Blar i forfatter "Larsen, Anette Uhlving"
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The effect of dosing regimen on outcomes of vitamin D supplementation trials. A study of current literature
Larsen, Anette Uhlving (Master thesis; Mastergradsoppgave, 2019-06-02)Results from observational studies have indicated associations between vitamin D and extra-skeletal outcomes, including respiratory tract infections (RTI) and all-cause mortality. However, available trial-data have shown inconsistent results. The main objective of this thesis was to investigate whether a beneficial effect of daily supplementation of vitamin D on RTI and all-cause mortality could ... -
The effect of high-dose vitamin D3 supplementation on bone mineral density in subjects with prediabetes
Larsen, Anette Uhlving; Grimnes, Guri; Jorde, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-09-18)<p><i>Summary</i> The rationale of this study was to determine the effect of high-dose vitamin D3 supplementation on bone mineral density (BMD). Prediabetic males given vitamin D had significantly less reduction in BMD at the femoral neck compared to the controls. The clinical implications of our findings require further investigation.</p> <p><i>Introduction</i> Type 2 diabetes mellitus is ... -
The effect of high-dose vitamin D3 supplementation on bone mineral density in subjects with prediabetes
Larsen, Anette Uhlving; Grimnes, G.; Jorde, R. (Master thesis; Mastergradsoppgave, 2019-10-30)Purpose: Type 2 diabetes mellitus is associated with increased fracture risk and recent studies show crosstalk between bone and glucose metabolism. Few studies have investigated the effect of vitamin D supplementation on bone without additional calcium. In the present study, we aimed to determine whether a high dose of vitamin D3 could improve bone mass density (BMD) in prediabetic subjects. Methods: ... -
No improvement of sleep from vitamin D supplementation: insights from a randomized controlled trial
Larsen, Anette Uhlving; Hopstock, Laila Arnesdatter; Jorde, Rolf; Grimnes, Guri (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-10-19)<i><p>Background</i> Vitamin D has been linked to sleep health in observational studies. Data from randomized controlled trials (RCTs) with vitamin D is scarce. <i><p>Methods</i> This study presents the results of a secondary analysis of 189 vitamin D insufficient participants (47.1% women) in a previously performed RCT, of which 92 were randomized to vitamin D (100,000 IU (2500 μg) as a ... -
Vitamin D: Relations with Sleep and Bone Mineral Density. Insights from the Tromsø Study and randomized controlled trials
Larsen, Anette Uhlving (Doctoral thesis; Doktorgradsavhandling, 2022-06-10)In this thesis, the relationship between vitamin D and health-related outcomes has been investigated. More than 21,000 individuals participated in the Tromsø Study 2015-16. The participants donated blood samples and filled in questionnaires regarding their health status, including questions about their sleep health. Using these data, the association between vitamin D and sleep duration, daytime ...