Proof-of-work based cryptocurrencies, like Bitcoin, have a fee market where transactions are included in the blockchain according to a first-price auction for block space. Many attempts have been made to adjust and predict the fee volatility, but even well-formed transactions sometimes experience delays and evictions unless an enormous fee is paid. % In this paper, we present a novel ...

Human ATG8 family proteins (ATG8s) are active in all steps of the macroautophagy pathway, and their lipidation is essential for autophagosome formation. Lipidated ATG8s anchored to the outer surface of the phagophore serve as scaffolds for binding of other core autophagy proteins and various effector proteins involved in trafficking or fusion events, whereas those at the inner surface are needed for ...

The article studies the effects of the emergence of cyberspace, or digitization, on civil society, and develops an analytical framework to that effect. It is distinguished between four types of civil societies: apolitical, political, transnational, and uncivic. Each type of civil society is considered separately vis-à-vis cyberspace developments in order to understand what kind of civil society is ...

A structured technology framework to address navigation considerations, including collision avoidance, of autonomous ships is the focus of this study. That consists of adequate maritime technologies to achieve the required level of navigation integrity in ocean autonomy. Since decision-making facilities in future autonomous vessels can play an important role under ocean autonomy, these technologies ...

This paper investigates manner variation of Israeli Hebrew rhotics with respect to two factors: prosodic position and speaker gender. An acoustic experimental study shows that although the Hebrew rhotic phoneme tends to be a dorsal approximant, it is significantly more likely to undergo fortition in onset position. This fortition is a result of target overshoot, the rhotic subsequently being produced ...

Growing epidemiologic evidence supports chronic inflammation as a mechanism of ovarian carcinogenesis. An association between a circulating marker of inflammation, C-reactive protein (CRP), and ovarian cancer risk has been consistently observed, yet, potential heterogeneity of this association by tumor and patient characteristics has not been adequately explored. In this study, we pooled data from ...

Large fields of view (FOVs) in total internal reflection fluorescence microscopy (TIRFM) via waveguides have been shown to be highly beneficial for single molecule localisation microscopy on fixed cells [1,2] and have also been demonstrated for short‐term live‐imaging of robust cell types [3‐5], but not yet for delicate primary neurons nor over extended periods of time. Here, we present a waveguide‐based ...

Let Gr(d, n) be the Grassmannian of <i>d</i>-dimensional linear subspaces of an <i>n</i>-dimensional vector space <i>V</i>. A submanifold <i>X</i> ⊂ Gr(<i>d, n</i>) gives rise to a differential system Σ(X) that governs <i>d</i>-dimensional submanifolds of <i>V</i> whose Gaussian image is contained in <i>X</i>. We investigate a special case of this construction where <i>X</i> is a six-fold in Gr(4, ...

Kundt waves belong to the class of spacetimes which are not distinguished by their scalar curvature invariants. We address the equivalence problem for the metrics in this class via scalar differential invariants with respect to the equivalence pseudo-group of the problem. We compute and finitely represent the algebra of those on the generic stratum and also specify the behavior for vacuum Kundt ...

The promotion of tourism has been considered to be a key strategy in reducing people's dependence on marine resources and for creating alternative livelihoods for the communities living in Marine Protected Areas (MPAs). This paper studies the determinants for the decision of participation in tourism-related activities and examines whether tourism could be regarded as an alternative livelihood for ...