High expression of CD20+ lymphocytes in soft tissue sarcomas is a positive prognostic indicator

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https://hdl.handle.net/10037/5023
DOI
http://dx.doi.org/10.4161/onci.1.1.17825
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Date
2012
Type
Journal article
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Author
Sørbye, Sveinung Wergeland; Kilvær, Thomas Karsten; Valkov, Andrey Yurjevich; Dønnem, Tom; Smeland, Eivind; Al-Shibli, Khalid Ibrahim; Bremnes, Roy M.; Busund, Lill-Tove
Abstract
The immune status is important in cancer patients. Tissue microarrays from 249 patients with soft tissue sarcomas were constructed. Immunohistochemistry was used to evaluate the CD3+, CD4+, CD8+, CD20+ and CD45+ lymphocytes in tumors. High density of CD20+ lymphocytes is an independent positive prognostic indicator for these patients.
Citation
OncoImmunology 1(2012) nr. 1 s. 75-77
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