Viser treff 9486-9505 av 10098

    • Tumour-suppressor microRNAs let-7 and mir-101 target the proto-oncogene MYCN and inhibit cell proliferation in MYCN-amplified neuroblastoma 

      Buechner, Jochen; Tømte, Ellen; Haug, Bjørn Helge; Henriksen, Jørn Remi; Løkke, Cecilie; Flægstad, Trond; Einvik, Christer (Journal article; Tidsskriftartikkel; Peer reviewed, 2011-06-07)
      BACKGROUND: MicroRNAs (miRNAs) regulate expression of many cancer-related genes through posttranscriptional repression of their mRNAs. In this study we investigate the proto-oncogene MYCN as a target for miRNA regulation.<p> <p>METHODS: A luciferase reporter assay was used to investigate software-predicted miRNA target sites in the 30 -untranslated region (30 UTR) of MYCN. The miRNAs were ...
    • Tuning of Liver Sieve: The Interplay between Actin and Myosin Regulatory Light Chain Regulates Fenestration Size and Number in Murine Liver Sinusoidal Endothelial Cells 

      Zapotoczny, Barlomiej; Szafranska, Karolina; Lekka, Malgorzata; Ahluwalia, Balpreet Singh; McCourt, Peter Anthony (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-08-30)
      Liver sinusoidal endothelial cells (LSECs) facilitate the efficient transport of macromolecules and solutes between the blood and hepatocytes. The efficiency of this transport is realized via transcellular nanopores, called fenestrations. The mean fenestration size is 140 ± 20 nm, with the range from 50 nm to 350 nm being mostly below the limits of diffraction of visible light. The cellular ...
    • Turnover of IPS employment specialists: Rates and predictors 

      Butenko, Daniil; Rinaldi, Miles; Brinchmann, Beate; Killackey, Eoin; Johnsen, Erik; Mykletun, Arnstein (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-15)
      BACKGROUND: There are anecdotal reports of high job turnover of Individual Placement and Support employment specialists. However, no studies have addressed this issue.<p> <p>OBJECTIVE: To explore whether turnover rates among employment specialists are higher compared to public sector employees along with the correlates of turnover intentions. <p>METHODS: A repeated cross-sectional study collected ...
    • Turnuslegers erfaringer med veiledning i turnustjenesten 

      Haugdahl, Hege Selnes; Vikan, Astri; Bjerkeset, Ottar; Hamran, Torunn (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      Den nasjonale spørreundersøkelsen blant turnusleger fra 2007-2008 viste at veiledningen ved sykehuset Levanger var mangelfull. Formålet med denne kvalitative studien var derfor å få en bedre forståelse av turnuslegers erfaringer med veiledning i turnustjenesten. Kvalitative intervju av syv turnusleger som hadde gjennomført turnustjeneste ved sykehuset Levanger i 2007-2008. Erfaringene ble analysert ...
    • Tvang og makt eller normalisering? Ja takk - begge deler. 

      Stavem, Sonja (Master thesis; Mastergradsoppgave, 2011-05-18)
      Bruk av tvang og makt under utøvelsen av sosiale tjenester for mennesker med psykisk utviklingshemming er regulert i kap. 4A i sosialtjenesteloven. Loven ble første gang tatt i bruk som en prøvelov i 1999, og har siden 2004 vært en permanent lov; kap. 4A i Lov om sosiale tjenester. Hvilket syn på mennesker med psykisk utviklingshemming, og hvilken problemforståelse er det som ligger til grunn for ...
    • Tvangshjemler kan føre til mer tvang 

      Riley, Henriette; Storvik, Marius; Hansen, Thomas (Journal article; Tidsskriftartikkel, 2023-03-03)
      En praksis med bruk av tepper, bandasjer, borrelåsstropper eller lignende for å sikre pasienter som motsetter seg under transport, kan være svært inngripende – og gir grunn til bekymring.
    • Tvangsinnleggelser ved en psykiatrisk avdeling, Universitetssykehuset i Nord-Norge 

      Vågan, Audun F. (Master thesis; Mastergradsoppgave, 2002-09)
    • Tverrfaglig poliklinisk behandling av sykelig overvekt 

      Olaisen, Sindre Hellum (Master thesis; Mastergradsoppgave, 2011-09)
      Bakgrunn: Overvektsepidemien skrider frem og rammer stadig flere over hele verden. Verdens helseorganisasjon har innsett alvoret og laget en plan for å forebygge livsstilssykdommer. Det norske Helse- og omsorgsdepartementet har pålagt helseregionene å etablere behandlingstilbud for pasienter med helseproblemer som følge av uttalt overvekt og fedme, og Senter for sykelig overvekt ved Universitetssykehuset ...
    • Tverrprofesjonell praksis utfordrer samarbeidet mellom helsefagstudenter 

      Norbye, Bente (Chapter; Bokkapittel, 2020)
      Dette kapittelet vil synliggjøre studenters erfaringer fra tverrprofesjonell praksis i et aksjonsforskningsprosjekt gjennomført i perioden 2014–2016. Prosjektet hadde som overordnet mål å etablere nye tverrfaglige praksisformer i samarbeid mellom utvalgte helsetjenester og fire profesjonsutdanninger. Prosjektet ble gjennomført i regi av Forskningsgruppa for profesjonsutdanning ved Institutt for helse ...
    • Tverrprofesjonell praksis, læring og samarbeid – forståelse av egen og andres rolle i læringsprosessen 

      Cheetham, Nina Bøhle (Chapter; Bokkapittel, 2020)
      Arbeidet med å implementere nye arenaer for tverrprofesjonell praksis er under stadig utvikling og gjenstand for omfattende forskning. I dette kapittelet diskuterer jeg tverrprofesjonell samarbeidslæring (TPS) i utdanning av helsefagstudenter. Ved hjelp av datamateriale fra to tverrprofesjonelle prosjekter, ett i en barneavdeling og ett i to distriktskommuner, utforskes medisin- og sykepleierstudenters ...
    • Tweet content related to sexually transmitted diseases: No joking matter 

      Gabarron, Elia; Serrano, Artur; Wynn, Rolf; Lau, Annie Y.S. (Journal article; Tidsskriftartikkel; Peer reviewed, 2014-10-06)
      Online social media, such as the microblogging site Twitter, have become a space for speedy exchange of information regarding sexually transmitted diseases (STDs), presenting a potential risk environment for how STDs are portrayed. Examining the types of “tweeters” (users who post messages on Twitter) and the nature of “tweet” messages is important for identifying how information related to STDs is ...
    • Twenty years with teledermatology in North Norway 

      Ali, Md. Eunus (Master thesis; Mastergradsoppgave, 2008-05-15)
      ‘A picture is worth more than a thousand words’ - (Mann & Colven, University of Washington Medical School), that simply can justify the necessity of teledermatology. In this paper, five information technology (IT) efforts in the field of teledermatology that based on skin image transmission procedure and their historical transformations in context of the notions of information infrastructures and ...
    • Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia 

      McMaster, Mary L.; Berndt, Sonja I.; Zhang, Jianqing; Slager, Susan L.; Li, Shengchao Alfred; Vajdic, Claire M.; Smedby, Karin E.; Yan, Huihuang; Birmann, Brenda M.; Brown, Elizabeth E.; Smith, Alex; Kleinstern, Geffen; Fansler, Mervin M.; Mayr, Christine; Zhu, Bin; Chung, Charles C.; Park, Ju-Hyun; Burdette, Laurie; Hicks, Belynda D.; Hutchinson, Amy; Teras, Lauren R.; Adami, Hans Olov; Bracci, Paige M.; McKay, James; Monnereau, Alain; Link, Brian K.; Vermeulen, Roel C.H.; Ansell, Stephen M.; Maria, Ann; Diver, W. Ryan; Melbye, Mads; Ojesina, Akinyemi I.; Kraft, Peter; Boffetta, Paolo; Clavel, Jacqueline; Giovannucci, Edward; Besson, Caroline M.; Canzian, Federico; Travis, Ruth C.; Vineis, Paolo; Weiderpass, Elisabete; Montalvan, Rebecca; Wang, Zhaoming; Yeager, Meredith; Becker, Nikolaus; Benavente, Yolanda; Brennan, Paul; Foretova, Lenka; Maynadie, Marc; Nieters, Alexandra; de Sanjose, Silvia; Staines, Anthony; Conde, Lucia; Riby, Jacques; Glimelius, Bengt; Hjalgrim, Henrik; Pradhan, Nisha; Feldman, Andrew L.; Novak, Anne J.; Lawrence, Charles; Bassig, Bryan A.; Lan, Qing; Zheng, Tongzhang; North, Kari E.; Tinker, Lesley F.; Cozen, Wendy; Severson, Richard K.; Hofmann, Jonathan N.; Zhang, Yawei; Jackson, Rebecca D.; Morton, Lindsay M.; Purdue, Mark P.; Chatterjee, Nilanjan; Offit, Kenneth; Cerhan, James R.; Chanock, Stephen J.; Rothman, Nathaniel; Vijai, Joseph; Goldin, Lynn R.; Skibola, Christine F.; Caporaso, Neil E. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-10)
      Waldenström macroglobulinemia (WM)/lymphoplasmacytic lymphoma (LPL) is a rare, chronic B-cell lymphoma with high heritability. We conduct a two-stage genome-wide association study of WM/LPL in 530 unrelated cases and 4362 controls of European ancestry and identify two high-risk loci associated with WM/LPL at 6p25.3 (rs116446171, near EXOC2 and IRF4; OR = 21.14, 95% CI: 14.40–31.03, P = 1.36 × 10<s ...
    • Two hundred years of cancer epidemiology in Norway-before and during the NOFE era 

      Gram, Inger Torhild; Lund, Eiliv (Journal article; Tidsskriftartikkel; Peer reviewed, 2015)
    • Two interventions to treat pain disorders and post-traumatic symptoms among Syrian refugees: protocol for a randomized controlled trial 

      Hasha, Wegdan; Fadnes, Lars Thore; Igland, Jannicke; Vårdal, Rolf; Giusti, Line; Strømme, Elisabeth Marie; Haj Younes, Jasmin; Heltne, Unni Marie; Kumar, Bernadette Nirmal; Diaz, Esperanza (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-27)
      <i>Background</i> - There is a high prevalence of pain and post-traumatic symptoms among refugees and feasible interventions to manage these are needed. However, knowledge about the effect of physiotherapy and psychological group interventions among refugees is scarce. Our aim is to determine whether two different interventions, the Physiotherapy Activity and Awareness Intervention (PAAI) and ...
    • A two-lab direct replication attempt of Southgate, Senju and Csibra (2007) 

      Kampis, D.; Kármán, P.; Csibra, G.; Southgate, V.; Hernik, M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-25)
      The study by Southgate et al. (2007 Psychol. Sci.18, 587–592. (doi:10.1111/j.1467-9280.2007.01944.x)) has been widely cited as evidence for false-belief attribution in young children. Recent replication attempts of this paradigm have yielded mixed results: several studies did not replicate the original findings, raising doubts about the suitability of the paradigm to assess non-verbal action prediction ...
    • A two-stage cognitive theory of the positive symptoms of psychosis. Highlighting the role of lowered decision thresholds 

      Moritz, Steffen; Pfuhl, Gerit; Luedtke, Thies; Menon, Mahesh; Balzan, Ryan P; Andreou, Christina (Journal article; Tidsskriftartikkel; Peer reviewed, 2016)
      <b>Objectives:</b> We outline a two-stage heuristic account for the pathogenesis of the positive symptoms of psychosis. <b>Methods:</b> A narrative review on the empirical evidence of the liberal acceptance (LA) account of positive symptoms is presented. <b>Hypothesis:</b> At the heart of our theory is the idea that psychosis is characterized by a lowered decision threshold, which results in ...
    • Two-year motor outcomes associated with the dose of NICU based physical therapy: The Noppi RCT 

      Øberg, Gunn Kristin; Handegård, Bjørn Helge; Campbell, Suzann K.; Ustad, Tordis; Fjørtoft, Toril Larsson; Kaaresen, Per Ivar; Girolami, Gay L. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-25)
      Background - Interventions involving both the parent and the preterm infant have demonstrated lasting effects on cognitive outcomes, but motor effects are less salient. It remains unclear when to commence early intervention and if dosages have impact on motor outcomes.<p> <p>Aims - To examine the effect on motor performance at 24-months corrected age following a parent-administered intervention ...
    • Tying mobile health tools to the users’ needs – Motivational drivers 

      Pitz, Dorothee (Master thesis; Mastergradsoppgave, 2023-05-30)
      <p>Objective: The primary aim of this thesis is to contribute novel insights into the distinctive attributes of ICT systems, with a particular emphasis on features preferred by users in the realm of mobile health (mHealth) applications and devices. The study aimed at identifying motivational factors that enhance and sustain the usage and adaption of mHealth applications, wearables, and trackers among ...