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dc.contributor.authorSmetkin, Alexey Anatolievich
dc.contributor.authorKuzkov, Vsevolod
dc.contributor.authorSuborov, Evgeny
dc.contributor.authorBjertnæs, Lars J.
dc.contributor.authorKirov, Mikhail
dc.date.accessioned2013-03-08T09:48:11Z
dc.date.available2013-03-08T09:48:11Z
dc.date.issued2012
dc.description.abstractIn acute respiratory distress syndrome (ARDS) the recruitment maneuver (RM) is used to reexpand atelectatic areas of the lungs aiming to improve arterial oxygenation. The goal of our paper was to evaluate the response to RM, as assessed by measurements of extravascular lung water index (EVLWI) in ARDS patients. Materials and Methods. Seventeen adult ARDS patients were enrolled into a prospective study. Patients received protective ventilation. The RM was performed by applying a continuous positive airway pressure of 40 cm H2O for 40sec. The efficacy of the RM was assessed 5 min later. Patients were identified as responders if PaO2/FiO2 increased by >20% above the baseline. EVLWI was assessed by transpulmonary thermodilution before the RM, and patients were divided into groups of low EVLWI (<10 mL/kg) and high EVLWI (≥10 mL/kg). EVLWI was increased in 12 patients. Following RM, PaO2/FiO2 increased by 33 (4–65) % in the patients with low EVLWI, whereas those in the high EVLWI group experienced a change by only −1((−13)–(+5)) % (P = 0.035). Conclusion. In ARDS, the response to a recruitment maneuver might be related to the severity of pulmonary edema. In patients with incresed EVLWI, the recruitment maneuver is less effective.en
dc.identifier.citationCritical Care Research and Practice (2012), Volume 2012 , Article ID 606528, 7 ppen
dc.identifier.cristinIDFRIDAID 972614
dc.identifier.doihttp://dx.doi.org/10.1155/2012/606528
dc.identifier.issn2090-1305
dc.identifier.urihttps://hdl.handle.net/10037/4927
dc.identifier.urnURN:NBN:no-uit_munin_4632
dc.language.isoengen
dc.publisherHindawi Publishing Corporationen
dc.rights.accessRightsopenAccess
dc.subjectVDP::Medical disciplines: 700::Clinical medical disciplines: 750::Lung diseases: 777en
dc.subjectVDP::Medisinske Fag: 700::Klinisk medisinske fag: 750::Lungesykdommer: 777en
dc.titleIncreased Extravascular Lung Water reduces the Efficacy of Alveolar Recruitment Maneuver in Acute Respiratory Distress Syndrome.en
dc.typeJournal articleen
dc.typeTidsskriftartikkelen
dc.typePeer revieweden


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