Horvei, Kjersti Daae; Pedersen, Hege Lynum; Fismen, Silje; Thiyagarajan, Dhivya; Schneider, Andrea; Rekvig, Ole Petter; Winkler, Thomas; Seredkina, Natalya (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-30)
FcγRIIB<sup>-/-</sup>yaa mice develop severe lupus glomerulonephritis due to lack of an inhibitory immune cell receptor combined with a Y-chromosome linked autoimmune accelerator mutation. In the present study, we have investigated nephritis development and progression in FcγRIIB<sup>-/-</sup>yaa mice to find shared features with NZB/NZW F1 lupus prone mice and human disease. We sacrificed 25 male ...