Browsing Det helsevitenskapelige fakultet by Author "Issifou, Halimatu Sadia T."
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Molecular modelling of interactions between antipsychotic drugs and receptors mediating antipsychotic effects and important side effects
Issifou, Halimatu Sadia T. (Master thesis; Mastergradsoppgave, 2021-05-10)Dopamine and serotonin are two neurotransmitters that exert their actions through mediation of dopaminergic and serotonergic receptors respectively. The receptors in focus in the current study, are the dopamine D2 and serotonin 5-HT2A receptors. Common for both receptors is that they are class A G-protein-coupled receptors consisting of seven transmembrane helices embedded in the lipid membrane of ...