Organizations often experience problems and challenges due to the development of rigid bureaucratic rules and procedures, which may represent obstacles to creativity and innovation. In a global knowledge economy, innovation is an important competitive parameter. Consequently, anything that may stimulate innovation in an organization’s creative energy fields is valuable. This paper addresses one ...

I denne artikkelen undersøker jeg vekslinga mellom VO- og OV-ordstilling i nordsamisk talemål. Jeg har gjort søk i LIA Sápmi – Sámegiela hállangiellakorpus. Resultatene mine viser ikke uventet at VO overordnet sett er det mest frekvente mønstret. Men i materialet mitt finner jeg også mange tilfeller av SAuxOV-ordstilling, spesielt i setninger med sammensatte verbformer hvor hovedverbet er i ...

Aims: Limb-girdle muscular dystrophy R9 (LGMDR9) is an autosomal recessive disorder caused by mutations in the fukutin-related protein gene (FKRP), encoding a glycosyltransferase involved in α-dystroglycan modification. Muscle atrophy, a significant feature of LGMDR9, occurs by a change in the normal balance between protein synthesis and protein degradation. The ubiquitin–proteasome system (UPS) ...

Platinum has been inserted into corroles for the first time and three oxidized Pt^IV(corrole^2-)ArAr0 complexes have been structurally characterized. The Soret maxima of these complexes exhibit an unusually strong dependence on the meso-aryl substituents on the corrole, indicating aryl - corrole^2- charge transfer character in these transitions.

Background: Early-stage non-small cell lung cancer (NSCLC) patients have a high risk of disease relapse despite curatively intended surgical resection, and the detection of tumour cells in the bone marrow could be one method of determining the presence of the disseminated disease in its early stages.<p> <p>Methods: Bone marrow aspirates were collected from 296 patients at the time of surgery, and ...

The warming and subsequent degradation of mountain permafrost within alpine areas represent an important process influencing the stability of steep slopes and rock faces. The unstable and monitored slopes of Mannen (Møre and Romsdal county, southern Norway) and Gámanjunni-3 (Troms and Finnmark county, northern Norway) were classified as high-risk sites by the Norwegian Geological Survey (NGU). ...

Background: The palliative role of chemoradiation in the treatment of patients with locally advanced, inoperable non-small-cell lung cancer stage III and negative prognostic factors remains unresolved.<p> <p>Methods: Patients not eligible for curative radiotherapy were randomised to receive either chemoradiation or chemotherapy alone. Four courses of intravenous carboplatin on day 1 and oral ...

Climate warming in the Arctic has resulted in widespread changes in the physical oceanographic characteristics of the Arctic Ocean. One particularly visible change is the loss of sea ice both within the Arctic Ocean and in the surrounding shelf seas. Compared to the other shelf seas, the Barents Sea has experienced the largest declines in sea ice extent, with much of this loss occurring during winter. ...

Parenting an adolescent with severe emotional difficulties is challenging, and research shows that when parents do not receive adequate support it can have adverse consequences for the parents, the adolescents, and their siblings. Dialectical behavioral therapy for adolescents (DBT-A) is a treatment method that has an increased focus on parental support, and by including parents in treatment DBT-A ...

Abstract: Introduction: Early acute antibody-mediated rejection (ABMR) occurs more frequently in ABO-incompatible (ABOi) than in ABO-compatible (ABOc) kidney transplantation. This could lead to increased inflammation/scarring in the ABOi grafts. Protocol biopsy data in ABOi kidney recipients are scarce.<p> <p>Methods: A single-center retrospective matched cohort study was conducted. Eighty ...