Blar i forfatter Det helsevitenskapelige fakultet "Fagerberg, Linn"

Viser treff 1-2 av 2

    • A single-cell type transcriptomics map of human tissues 

      Karlsson, Max; Cheng, Zhang; Mear, Lorén; Zhong, Wen; Digre, Andreas; Katona, Barbola; Sjöstedt, Evelina; Butler, Lynn; Odeberg, Jacob; Dusart, Philip James; Edfors, Fredrik; Oksvold, Per; von Feilitzen, Kalle; Zwahlen, Martin; Arif, Muhammad; Altay, Ozlem; Li, Xiangyu; Ozcan, Mehmet; Mardinoglu, Adil; Fagerberg, Linn; Mulder, Jan; Luo, Younglun; Ponten, Fredrik; Uhlén, Mathias; Lindskog, Cecilia (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-28)
      Advances in molecular profiling have opened up the possibility to map the expression of genes in cells, tissues, and organs in the human body. Here, we combined single-cell transcriptomics analysis with spatial antibodybased protein profiling to create a high-resolution single–cell type map of human tissues. An open access atlas has been launched to allow researchers to explore the expression of ...

    • Systematic development of sandwich immunoassays for the plasma secretome 

      Häussler, Ragna S.; Bendes, Annika; Iglesias, Maria Jesus; Sanchez-Rivera, Laura; Dodig‐Crnković, Tea; Byström, Sanna; Fredolini, Claudia; Birgersson, Elin; Dale, Matilda; Edfors, Fredrik; Fagerberg, Linn; Rockberg, Johan; Tegel, Hanna; Uhlén, Mathias; Qundos, Ulrika; Schwenk, Jochen M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-06)
      The plasma proteome offers a clinically useful window into human health. Recent advances from highly multiplexed assays now call for appropriate pipelines to validate individual candidates. Here, a workflow is developed to build dual binder sandwich immunoassays (SIA) and for proteins predicted to be secreted into plasma. Utilizing suspension bead arrays, ≈1800 unique antibody pairs are first screened ...