Park, Christopher Y.; Wong, Aaron K.; Greene, Casey S.; Rowland, Jessica; Guan, Yuanfang; Bongo, Lars Ailo; Burdine, Rebecca D.; Troyanskaya, Olga (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
A key challenge in genetics is identifying the functional roles of genes in pathways. Numerous functional genomics
techniques (e.g. machine learning) that predict protein function have been developed to address this question. These
methods generally build from existing annotations of genes to pathways and thus are often unable to identify additional
genes participating in processes that are not ...