Now showing items 23181-23200 of 37088

    • Area and volume of mid-latitude glacier-like forms on Mars 

      Brough, Stephen; Hubbard, Bryn; Hubbard, Alun Lloyd (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-04)
      Although a substantial ice cover has been identified within the mid-latitudes of Mars, there is uncertainty regarding the formation, current and former volume, and dynamic evolution of these ice masses. Here, we present the first comprehensive ice volume estimate of martian glacier-like forms (GLFs) from systematic population scale mapping and volumetric analysis. The outlines of 1243 GLFs were ...
    • Could green artificial light reduce bycatch during Barents Sea Deep-water shrimp trawling? 

      Larsen, Roger B.; Herrmann, Bent; Sistiaga, Manu Berrondo; Brčić, Jure; Brinkhof, Jesse; Tatone, Ivan (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-31)
      The Nordmøre grid is widely used in shrimp trawls to reduce the bycatch of fish species. However, small-sized fish species and juveniles still pass through the grid and enter the codend, along with the targeted shrimp. This bycatch of small fish has a negative impact on the ecosystem due to increased fish mortality, and leads to additional sorting work onboard. Some small-sized fish that enter the ...
    • Holocene development of subarctic permafrost peatlands in Finnmark, northern Norway 

      Kjellman, Sofia E.; Axelsson, Pia E.; Etzelmüller, Bernd; Westermann, Sebastian; Sannel, A. Britta K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-01)
      Subarctic permafrost peatlands are important soil organic carbon pools, and improved knowledge about peat properties and peatland sensitivity to past climate change is essential when predicting future response to a warmer climate and associated feedback mechanisms. In this study, Holocene peatland development and permafrost dynamics of four subarctic peat plateaus in Finnmark, northern Norway have ...
    • Dual-specificity MAP kinase phosphatases in health and disease 

      Seternes, Ole Morten; Kidger, Andrew M; Keyse, Stephen M (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-08)
      It is well established that a family of dual-specificity MAP kinase phosphatases (MKPs) play key roles in the regulated dephosphorylation and inactivation of MAP kinase isoforms in mammalian cells and tissues. MKPs provide a mechanism of spatiotemporal feedback control of these key signalling pathways, but can also mediate crosstalk between distinct MAP kinase cascades and facilitate interactions ...
    • Novel in situ gel-forming solid dosage form (gfSDF) prepared by the simple syringe-based moulding: A screening study 

      Falavigna, Margherita; Skalko-Basnet, Natasa; Cavallari, Cristina; Pini, Andrea; Luppi, Barbara; Di Cagno, Massimiliano Pio (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-05-05)
      The aim of this study was to prepare and optimize a novel type of in situ gel-forming solid dosage form (gfSDF) to be used in the treatment of mucosal/skin ulcerations. For this purpose, a simple but reliable syringe-based hot melt/moulding method was employed. Chloramphenicol (antibiotic) and ibuprofen (anti-inflammatory) were chosen as model active pharmaceutical ingredients (APIs) to be loaded ...
    • Interleukin-6 receptor inhibition with tocilizumab induces a selective and substantial increase in plasma IP-10 and MIP-1β in non-ST-elevation myocardial infarction 

      Kleveland, Ola; Ueland, Thor; Kunszt, Gabor; Bratlie, Marte; Yndestad, Arne; Broch, Kaspar; Holte, Espen; Ryan, Liv; Amundsen, Brage H.; Bendz, Bjørn; Aakhus, Svend; Espevik, Terje; Halvorsen, Bente; Mollnes, Tom Eirik; Wiseth, Rune; Gullestad, Lars; Aukrust, Pål; Damås, Jan Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-29)
      <p><i>Aim</i>: To evaluate the effect of interleukin-6 inhibition with tocilizumab on the cytokine network in patients with acute non-ST-elevation myocardial infarction (NSTEMI).</p> <p><i>Methods</i>: 117 patients with acute NSTEMI were randomised to an intravenous infusion of 280 mg tocilizumab or placebo prior to coronary angiography. Blood samples were obtained at baseline, at 6 consecutive ...
    • Impact of Chronic Inflammation, Assessed by hs-CRP, on the Association between Red Cell Distribution Width and Arterial Cardiovascular Disease: The Tromsø Study 

      Lappegård, Jostein; Ellingsen, Trygve; Hindberg, Kristian; Mathiesen, Ellisiv B.; Njølstad, Inger; Wilsgaard, Tom; Løchen, Maja-Lisa; Brækkan, Sigrid Kufaas; Hansen, John-Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-10)
      Red cell distribution width (RDW), a measure of variability in size of circulating erythrocytes, is associated with arterial cardiovascular disease (CVD), but the underlying mechanism remains unclear. We aimed to investigate the impact of chronic inflammation as measured by high sensitivity CRP (hs-CRP) on this relationship, and explore whether RDW could be a mediator in the causal pathway between ...
    • Nestin-expressing progenitor cells: function, identity and therapeutic implications 

      Bernal Mera, Aurora; Arranz, Lorena (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-14)
      The neuroepithelial stem cell protein, or Nestin, is a cytoskeletal intermediate filament initially characterized in neural stem cells. However, current extensive evidence obtained in in vivo models and humans shows presence of Nestin+ cells with progenitor and/or regulatory functions in a number of additional tissues, remarkably bone marrow. This review presents the current knowledge on the role ...
    • EISCAT Observation of Wave‐Like Fluctuations in Vertical Velocity of Polar Mesospheric Summer Echoes Associated With a Geomagnetic Disturbance 

      Lee, Young-Sook; Kim, Young Ha; Kim, Kyung-Chan; Kwak, Young-Sil; Sergiengko, Timothy; Kirkwood, Sheila; Johnsen, Magnar Gullikstad (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-04)
      By analyzing a data set from the European Incoherent SCATter (EISCAT) Very High Frequency (VHF) radar at Tromsø, we find that both radar reflectivity and upward ion velocity in a polar mesospheric summer echo (PMSE) layer simultaneously increased at the commencement of a local geomagnetic disturbance, which occurred at midnight on 9 July 2013. The onset of the upward velocity was followed by periodic ...
    • 3-Chloro-N′-(2-hydroxybenzylidene) benzohydrazide: An LSD1-Selective Inhibitor and Iron-Chelating Agent for Anticancer Therapy 

      Sarno, Federica; Papulino, Chiara; Franci, Gianluigi; Andersen, Jeanette hammer; Cautain, Bastien; Melardo, Colombina; Altucci, Lucia; Nebbioso, Angela; Andersen, Jeanette H. (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-07)
      Despite the discovery and development of novel therapies, cancer is still a leading cause of death worldwide. In order to grow, tumor cells require large quantities of nutrients involved in metabolic processes, and an increase in iron levels is known to contribute to cancer proliferation. Iron plays an important role in the active site of a number of proteins involved in energy metabolism, DNA ...
    • The decade construction rivalry in Russian: Using a corpus to study historical linguistics 

      Nesset, Tore; Makarova, Anastasia (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-16)
      This article addresses the diachronic development of so-called rival forms, i.e., words or grammatical constructions that appear to be synonyms, based on a detailed empirical analysis of two seemingly synonymous constructions in Russian. Corresponding to the English ‘decade construction’ <i>in the twenties</i>, Russian has two rival constructions, viz. <i>v dvadcatye gody</i> [<i>lit</i>. “in the ...
    • Small copepods matter: Population dynamics of Microsetella norvegica in a high-latitude coastal ecosystem 

      Svensen, Camilla; Antonsen, Maria Terese; Reigstad, Marit (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-04)
      We investigated the population dynamics of a small and little-studied harpacticoid copepod, <i>Microsetella norvegica</i>, in a sub-Arctic Norwegian fjord (Balsfjord 69°N). We sampled with a 90 μm mesh WP-2 net and a 20 L Go-Flo bottle and found that the WP-2 under-sampled all juvenile stages. The abundance and biomass were high, peaking in June with 9349 × 10-<sup>3</sup> ind. m<sup>−2</sup> and ...
    • Diabetes on Twitter: A Sentiment Analysis 

      Gabarron, Elia; Dorronzoro, Enrique; Rivera-Romero, Octavio; Wynn, Rolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-19)
      Background: <br>Contents published on social media have an impact on individuals and on their decision-making. Knowing the sentiment towards diabetes is fundamental to understanding the impact that such information could have on people affected with this health condition and their family members. The objective of this study is to analyze the sentiment expressed in messages on diabetes posted ...
    • Collaboration with High-Payload Industrial Robots: Simulation for Safety 

      Shu, Beibei; Sziebig, Gabor (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-12-15)
      <p>When operators and industrial robots are sharing the same task, there are multiple factors, which effect if a system is safe for the human operator or not. In general this is solved by introducing Collaborative Robot for cooperation, but what happens when we would extend our already existing production facilities with newer comfort features?</p> <p>In this paper we propose to include industrial ...
    • Seasonal variation in the thermal responses to changing environmental temperature in the world's northernmost land bird 

      Nord, Andreas; Folkow, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-01-10)
      Arctic homeotherms counter challenges at high latitudes using a combination of seasonal adjustments in pelage/plumage, fat deposition and intricate thermoregulatory adaptations. However, there are still gaps in our understanding of their thermal responses to cold, particularly in Arctic birds. Here, we have studied the potential use of local heterothermy (i.e. tissue cooling that can contribute to ...
    • Factors Associated with High Weight Gain and Obesity Duration: The Norwegian Women and Cancer (NOWAC) Study 

      da Silva, Marisa Eleonor; Weiderpass, Elisabete; Licaj, Idlir; Rylander, Charlotta (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-12)
      <i>Aim:</i> To identify factors associated with high weight gain and obesity duration in a representative sample of Norwegian women.<p> <p><i>Methods</i>: 66,618 Norwegian women aged 34–70 years at baseline were included in the analysis. Baseline and follow-up questionnaires completed in 1991–2011 provided information on height, weight as well as sociodemographic, lifestyle and reproductive ...
    • The effect of Nordmøre grid length and angle on codend entry of bycatch fish species and shrimp catches 

      Larsen, Roger B.; Sistiaga, Manu Berrondo; Herrmann, Bent; Brinkhof, Jesse; Tatone, Ivan; Santos, Juan (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-18)
      The Nordmøre grid is regarded as an efficient bycatch reducing device and is used in various shrimp trawl fisheries globally. However, in some shrimp fisheries bycatch remains a problem that seriously impacts commercial trawl activities. This study tested and compared the performance of two versions of the Nordmøre grid in the Northeast Arctic Deepwater Shrimp (Pandalus borealis) fishery; a standard ...
    • Investigating fish behavioural responses to LED lights in trawls and potential applications for bycatch reduction in the Nephrops-directed fishery 

      Melli, Valentina; Krag, Ludvig Ahm; Herrmann, Bent; Karlsen, Junita Diana (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-04-18)
      Light-emitting diodes (LEDs) have been tested in trawl fisheries to reduce the bycatch of unwanted species through behavioural stimulation. Previous studies used LED lights to either highlight escaping routes or increase the contact rate with square-mesh panels. However, phototactic responses (moving towards or away from light sources) to LED lights could also be exploited to separate species during ...
    • CREELSELECT—A method for determining the optimal creel mesh: Case study on Norway lobster (Nephrops norvegicus) fishery in the Mediterranean Sea 

      Brčić, Jure; Herrmann, Bent; Mašanović, Marina; Šifner, Svjetlana Krstulović; Škeljo, Frane (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-03-31)
      In the laboratory, we investigated which sizes of <i>Nephrops</i> (<i>Nephrops norvegicus</i>) could pass through the meshes of different size and shape to establish a predictive model for the creels size selectivity. Predictions agreed well with the results from experimental fishing, demonstrating the reliability of this simple method. <i>Nephrops</i> minimum target size is 20 mm carapace length ...
    • The efficiency of sieve-panels for bycatch separation in Nephrops trawls 

      Santos, Juan; Herrmann, Bent; Mieske, Bernd; Krag, Ludvig Ahm; Haase, Stefanie; Stepputtis, Daniel (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-11)
      This study investigated the efficiency of a sieve‐panel concept, intended to separate bycatch species from <i>Nephrops</i> (Norway lobster) in a trawl gear via mechanical and behavioural means. Four different designs of varying panel mesh size or inclination were tested in experimental fishing. For each design, the length‐dependent sieving efficiency, defined as the fraction of <i>Nephrops</i> or ...