Browsing by Author "Killie, Mette Kjær"
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Anti-human platelet antigen-1α immunoglobulin G preparation intended to prevent fetal and neonatal alloimmune thrombocytopenia
Weng, Ying-Jan; Husebekk, Anne; Skogen, Bjørn Ragnar; Killie, Mette Kjær; Lin, Liang-Tzung; Burnouf, Thierry (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-09-14)Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a severe disease that is caused by maternal alloantibodies generated during pregnancy or at delivery as a result of incompatibility between maternal and fetal human platelet antigens (HPAs) inherited from the father. Antibody-mediated immune suppression using anti-HPA-1a immunoglobulins is thought to be able to prevent FNAIT caused by ... -
The development of severe Neonatal Alloimmune Thrombocytopenia due to Anti-HPA-1a Antibodies is correlated to maternal ABO genotypes
Ahlen, Maria Therese; Husebekk, Anne; Killie, Mette Kjær; Kjeldsen-Kragh, Jens; Olsson, Martin L.; Skogen, Bjørn Ragnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2012)Background. Maternal alloantibodies against HPA-1a can cross placenta, opsonize foetal platelets, and induce neonatal alloimmune thrombocytopenia (NAIT). In a study of 100, 448 pregnant women in Norway during 1995–2004, 10.6% of HPA-1a negative women had detectable anti-HPA-1a antibodies. Design and Methods. A possible correlation between the maternal ABO blood group phenotype, or underlying genotype, ... -
In HPA 1a-immunized women the decrease in anti-HPA 1a antibody level during pregnancy is not associated with anti-idiotypic antibodies
Kjeldsen-Kragh, J; Killie, Mette Kjær; Kim, Michael; Husebekk, Anne; Freedman, J; Semple, John W (Journal article; Tidsskriftartikkel, 2009) -
A prospective study of maternal anti-HPA1a antibody level as a potential predictor for alloimmune thrombocytopenia in the newborn
Husebekk, Anne; Killie, Mette Kjær; Kjeldsen-Kragh, Jens; Skogen, Bjørn Ragnar (Journal article; Tidsskriftartikkel; Peer reviewed, 2008)