Blar i tittel Artikler, rapporter og annet (klinisk medisin)

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    • Ambulance helicopter contribution to search and rescue in North Norway 

      Glomseth, Ragnar; Gulbrandsen, Fritz I.; Fredriksen, Knut (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-13)
      Background: Search and rescue (SAR) operations constitute a significant proportion of Norwegian ambulance helicopter missions, and they may limit the service’s capacity for medical operations. We compared the relative contribution of the different helicopter resources using a common definition of SAR-operation in order to investigate how the SAR workload had changed over the last years. Methods: We ...

    • Ambulatory blood pressure as risk factor for long-term kidney function decline in the general population: a distributional regression approach 

      Eriksen, Bjørn Odvar; Fasiolo, Matteo; Mathisen, Ulla Dorte; Jenssen, Trond; Stefansson, Vidar Tor Nyborg; Melsom, Toralf (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-08-31)
      The results of randomized controlled trials are unclear about the long-term efect of blood pressure (BP) on kidney function assessed as the glomerular fltration rate (GFR) in persons without chronic kidney disease or diabetes. The limited duration of follow-up and use of imprecise methods for assessing BP and GFR are important reasons why this issue has not been settled. Since a long-term randomized ...

    • Ambulatory vocal acoustics, temporal dynamics, and serious mental illness 

      Cohen, Alex S.; Fedechko, Taylor L.; Schwartz, Elana K.; Le, Thanh P.; Foltz, Peter W.; Bernstein, Jared; Cheng, Jian; Holmlund, Terje Bektesevic; Elvevåg, Brita (Journal article; Tidsskriftartikkel; Peer reviewed, 2019)
      Acoustic analysis of vocal expression offers a potentially inexpensive, unobtrusive, and highly sensitive biobehavioral measure of serious mental illness (SMI)-related issues. Despite literature documenting its use for understanding SMI, prior studies have largely ignored that vocal expression is highly dynamic within individuals over time. We employed ambulatory vocal assessment from SMI outpatients ...

    • Amnioexchange for gastroschisis does not help, and may even harm 

      Bhide, Amarnath (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-24)
      This is a mini commentary on D Luton et al., pp. 1233–1241 in this issue. To view this article visit https://doi.org/10.1111/1471-0528.15804.

    • Amoxicillin did not Reduce Modic Change Oedema in Patients with Chronic Low Back pain - subgroup Analyses of a Randomised Trial (the AIM study) 

      Kristoffersen, Per Martin; Vetti, Nils; Grøvle, Lars; Brox, Jens Ivar; Bråten, Lars Christian Haugli; Grotle, Margreth; Haugen, Anne Julsrud; Rolfsen, Mads Peder; Froholdt, Anne; Skouen, Jan Sture; Lutro, Olav; Marchand, Gunn Hege; Anke, Audny Gabriele Wagner; Zwart, John Anker Henrik; Storheim, Kjersti; Assmus, Jörg; Espeland, Ansgar (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-12)
      <p><b> Study Design. </b> Exploratory subgroup analyses of a randomised trial (Antibiotics In Modic changes (AIM) study). <p><b> Objective. </b> To assess the effect of amoxicillin versus placebo in reducing Modic change (MC) oedema in patients with chronic low back pain (LBP). <p><b> Summary of Background Data. </b> The AIM study showed a small, clinically insignificant effect of ...

    • Anaemia and thrombocytopenia in patients with prostate cancer and bone metastases 

      Haukland, E; Nieder, Carsten; Pawinski, Adam; Dalhaug, Astrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)

    • Anal incontinence, urinary incontinence and sexual problems in primiparous women - a comparison between women with episiotomy only and women with episiotomy and obstetric anal sphincter injury 

      Stedenfeldt, Mona; Pirhonen, Jouko; Blix, Ellen; Wilsgaard, Tom; Vonen, Barthold; Øian, Pål (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Anal Sphincter Length as Determined by 3-Dimensional Endoanal Ultrasound and Anal Manometry: A Study in Healthy Nulliparous Women 

      Norderval, Stig; Pedersen, Torunn; Collinson, Rowan J. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-23)
      <i>Objectives</i> - The normal female external anal sphincter (EAS) is shorter anteriorly than laterally and posteriorly. Furthermore, the thickness of the very proximal part of the circular EAS is thinner than 50% of the lateral and posterior EAS thickness. The extent of these features is not fully explored. The aim of this prospective study was to assess the normal anal sphincter with 3‐dimensional ...

    • Analysing mHealth usage logs in RCTs: Explaining participants’ interactions with type 2 diabetes self-management tools 

      Bradway, Meghan; Pfuhl, Gerit; Joakimsen, Ragnar Martin; Ribu, Lis; Grøttland, Astrid; Årsand, Eirik (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-08-30)
      <p><i>Background</i>: The Introduction of mobile health (mHealth) devices to health intervention studies challenges us as researchers to adapt how we analyse the impact of these technologies. For interventions involving chronic illness self-management, we must consider changes in behaviour in addition to changes in health. Fortunately, these mHealth technologies can record participants’ interactions ...

    • Analysis of Antibiotic Exposure and Early-Onset Neonatal Sepsis in Europe, North America, and Australia 

      Giannoni, Eric; Dimopoulou, Varvara; Klingenberg, Claus Andreas; Navér, Lars; Nordberg, Viveka; Berardi, Alberto; El Helou, Salhab; Fusch, Gerhard; Bliss, Joseph M.; Lehnick, Dirk; Guerina, Nicholas; Seliga-Siwecka, Joanna; Maton, Pierre; Lagae, Donatienne; Mari, Judit; Janota, Jan; Agyeman, Philipp K A; Pfister, Riccardo; Latorre, Giuseppe; Maffei, Gianfranco; Laforgia, Nicola; Mózes, Eniko; Størdal, Ketil; Strunk, Tobias; Stocker, Martin (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-23)
      <p><b> IMPORTANCE</b> Appropriate use of antibiotics is life-saving in neonatal early-onset sepsis (EOS), but overuse of antibiotics is associated with antimicrobial resistance and long-term adverse outcomes. Large international studies quantifying early-life antibiotic exposure along with EOS incidence are needed to provide a basis for future interventions aimed at safely reducing neonatal ...

    • Analysis of methylation data with imputation with blocks (MethylBlocks) 

      Meng, Wei; Ray, Mithlesh Kumar; Fenton, Christopher Graham; Anderssen, Endre; Paulssen, Ruth H (Conference object; Konferansebidrag, 2022)
      <p><i>Background -</i> Analysis of methylation data is dependent on two inputs. The total number of reads at any given cytosine site (coverage), and how many of those cytosines are methylated (methylation). Both the large number of sites and low coverage can cause problems in the analysis of methylation data. Likewise finding DMR is computationally and statistically challenging. Here we present a ...

    • Analysis of the immune microenvironment in resected non-small cell lung cancer: The prognostic value of different T lymphocyte markers 

      Usó, Marta; Jantus-Lewintre, Eloísa; Bremnes, Roy M.; Calabuig, Silvia; Blasco, Ana; Pastor, Enrique; Borreda, Irene; Molina-Pinelo, Sonia; Paz-Ares, Luis; Guijarro, Ricardo; Martorell, Miguel; Forteza, Jerónimo; Camps, Carlos; Sirera, Rafael (Journal article; Tidsskriftartikkel; Peer reviewed, 2016)
      The prognosis of non-small cell lung cancer (NSCLC) remains poor and heterogeneous and new biomarkers are needed. As the immune system plays a pivotal role in cancer, the study of immune-related markers may provide valuable prognostic information of NSCLC. In 122 formalin-fixed, paraffin-embedded tumor tissue samples from early-stage NSCLC, tumor and tumor-near stromal areas were microdissected and ...

    • Antenatal breastmilk expression for women with diabetes in pregnancy - a feasibility study 

      Johnsen, Maren; Klingenberg, Claus; Brand, Meta; Revhaug, Arthur; Andreassen, Gunnbjørg (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-23)
      <p>Background: Mothers with diabetes are less likely to achieve successful breastfeeding. Antenatal breastmilk expression (ABE) may facilitate earlier breastfeeding, but feasibility of introducing ABE and its acceptance among Scandinavian women have previously not been investigated. <p>Methods: This observational trial was conducted between the 1 January 2019 and the 12 March 2020 in Tromsø, Norway. ...

    • Antenatal breastmilk expression for women with diabetes in pregnancy - a feasibility study 

      Johnsen, Maren; Klingenberg, Claus; Brand, Meta; Revhaug, Arthur; Andreassen, Gunnbjørg (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-23)
      <i>Background</i> - Mothers with diabetes are less likely to achieve successful breastfeeding. Antenatal breastmilk expression (ABE) may facilitate earlier breastfeeding, but feasibility of introducing ABE and its acceptance among Scandinavian women have previously not been investigated.<br><br> <i>Methods</i> - This observational trial was conducted between the 1 January 2019 and the 12 March ...

    • Anterior surgical treatment for cervical degenerative radiculopathy: a prediction model for non-success 

      Mjåset, Christer; Solberg, Tore; Zwart, John Anker Henrik; Småstuen, Milada Cvancarova; Kolstad, Frode; Grotle, Margreth (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-08)
      Purpose By using data from the Norwegian Registry for Spine Surgery, we wanted to develop and validate prediction models for non-success in patients operated with anterior surgical techniques for cervical degenerative radiculopathy (CDR).<p> <p>Methods This is a multicentre longitudinal study of 2022 patients undergoing CDR surgery and followed for 12 months to fnd prognostic models for non-success ...

    • Anti-apoptotic genes and non-coding RNAs are potential outcome predictors for ulcerative colitis 

      Meng, Wei; Johnsen, Kay-Martin; Fenton, Christopher Graham; Florholmen, Jon; Paulssen, Ruth H (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-05-18)
      Due to the lack of clinical, immunologic, genetic, and laboratory markers to predict remission in ulcerative colitis (UC) without relapse, there is no clear recommendation regarding withdrawal of therapy. Therefore, this study was to investigate if transcriptional analysis together with Cox survival analysis might be able to reveal molecular markers that are specific for remission duration and ...

    • Anti-type II collagen antibodies, anti-CCP, IgA RF and IgM RF are associated with joint damage, assessed eight years after onset of juvenile idiopathic arthritis (JIA) 

      Berntson, Lillemor; Nordal, Ellen Berit; Fasth, Anders; Aalto, Kristiina; Herlin, T; Nielsen, Susan; Rygg, Marite; Zak, M; Ronnelid, J (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Antibiotic treatment for appendicitis in Norway and Sweden: a nationwide survey on treatment practices 

      Gran, M.V.; Kjønås, Didrik; Gunnarsson, U.; Strigård, K.; Revhaug, Arthur; Aahlin, Eirik Kjus (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-06-15)
      Background: Appendicitis is one of the most common causes of acute abdomen. Uncomplicated appendicitis is as an infamed appendix without perforation, gangrene or abscess formation. Recent trials show that one can safely treat uncomplicated appendicitis with antibiotics, given patient approval and appropriate follow-up. A recent study has also indicated no diference between antibiotic treatment ...

    • Antibiotic treatment In patients with chronic low back pain and Modic changes (the AIM study): study protocol for a randomised controlled trial. 

      Storheim, Kjersti; Espeland, Ansgar; Grøvle, Lars; Skouen, Jan Sture; Assmus, Jörg; Anke, Audny; Froholdt, Anne; Pedersen, Linda Margareth; Haugen, A. J.; Fors, Terese; Lutro, Olav; Marchand, Gunn Hege; Kadar, Thomas; Vetti, Nils; Randen, Solfrid; Nygaard, Øystein Petter; Brox, Jens Ivar; Grotle, Margreth; Zwart, John-Anker (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-12-15)
      Background: <br>A previous randomised controlled trial (RCT) of patients with chronic low back pain (LBP) and vertebral bone marrow (Modic) changes (MCs) on magnetic resonance imaging (MRI), reported that a 3-month, high-dose course of antibiotics had a better effect than placebo at 12 months’ follow-up. The present study examines the effects of antibiotic treatment in chronic LBP patients with ...

    • Antibiotic Use in Term and Near-Term Newborns 

      Mundal, Håkon S.; Rønnestad, Arild Erland; Klingenberg, Claus Andreas; Stensvold, Hans Jørgen; Størdal, Ketil (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-01)
      OBJECTIVES - We aimed to study whether national and local antibiotic stewardship projects have reduced the antibiotic use in newborns and to monitor potential changes in adverse outcomes.<p> <p>METHODS - In a nationwide, population-based study from Norway, we included all hospital live births from 34 weeks' gestation (n = 282 046) during 2015 to 2019. The primary outcome was the proportion of ...