Blar i tittel Artikler, rapporter og annet (klinisk medisin)

Viser treff 1394-1413 av 1796

    • Randomised comparison of provisional side branch stenting versus a two-stent strategy for treatment of true coronary bifurcation lesions involving a large side branch: the Nordic-Baltic Bifurcation Study IV 

      Kumsars, Indulis; Holm, Niels Ramsing; Niemelä, Matti; Erglis, Andrejs; Kervinen, Kari; Kervinen, Evald Høj; Maeng, Michael; Dombrovskis, Andis; Abraitis, Vytautas; Kibarskis, Aleksandras; Trovik, Thor; Latkovskis, Gustavs; Sondore, Dace; Narbute, Inga; Juhl Terkelsen, Christian; Eskola, Markko; Romppanen, Hannu; Laine, Mika; Jensen, Lisette Okkels; Pietila, Mikko; Gunnes, Pål; Hebsgaard, Lasse; Frobert, Ole; Calais, Fredrik; Hartikainen, Juha; Aarøe, Jens; Ravkilde, Jan; Engstrøm, Thomas; Steigen, Terje K.; Thuesen, Leif; Lassen, Jens F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-19)
      <i>Background</i> - It is still uncertain whether coronary bifurcations with lesions involving a large side branch (SB) should be treated by stenting the main vessel and provisional stenting of the SB (simple) or by routine two-stent techniques (complex). We aimed to compare clinical outcome after treatment of lesions in large bifurcations by simple or complex stent implantation.<p> <p><i>Methods</i> ...

    • A randomised placebo-controlled trial examining the effect on hand supination after the addition of a suprascapular nerve block to infraclavicular brachial plexus blockade 

      Flohr-Madsen, Sandra; Ytrebø, Lars Marius; Valen, Katrin; Wilsgaard, Tom; Klaastad, Øivind (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-07-11)
      Some surgeons believe that infraclavicular brachial plexus blocks tends to result in supination of the hand/forearm, which may make surgical access to the dorsum of the hand more difficult. We hypothesised that this supination may be reduced by the addition of a suprascapular nerve block. In a double‐blind, randomised, placebo‐controlled study, our primary outcome measure was the amount of supination ...

    • Randomized phase II trial comparing twice daily hyperfractionated with once daily hypofractionated thoracic radiotherapy in limited disease small cell lung cancer 

      Grønberg, Bjørn Henning; Halvorsen, Tarje Onsøien; Fløtten, Øystein; Brustugun, Odd Terje; Brunsvig, Paal Fr.; Aasebø, Ulf; Bremnes, Roy M.; Tollåli, Terje; Hornslien, Kjersti; Aksnessæther, Bjørg Y.; Liaaen, Erik Dyb; Sundstrøm, Stein Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10-23)
      <br>BACKGROUND: <br> Concurrent chemotherapy and thoracic radiotherapy (TRT) is recommended for limited disease small cell lung cancer (LD SCLC). Twice daily TRT is well documented, but not universally implemented - probably mainly due to inconvenience and concerns about toxicity. A schedule of three-week hypofractionated TRT is a commonly used alternative. This is the first randomized trial ...

    • Randomized trial of a novel game-based appointment system for a university hospital venereology unit: Study protocol 

      Gabarron, Elia; Fernandez-Luque, Luis; Serrano, Artur; Wynn, Rolf; Schopf, Thomas Roger Griesbeck (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-08)
      Background: Chlamydia is the most common reportable sexually transmitted disease (STD) in Norway, and its incidence in the two northernmost counties has been disclosed to be nearly the double of the Norwegian average. The latest publicly available rates showed that 85.6% of the new cases were diagnosed in people under 29 years old. The information and communication technologies are among the most ...

    • Randomized trial of a novel game-based appointment system for a university hospital venereology unit: Study protocol 

      Gabarron, Elia; Serrano, Artur; Fernandez Luque, Luis; Wynn, Rolf; Schopf, Thomas Roger Griesbeck (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-04-08)
      <p>Background: Chlamydia is the most common reportable sexually transmitted disease (STD) in Norway, and its incidence in the two northernmost counties has been disclosed to be nearly the double of the Norwegian average. The latest publicly available rates showed that 85.6% of the new cases were diagnosed in people under 29 years old. The information and communication technologies are among the ...

    • Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction 

      Broch, Kaspar; Anstensrud, Anne Kristine; Woxholt, Sindre; Sharma, Kapil Kishore; Tøllefsen, Ingvild Maria; Bendz, Bjørn; Aakhus, Svend; Ueland, Thor; Amundsen, Brage H.; Damås, Jan Kristian; Berg, Erlend; Bjørkelund, Elisabeth; Bendz, Christina; Hopp, Einar; Kleveland, Ola; Stensæth, Knut Haakon; Opdahl, Anders; Kløw, Nils-Einar; Seljeflot, Ingebjørg; Andersen, Geir Øystein; Wiseth, Rune; Aukrust, Pål; Gullestad, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-12)
      <p><i>Background - </i>Prompt myocardial revascularization with percutaneous coronary intervention (PCI) reduces infarct size and improves outcomes in patients with ST-segment elevation myocardial infarction (STEMI). However, as much as 50% of the loss of viable myocardium may be attributed to the reperfusion injury and the associated inflammatory response. <p><i>Objectives - </i>This study sought ...

    • A randomized trial of telemedicine efficacy and safety for nonacute headaches 

      Müller, Kai Ivar; Alstadhaug, Karl Bjørnar; Bekkelund, Svein Ivar (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-07-11)
      <p><i>Objective</i>: To evaluate long-term treatment efficacy and safety of one-time telemedicine consultations for nonacute headaches.</p> <p><i>Methods</i>: We randomized, allocated, and consulted nonacute headache patients via telemedicine (n = 200) or in a traditional manner (n = 202) in a noninferiority trial. Efficacy endpoints, assessed by questionnaires at 3 and 12 months, included change ...

    • A rapid chemokine response of macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta and the regulated on activation, normal T expressed and secreted chemokine is associated with a sustained virological response in the treatment of chronic hepatitis C 

      Florholmen, Jon; Kristiansen, Magnhild Gangsøy; Steigen, sonja eriksson; Sørbye, Sveinung Wergeland; Paulssen, Eyvind Jakob; Kvamme, J.M.; Zbigniew, Konopski; Gutteberg, tore jarl; Goll, Rasmus (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The role of chemokines in chronic hepatitis C virus (HCV) infection is not fully understood. The present study aimed to characterize the baseline serum concentrations and the initial β-chemokine response to treatment with interferon-α and ribavirin with respect to the final clinical outcome of virological response to treatment. Serum concentrations of alanine aminotransferase (ALT) and of the CC ...

    • Rapid extrication of entrapped victims in motor vehicle wreckage using a Norwegian chain method - cross-sectional and feasibility study 

      Fattah, Sabina; Johnsen, Anne Siri; Andersen, Jan Einar; Vigerust, Trond; Olsen, Terje; Rehn, Marius (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)

    • Rapid identification of pathogens, antibiotic resistance genes and plasmids in blood cultures by nanopore sequencing 

      Taxt, Arne Michael; Avershina, Ekaterina; Frye, Stephan Alfons; Naseer, Mohammed Umaer; Ahmad, Rafi (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-06)
      Bloodstream infections (BSI) and sepsis are major causes of morbidity and mortality worldwide. Blood culture-based diagnostics usually requires 1–2 days for identification of bacterial agent and an additional 2–3 days for phenotypic determination of antibiotic susceptibility pattern. With the escalating burden of antimicrobial resistance (AMR) rapid diagnostics becomes increasingly important to ...

    • A rapid, sensitive, and specific assay to measure TF activity based on chromogenic determination of thrombin generation 

      Østerud, Bjarne; Latysheva, Nadezhda; Schoergenhofer, Christian; Jilma, Bernd; Hansen, John-Bjarne; Snir, Omri (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-11-25)
      Background - Most tissue factor (TF) activity assays are based on measurement of factor X (FX) activation by TF in the presence of factor VII (FVII)/FVIIa. This requires long incubation, which may result in TF-independent activity of FX and inaccurate measurement of TF activity.<p> <p>Aim - To develop a sensitive and specific TF activity assay, which does not register a non-specific TF activity, ...

    • Rapport fra 25. juni-utvalget: Evaluering av PST og politiet 

      Jansen, Pia Therese; Ravndal, Jacob Aasland; Skoglund, Gisle; Eriksen, Christoffer Conrad; Hoven, Siren; Løberg, Anders; Rolfheim-Bye, Christina Lill (Research report; Forskningsrapport, 2023)

    • Rapport omsvangerskapsavbrot 2022 

      Akerkar, Rupali Rajendra; Askeland, Olaug Margrete; Halvorsen, Guri Sundgot; Heiberg-Andersen, Rannveig; Hornæs, Mona Tornensis; Juliusson, Pétur Benedikt; Berg, Amund (Research report; Forskningsrapport, 2023)
      Det føreligg statistikk over talet på begjæringar, tal på innvilga begjæringar i nemnd og tal på utførte svangerskapsavbrot i Noreg sidan 1979. Statistisk sentralbyrå hadde ansvaret for abortstatistikken frå 1979 til og med 2005. Frå og med 2006 har Folkehelseinstituttet vore ansvarleg for statistikken, og frå og med 2008 ansvarleg for databehandlinga av Register over svangerskapsavbrudd (Abo ...

    • Rat liver sinusoidal endothelial cells (LSECs) express functional low density lipoprotein receptor-related protein-1 (LRP-1) 

      Øie, Cristina Ionica; Appa, Rupa Shree; Hilden, Ida; Petersen, Helle Heibroch; Gruhler, Albrecht; Smedsrød, Bård; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The low density lipoprotein receptor-related protein-1 (LRP-1) is a large, multifunctional endocytic receptor from the LDL receptor family, highly expressed in liver parenchymal cells (PCs), neurons, activated astrocytes, and fibroblasts. The aim of the study was to investigate if liver sinusoidal endothelial cells (LSECs), highly specialized scavenger cells, express LRP-1. To address this question, ...

    • The rates of lumbar spinal stenosis surgery in Norwegian public hospitals: a threefold increase from 1999 to 2013 

      Grøvle, Lars; Fjeld, Olaf Randall; Haugen, Anne Julsrud; Helgeland, Jon; Småstuen, Milada Cvancarova; Solberg, Tore; Zwart, John-Anker; Grotle, Margreth (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-17)
      <p><i>Study Design</i>: Retrospective administrative database study.</p> <p><i>Objective</i>: To assess temporal and regional trends, and length of hospital stay, in lumbar spinal stenosis (LSS) surgery in Norwegian public hospitals from 1999 to 2013.</p> <p><i>Summary of Background Data</i>: Studies from several countries have reported increasing rates of LSS surgery over the last decades. ...

    • Rationale and plan for vitamin D food fortification: A review and guidance paper 

      Pilz, Stefan; März, Winfried; Cashman, Kevin D; Kiely, Mairead; Whiting, Susan J; Holick, Michael F.; Grant, William B; Pludowski, Pawel; Hiligsmann, Mickaël; Trummer, Christian; Schwetz, Verena; Lerchbaum, Elisabeth; Pandis, Marlene; Tomaschitz, Andreas; Grübler, Martin; Gaksch, Martin; Verheyen, Nicolas; Hollis, Bruce W; Rejnmark, Lars; Karras, Spyridon N.; Hahn, Andreas; Bischoff-Ferrari, Heike Annette; Reichrath, Jörg; Jorde, Rolf; Elmadfa, Ibrahim; Vieth, Reinhold; Scragg, Robert; Calvo, Mona S; Van Schoor, Natasja M; Bouillon, Roger; Lips, Paul; Itkonen, Suvi T; Martineau, Adrian R; Lamberg-Allardt, Christel; Zittermann, Armin (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-17)
      Vitamin D deficiency can lead to musculoskeletal diseases such as rickets and osteomalacia, but vitamin D supplementation may also prevent extraskeletal diseases such as respiratory tract infections, asthma exacerbations, pregnancy complications and premature deaths. Vitamin D has a unique metabolism as it is mainly obtained through synthesis in the skin under the influence of sunlight (i.e., ...

    • Re-irradiation in clinical practice: Results of an international patterns of care survey within the framework of the ESTRO-EORTC E2-RADIatE platform 

      Willmann, Jonas; Appelt, L.; Balermpas, Panagiotis; Baumert, G.; de Ruysscher, Dirk; Hoyer, Morten; Hurkmans, Coen; Kaidar-Person, Orit; Meattini, Icro; Niyazi, Maximilian; Poortmans, Philip; Reynaert, Nick; Tandini-Lang, Stephanie; van der Linden, Yvette; Nieder, Carsten; Andratschke, Nicolaus (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-06)
      Background: Re-irradiation is an increasingly utilized treatment for recurrent, metastatic or new malignancies after previous radiotherapy. It is unclear how re-irradiation is applied in clinical practice. We aimed to investigate the patterns of care of re-irradiation internationally.<p> <p>Material/Methods: A cross-sectional survey conducted between March and September 2022. The survey was structured ...

    • Real-world comparison of the effects of etanercept and adalimumab on well-being in non-systemic juvenile idiopathic arthritis: a propensity score matched cohort study 

      van Straalen, Joeri W.; de Roock, Sytze; Giancane, Gabriella; Consolaro, Alessandro; Rygg, Marite; Nordal, Ellen Berit; Rubio-Pérez, Nadina; Jelusic, Marija; De Inocencio, Jaime; Vojinovic, Jelena; Wulffraat, Nico M.; Bruijning-Verhagen, Patricia C. J.; Ruperto, Nicolino; Swart, Joost F. (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-14)
      Background: Etanercept (ETN) and adalimumab (ADA) are considered equally efective biologicals in the treat‑ ment of arthritis in juvenile idiopathic arthritis (JIA) but no studies have compared their impact on patient-reported well-being. The objective of this study was to determine whether ETN and ADA have a diferential efect on patientreported well-being in non-systemic JIA using real-world ...

    • Recent advances in the roles of exosomal microRNAs in neuroblastoma 

      Bhavsar, Swapnil (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-10)
      Exosomal miRNAs (exo-miRs), universally found in biofluids, tissues, and/or conditioned medium of the cell cultures play a significant role in cell - cell communication, thus driving cancer progression and metastasis. Very few studies have explored the role of exo-miRs in the progression of children’s cancer - neuroblastoma. In this mini review, I briefly summarize the existing literature on the ...

    • The recent history of the clinical case report: A narrative review 

      Nissen, Trygve; Wynn, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)
      Clinical case reporting in the form of case reports and case series reports has always been an integral part of medical literature. From the late 1970s the genre appeared to fall from grace and was marginalized in many medical journals. There was controversy as to its value as a research method. From the late 1990s and onwards, there has been an increased demand for and publication of case reports ...