Browsing by Author "Zhou, Humin"
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B4GALT family mediates the multidrug resistance of human leukemia cells by regulating the hedgehog pathway and the expression of p-glycoprotein and multidrug resistance-associated protein 1
Zhou, Humin; Ma, Hongye; Wei, Wei; Ji, Donghua; Song, Xiaobo; Sun, Jinglu; Zhang, Jianing; Jia, Li (Journal article; Tidsskriftartikkel; Peer reviewed, 2013)b-1, 4-Galactosyltransferase gene (B4GALT) family consists of seven members, which encode corresponding enzymes known as type II membrane-bound glycoproteins. These enzymes catalyze the biosynthesis of different glycoconjugates and saccharide structures, and have been recognized to be involved in various diseases. In this study, we sought to determine the expressional profiles of B4GALT family ... -
MiR-493-5p attenuates the invasiveness and tumorigenicity in human breast cancer by targeting FUT4
Zhao, Lifen; Feng, Xiaobin; Song, Xiaobo; Zhou, Humin; Zhao, Yongfu; Cheng, Lei; Jia, Li (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-06-16)Breast cancer is a leading cause of cancer-related mortality among women. Altered fucosylation was found to be closely associated with tumorigenesis and metastasis of breast cancer. MicroRNAs (miRNAs) are important regulators of cell proliferation and metastasis, and aberrant miRNA expression has been observed in breast cancer. The present study aimed to evaluate the level of fucosyltransferase IV ...