Dønnem, Tom; Hu, Jiangting; Ferguson, M.; Adighibe, Omanma; Snell, Cameron; Harris, Adrian L.; Gatter, Kevin C; Pezzella, F (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)
Angiogenesis has been regarded as essential for tumor growth and progression.
Studies of many human tumors, however, suggest that their microcirculation
may be provided by nonsprouting vessels and that a variety of tumors can grow
and metastasize without angiogenesis. Vessel co-option, where tumor cells
migrate along the preexisting vessels of the host organ, is regarded as an alternative
tumor ...