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Triggers and risk factors of first and recurrent venous thromboembolism
(Doctoral thesis; Doktorgradsavhandling, 2020-01-29)Venous thromboembolism (VTE), encompassing both deep vein thrombosis and pulmonary embolism, is a major public health concern due to substantial morbidity and mortality. Around half of all VTE cases are hospital-related. Importantly, VTE also has life-long implications, as a large proportion of VTE-patients suffer either a recurrent event or chronic complications. The first aim of the thesis was to ... -
TRIM proteins in autophagy: A study of TRIM32 and TRIM27
(Doctoral thesis; Doktorgradsavhandling, 2020-02-02)<p>TRIM proteins are ubiquitin E3 ligases known to be involved in a number of different processes in the cells, such as intracellular signaling, transcription, autophagy, innate immunity, cell cycle progression and DNA repair. Mutations and dysregulation of TRIM proteins are implicated in many diseases, and a number of TRIMs are described as both tumor suppressors and oncogenes. Furthermore, several ... -
TRIM27 is an autophagy substrate facilitating mitochondria clustering and mitophagy via phosphorylated TBK1
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-16)Tripartite motif-containing protein 27 (TRIM27/also called RFP) is a multifunctional ubiquitin E3 ligase involved in numerous cellular functions, such as proliferation, apoptosis, regulation of the NF-kB pathway, endosomal recycling and the innate immune response. TRIM27 interacts directly with TANK-binding kinase 1 (TBK1) and regulates its stability. TBK1 in complex with autophagy receptors is ... -
Triple use of autologous amnion graft in the treatment of meningomyelocele and split cord malformation
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-20)This article describes the triple use of autologous amnion graft as a new procedure in the treatment of myelomeningocele and in myelomeningocele with split cord malformation. The first amnion graft was used as a physical and mechanical barrier to protect the myelomeningocele (MMC) from desiccation and mechanical stress directly after birth. A second graft was used as a dura substitute to close the ... -
The Tromso Infant Faces Database (TIF): development, validation and application to assess parenting experience on clarity and intensity ratings
(Journal article; Tidsskriftartikkel, 2017-03-24)Newborns and infants are highly depending on successfully communicating their needs; e.g., through crying and facial expressions. Although there is a growing interest in the mechanisms of and possible influences on the recognition of facial expressions in infants, heretofore there exists no validated database of emotional infant faces. In the present article we introduce a standardized and freely ... -
The Tromsø Heart study. Population studies of coronary risk factors with special emphasis on high density lipoprotein and the family occurrence of myocardial infarction.
(Research report; Forskningsrapport, 1979) -
The Tromsø study : risk factors for non-vertebral fractures in a middle-aged population
(Doctoral thesis; Doktorgradsavhandling, 1999) -
The Tromsø Study: Fit Futures: a study of Norwegian adolescents' lifestyle and bone health
(Journal article; Tidsskriftartikkel; Peer reviewed, 2014-06-04)Summary: Bone mass achievement predicts later fracture risk. This population-based study describes bone mineral density levels (BMD) and associated factors in Norwegian adolescents. Compared with international reference ranges, BMD levels appear higher and physical activity levels are positively associated with BMD. <p>Purpose: Norway has one of the highest reported incidences of osteoporotic ... -
Tror barnehageansatte at informasjon om ryggplager bidrar til bedre håndtering av muskelskjelettlidelser? : en tverrsnittsundersøkelse
(Master thesis; Mastergradsoppgave, 2010-05-01)Bakgrunn: Prosjektet ”iBedrift” bruker arbeidsplassen som arena for forebygging av sykefravær på grunn av muskelskjelettlidelser. Hensikt: Å undersøke om ansatte som har fått informasjon gjennom prosjektet ”iBedrift” tror at informasjonen fører til en bedre håndtering av muskelskjelettlidelser. Metode: Spørreundersøkelse blant 119 barnehageansatte, der 49 respondenter deltar i ”iBedrift” og resten ... -
Truar skilnadene i tilvisingsratar målet om likeverdige helsetenester?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2011-10-04)BAKGRUNN - Sogn og Fjordane fylke har i landsmålestokk, og serleg i høve til dei andre fylka i Helse Vest, hatt eit høgt forbruk av spesialisthelsetenester. Utover det at fylket har to små lokalsjukehus, har lite vore kjent som kunne forklare det høge forbruket, og serskilt ikkje om det eksisterer kontrastar i forbruk mellom kommunane i fylket.<p> <p>MATERIALE OG METODE - Med utgangspunkt i ... -
Truncated Autonomy: Neocortical Selves, Reverse Reductionism and End-of-Life Care
(Chapter; Bokkapittel, 2016-12-29)In professional guidelines for palliative sedation in end-of life care, a particular notion of conscious life experience is associated with specific cognitivist notion of frontal lobe autonomy. Drawing on Turner and Fauconnier’s work in cognitive linguistics I argue in this chapter that even our most central notions like human subjectivity and autonomy are conceptual blends. This chapter explores ... -
Trunk control in children with cerebral palsy : a reliability study of the Trunk Impairment Scale
(Master thesis; Mastergradsoppgave, 2010-05-12)Background and objective. Standardized scales are useful for treatment planning and evaluation. The purpose of this study was to examine the reliability of the Trunk Impairment Scale (TIS) for children with cerebral palsy (CP). Design. This was an intra- and inter-observer reliability study. Methods. Video recordings of 25 children, 20 with CP and 5 with no motor impairment, in the age group 5–12 ... -
Trygg kirurgi - oppdekking og organisering av instrumentbord til operasjon: en scoping review
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-08)Bakgrunn: Oppdekking og organisering av instrumentbord er en kompleks arbeidsprosess som krever et bredt kunnskapsgrunnlag. Når kunnskapsbaserte anbefalinger tas i bruk, øker sikkerheten i operasjonsrommet. Hensikt: Studiens hensikt var å styrke utøvernes beslutningsgrunnlag. Det gjøres ved å samle, strukturere, oppsummere og presentere kunnskapsbaserte anbefalinger. <p> <p>Metode: Vi utførte en ... -
Trøst som oppmerksomt nærvær i mellommenneskelig profesjonell praksis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-30)I dette vitenskapelige essayet synliggjøres trøstens betydning i mellommenneskelige profesjonelle praksiser. Forfatterne viser gjennom to adskilte forskningsprosjekter i to ulike fagfelt, betydningen av å ha et sansene oppmerksomt nærvær i møte med mennesker som erfarer at livet er krevende eller truet grunnet sykdom eller andre eksistensielle grunnvilkår. I essayet er det trøstens fremtredelser ... -
Trøstens stille stemme i helsesykepleiekonsultasjoner
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-13)Å gi trøst er en integrert del av sykepleie, og å få trøst er et grunnleggende menneskelig behov. I dette vitenskapelige essayet ser vi nærmere på hvordan fenomenet trøst kommer til uttrykk i norsk helsesykepleiepraksis. Helsesykepleiere i Norge yter ikke pleietjenester, men tilbyr helsefremmende og forebyggende helsetjenester til barn og unge mellom 0 og 20 år. Deres omsorgspraksis har blitt beskrevet ... -
Tuberculosis : an increasing global health problem, presenting Russia as an example
(Master thesis; Mastergradsoppgave, 2011-09-15)Tuberculosis is an important global public health problem. Although increasing, the prevalence of TB in Norway is low, however the situation changes completely crossing the border to our neighbor country Russia. We wanted to learn more about management of TB, the global TB situation and the situation in Russia. -
Tuberculosis case detection by trained inmate peer educators in a resource-limited prison setting in Ethiopia: a cluster-randomised trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-26)<i>Background</i> - To improve tuberculosis case detection, interventions that are feasible with available resources are needed. We investigated whether involving trained prison inmates in a tuberculosis control programme improved tuberculosis case detection, shortened pre-treatment symptom duration, and increased treatment success in a resource-limited prison setting in Ethiopia.<p><p> <i>Me ... -
Tuberculosis in Children and Adolescence in North Norway
(Master thesis; Mastergradsoppgave, 2016-06-01)Abstract The objective of this thesis is to gain knowledge in tuberculosis in children and adolescent for ten years period from 01.01.05- 31.12.14 at the University Hospital of North Norway. The study was to answer the following questions: the number patients treated for latent and active tuberculosis in 10 years period of, the debut age for symptoms and treatment, the diagnostic methods the choice ... -
Tuberculosis in HIV positive individuals - risk factors, diagnostic methods and follow-up in a low-endemic country
(Doctoral thesis; Doktorgradsavhandling, 2015-12-09)Tuberculosis (TB) is a diagnostic challenge in persons infected with human immunodeficiency virus (HIV). Furthermore, HIV positive individuals with latent TB infection (LTBI) have the highest risk of progression to active TB. WHO initiatives to reduce the global burden of HIV/TB co-infections include better surveillance, improved diagnosis of TB in HIV patients and implementation of TB preventive ... -
Tuberculosis treatment outcome and predictors in northern Ethiopian prisons: A five-year retrospective analysis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-20)<p><i>Background</i>: The prison situations are notorious for causing interruptions of tuberculosis (TB) treatment and occurrence of unfavorable outcomes. In Ethiopian prisons, though TB treatment programs exist, treatment outcome results and factors contributing to unsuccessful outcome are not well documented. In this study, we assessed the treatment outcome of TB cases and identified risk factors ...
