated macrophages. Studies in a mouse melanoma model
(Master thesis; Mastergradsoppgave, 2014-04-15)Tumor-associated macrophages (TAMs) play an important role in cancer-related inflammation. TAMs develop M2 polarization which may support tumor growth. Mannose receptor (MR) expression is a hallmark for this cell-subpopulation, and the MR has recently been suggested to be involved in TAM polarization. The aim of the study was to investigate the role of MR in TAM polarization and tumor development ... -
Role of the “differently-abled” researcher: Challenges and solutions in inclusive research
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-30)This article examines the role of the “differently-abled” researcher in facilitating inclusive research with adults (age 16 and older) with intellectual disabilities living in Sami areas of Norway. Topics discussed include challenges that may arise while conducting such research due to the nature of the project (externally-funded pre-existing project), methods applied (quantitative) and people ... -
The role of tuberculosis coinfection on lung function of HIV infected children and adolescents in Africa. A systematic review
(Master thesis; Mastergradsoppgave, 2019-06-01)Objectives: To systematically review existing literature on what role history of tuberculosis (TB) plays in lung function abnormalities and the development of chronic lung disease of HIV infected children and adolescents in Africa, as the burden of paediatric HIV and TB coinfection is the highest in this region. Methods: Systematic searches were performed in PubMed and EMBASE databases using PICO ... -
The role of ultrasonic vocalizations in the formation of rat groups in a semi-natural environment
(Master thesis; Mastergradsoppgave, 2018-05-03)This study investigated if ultrasonic vocalizations (USV) had an effect on the formation of groups of rats in a semi-natural setting that allowed the rats to live closer to their natural state in the wild. This was done by letting four groups of rats into a semi-natural environment. Where prior to release into the environment, all the rats received surgery. Where some of the rats had the nerve to ... -
Role of Virus-Induced Host Cell Epigenetic Changes in Cancer
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-03)The tumor viruses human T-lymphotropic virus 1 (HTLV-1), hepatitis C virus (HCV), Merkel cell polyomavirus (MCPyV), high-risk human papillomaviruses (HR-HPVs), Epstein-Barr virus (EBV), Kaposi’s sarcoma-associated herpes virus (KSHV) and hepatitis B virus (HBV) account for approximately 15% of all human cancers. Although the oncoproteins of these tumor viruses display no sequence similarity to one ... -
The role of Vitamin D binding protein, total and free 25-hydroxyvitamin D in diabetes
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-19)Vitamin D is important for bone health, but may also have extra-skeletal effects. Vitamin D and its binding protein DBP have immunological effects and may therefore be important in the development of type 1 diabetes (T1DM), and low serum levels of 25-hydroxyvitamin D (25(OH)D) are associated with later development of type 2 diabetes (T2DM). However, it has so far been difficult to convincingly show ... -
Roles of human papillomavirus (HPV) and human immunodeficiecyvirus (HIV) in cervix uteri cancer
(Master thesis; Mastergradsoppgave, 2002-08) -
”Rollen min ble mye viktigere enn jeg noen gang før har opplevd”. En kvalitativ studie av ergoterapistudenter i tverrfaglig studentteam
(Master thesis; Mastergradsoppgave, 2015-09-30)Tverrfaglig samarbeid er veldig aktuelt innenfor helsetjenesten, og er fastlagt i lovverk og omtalt i andre politiske dokumenter som er knyttet opp mot helsetjenesten. Hensikten med denne masteroppgaven er å belyse hva studenter som har deltatt i praksis i tverrfaglige studentteam beskriver som egen yrkesutøvelse. Tverrfaglige studentteam ble arrangert av et pilot¬prosjekt ved Universitetet i Tromsø ... -
Rollen til urokinase plasminogen aktivator reseptoren (uPAR) for uttrykk av molekyler involvert i celle adhesjon, migrasjon og invasjon
(Master thesis; Mastergradsoppgave, 2010-05-20)Urokinase-type-plasminogen activator reseptor (uPAR) er funnet overuttrykt i organer som har omfattende remodulering av vevet. uPAR har flere ligander, blant annet serine proteasen urokinase plasminogen aktivator uPA, ekstracellulær matrix proteine vitronectin og integriner. uPA aktiveres ved binding til uPAR. Aktiv uPA aktiverer ved binding til uPAR og kan deretter aktivere plasmin som kan degradere ... -
Rom for læring: En spørreundersøkelse om fysiske omgivelser, undervisningsform og studenters læring i høyere utdanning
(Mastergradsoppgave; Master thesis, 2021-12-14)Studentaktiv læring er en politisk føring, og det er et behov for tilpasning av eksisterende læringsareal, samt styrende pedagogiske prinsipper for utvikling av fremtidens design og arkitektur i høyere utdanning. Denne oppgaven undersøkte samsvaret mellom studenters opplevelse av undervisning i formelle læringsareal, deres muligheter og bruk, og studentenes rapportering av kognitive læringsutbytter. ... -
Room tilt illusion and subclavian steal - A case report
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-08)<i>Background</i> - Room tilt illusion (RTI) is a rare symptom of higher vestibular dysfunction, consisting of a transient vertical rotation of the visual scene in the sagittal or coronal plane, most often 90<sup>o</sup> or 180<sup>o</sup>, without any alteration in shape, size and color of objects.<br><br> <i>Case presentation</i> - A 63-year-old woman with a history of hypertension and chronic ... -
Rosuvastatin treatment decreases plasma procoagulant phospholipid activity after a VTE: A randomized controlled trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-25)Background - Venous thromboembolism (VTE) is a frequent cardiovascular disease with severe complications, including recurrence and death. There is a great need for alternative prophylactic treatment options as anticoagulation is accompanied by increased bleeding risk. Statins are reported to reduce the risk of incident and recurrent VTE, but the mechanisms are elusive. Procoagulant phospholipids ... -
Rotatormansjettsyndrom - hvilke konservative behandlingsformer har dokumentert effekt? - Et litteraturstudie
(Master thesis; Mastergradsoppgave, 2013-04-24)BAKGRUNN: Rotatormansjettsyndrom er den hyppigste årsaken til skuldersmerter. Årsaken bak tilstanden er multifaktoriell. Mangel på en gullstandard for diagnostikk, klassifisering, bruk av terminologi og behandlingsprotokoller for skuldersmerter gjør sammenligning av forskningsresultater problematisk. Det finnes mange behandlingsalternativer for tilstanden, men ingen kunnskapsbasert behandlingsveieleder ... -
Routine deferred computed tomography for patients with suspected urolithiasis is low-value healthcare
(Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-23)<p><i>Objective - </i>The aim of this study was to investigate the benefits of deferred routine computed tomography of the kidneys, ureters and bladder (CT KUB) for patients with a self-limiting episode of suspected urolithiasis. <p><i>Materials and methods - </i>The study comprised a case series of consecutive patients examined with deferred routine CT KUB for control of suspected urolithiasis. ... -
Rural general practice patients’ coping with hazards and harm: an interview study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-18)<i>Objective</i>: The aim of this study is to identify and analyse rural general practice patients’ experiences of hazards and harm that comprise adverse events, and their strategies for coping with them.<p> <p><i>Design</i>: Interview study using systematic text condensation and coping strategy theory in an abductive analysis process.<p> <p><i>Setting</i>: Nine rural general practice clinics ... -
Rural general practice staff experiences of patient safety incidents and low quality of care in Norway: an interview study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-06-28)Background and objectives: General practitioners (GPs), nurses and medical secretaries (practice staff) are responsible for the continuous provision of safe care in rural general practice. Little is known about their role in situations where patients were or could have been harmed in a rural setting. Therefore, we sought to investigate rural general practice staff experiences of patient safety ...
