Sattler, Bernhard; Kranz, Mathias; Wenzel, Barbara; Jain, Nalin T.; Moldovan, Rareş-Petru; Toussaint, Magali; Deuther-Conrad, Winnie; Ludwig, Friedrich-Alexander; Teodoro, Rodrigo; Sattler, Tatjana; Sadeghzadeh, Masoud; Sabri, Osama; Brust, Peter (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-26)
Overexpression of monocarboxylate transporters (MCTs) has been shown for a variety of human cancers (e.g., colon, brain, breast, and kidney) and inhibition resulted in intracellular lactate accumulation, acidosis, and cell death. Thus, MCTs are promising targets to investigate tumor cancer metabolism with positron emission tomography (PET). Here, the organ doses (ODs) and the effective dose (ED) of ...