Now showing items 4681-4700 of 36554

    • Prognostic factors and independent validation of a risk stratification model in octogenarian patients irradiated for brain metastases 

      Nieder, Carsten; Dalhaug, Astrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-25)
      Background/Aim: This study aimed at validation of a prognostic model, originally developed by Rades et al., in an age-restricted, particularly vulnerable subgroup of patients with brain metastases, because international variations in clinical practice and survival outcomes may impact on the performance of survival prediction tools. Patients and Methods: Retrospectively, data from a single institution ...
    • Independent validation of a risk stratification model predicting survival in elderly patients irradiated for bone metastases 

      Nieder, Carsten; Stanisavljevic, Luka; Mannsåker, Bård; Haukland, Ellinor Christin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02)
      Background/Aim: Many patients with bone metastases receive palliative radiotherapy. However, treatment personalization tools are needed, due to heterogeneous survival. The aim of this study was to analyze the validity of the prognostic survival model, originally developed by Rades et al., because international variations in clinical practice and survival outcomes may impact on the performance of ...
    • The LabPS score: Inexpensive, Fast, and Site-agnostic Survival Prediction 

      Nieder, Carsten; Haukland, Ellinor Christin; Mannsåker, Bård; Dalhaug, Astrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-04)
      Objectives: To provide a widely applicable, blood-biomarker-based and performance-status-based prognostic model, which predicts the survival of patients undergoing palliative non-brain radiotherapy. This model has already been examined in a cohort of patients treated for brain metastases and performed well.<p> <p>Methods: This was a retrospective single-institution analysis of 375 patients, ...
    • Patterns of Care and Survival in Cancer Patients with Brain Metastases Receiving Immune Checkpoint Inhibitors 

      Nieder, Carsten; Mannsåker, Bård; Stanisavljevic, Luka; Haukland, Ellinor Christin (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-15)
      Introduction: Immune checkpoint inhibitors (ICIs) have become a mainstay of treatment for different cancer types. The purpose of this study was to evaluate patterns of care and overall survival (OS) after diagnosis of brain metastases in patients managed with ICI as component of care. Methods: This was a retrospective cohort study. Fifty patients were included (34 with brain metastases at first ...
    • Impact of the von Willebrand factor-ADAMTS-13 axis on the risk of future venous thromboembolism 

      Edvardsen, Magnus; Hansen, Ellen-Sofie; Ueland, Thor; Aukrust, Pål; Brækkan, Sigrid Kufaas; Morelli, Vania Maris; Hansen, John Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-01)
      Background - von Willebrand factor (VWF) and its cleaving protease, ADAMTS-13, form a pivotal axis that regulates hemostasis. However, the role of the VWF-ADAMTS-13 axis in the risk of future venous thromboembolism (VTE) is unknown.<p> <p>Objectives - To investigate whether plasma ADAMTS-13 levels and an imbalance with VWF levels, assessed as the VWF/ADAMTS-13 ratio, are associated with the risk ...
    • Complement factors B, D, C3bBbP and risk of future venous thromboembolism 

      Skjeflo, Espen Waage; Evensen, Line Holtet; Jensen, Søren Beck; Latysheva, Nadezhda; Michelsen, Annika Elisabet; Ueland, Thor; Brækkan, Sigrid Kufaas; Hindberg, Kristian Dalsbø; Snir, Omri; Mollnes, Tom Eirik; Hansen, John Bjarne (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-07)
      The complement system appears to be involved in the pathogenesis of venous thromboembolism (VTE).<p> <p>We investigated the association of complement factors (CF) B, D, and the alternative pathway convertase, C3bBbP, measured at inclusion, with the risk of future VTE in a nested case-control study; 380 VTE patients and 804 age- and sex-matched controls derived from the Tromsø study. Odds ratios ...
    • ‘PISA effects’ on Norwegian education. A critical realist perspective 

      Bringeland, Terje André (Doctoral thesis; Doktorgradsavhandling, 2024-02-09)
      <p>The objective of the thesis is to examine, from a critical realist perspective and by using Margaret Archer’s conceptual framework, possible effects that the Programme for International Student Assessment (PISA) test has on the Norwegian education system and on school personnel. The intention has been to reconceptualise the notion of ‘PISA effects’ both at the systemic (macro) and individual ...
    • PISA and Teachers’ Reflexivities. A Mixed Methods Case Study 

      Bringeland, Terje André; Skinningsrud, Tone (Journal article; Tidsskriftartikkel, 2024-01-12)
      Neoliberal educational reforms include extensive use of standardized tests. We examine the Program for International Student Assessment (PISA) initiated and developed by the Organization for Economic Cooperation and Development (OECD). Examining previous research on teachers’ reactions to neoliberal reforms altering their work context, we have identified three theoretical frameworks in use: labour ...
    • Psychoactive substances and previous hospital admissions, triage and length of stay in rural injuries: a prospective observational study 

      Wilson, Thomas; Wisborg, Torben; Vindenes, Vigdis; Jamt, Ragnhild Elén Gjulem; Bogstrand, Stig Tore (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-27)
      Background - Patients admitted to hospital after an injury are often found to have used psychoactive substances prior to the injury. The aim of this study was to investigate the associations between psychoactive substances (alcohol, psychoactive medicinal drugs and illicit drugs) and previous hospital admissions, triage and length of stay in the arctic Norwegian county of Finnmark.<p> <p>Methods ...
    • CSF, Blood, and MRI Biomarkers in Skogholt’s Disease—A Rare Neurodegenerative Disease in a Norwegian Kindred 

      Aspli, Klaus Thanke; Aaseth, Jan; Holmøy, Trygve; Blennow, Kaj; Zetterberg, Henrik; Kirsebom, Bjørn-Eivind Seljelid; Fladby, Tormod; Selnes, Per (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-10-26)
      Skogholt’s disease is a rare neurological disorder that is only observed in a small Norwegian kindred. It typically manifests in adulthood with uncharacteristic neurological symptoms from both the peripheral and central nervous systems. The etiology of the observed cerebral white matter lesions and peripheral myelin pathology is unclear. Increased cerebrospinal fluid (CSF) concentrations of protein ...
    • Sharpness of some Hardy-type inequalities 

      Persson, Lars-Erik; Samko, Natasha Gabatsuyevna; Tephnadze, George (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-04)
      The current status concerning Hardy-type inequalities with sharp constants is presented and described in a unified convexity way. In particular, it is then natural to replace the Lebesgue measure dx with the Haar measure . There are also derived some new two-sided Hardy-type inequalities for monotone functions, where not only the two constants are sharp but also the involved function spaces are ...
    • Performance Analysis of Bidirectional Multi-Hop Vehicle-to-Vehicle Visible Light Communication 

      Refas, Souad; Acheli, Dalila; Yahia, Selma; Meraihi, Yassine; Ramdane-Cherif, Amar; Van, Nhan Vo; Ho, Tu Dac (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-14)
      Vehicular visible light communication (VVLC) has emerged as a promising field of research, garnering considerable attention from scientists and researchers. VVLC offers a potential solution to enable connectivity and communication between travelling vehicles along the road by using their existing headlights (HLs) and taillights (TLs) as wireless transmitters and integrating photodetectors (PDs) ...
    • Skole–hjem-samarbeid i videregående skole: autonomistøtte i elevenes dannings- og utdanningsprosess 

      Vedeler, Gørill Warvik; Strandbu, Astrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-13)
      I denne artikkelen utforsker vi erfaringer med skole–hjem-samarbeid i videregående skole. Vi inviterte 113 tidligere videregåendeskoleelever til å delta i dialogkaféer for å belyse skole–hjem-samarbeid som pedagogisk praksis i videregående skole. Resultatene avdekket en ambivalens i opplevelsen av skole–hjem-samarbeid, der elevene uttrykker at de ønsker å være selvstendige samtidig som de har behov ...
    • Reconstruction of electron precipitation spectra at the top of the upper atmosphere using 427.8 nm auroral images 

      Robert, Elisa; Barthélemy, Mathieu; Cessateur, Gaël; Woelfflé, Angélique; Lamy, Hervé; Bouriat, Simon; Johnsen, Magnar Gullikstad; Brändström, Urban; biree, lionel (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-13)
      We present an innovative method to reconstruct the characteristics of precipitated electrons in auroral regions from optical measurements. This method is based on an optimization implemented between numerical simulations of the Transsolo code and tomographic maps made from the Auroral Large Imaging System (ALIS) network. We focus on the Volume Emission Rate (VER) of the blue line 1NG 427.8 nm, which ...
    • Enhanced performance of microbial fuel cells using electrochemically treated carbon felt anode 

      Poureshghi, Fatemeh; Calay, Rajnish K; Das, Subhashis (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-10)
      The microbial fuel cell (MFC) technology is emerging as an effective technology for wastewater treatment to remove and detect many pollutants and simultaneously generate power. The anode is an essential component for bacterial attachment and extracellular electron transfer (EET). Thus, anode performance is critical for improving an MFC system's overall performance. Materials that are electronically ...
    • Platelet and mitochondrial RNA is decreased in plasma-derived extracellular vesicles in women with preeclampsia—an exploratory study 

      Lekva, Tove; Sundaram, Arvind; Roland, Marie Cecilie; Åsheim, June; Michelsen, Annika Elisabet; Norwitz, Errol R.; Aukrust, Pål; Gilfillan, Gregor; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-23)
      Background - Circulating extracellular vesicles (EVs) are increased in preeclampsia (PE) and are associated with severity and progression. We examined in this exploratory cohort study if the mRNAs and long noncoding RNAs (lncRNAs) in plasma-derived EVs were dysregulated in PE compared to normal pregnancy and display different temporal patterns during gestation.<p> <p>Methods - We isolated EVs ...
    • Determinants of practice for providing decision coaching to facilitate informed values-based decision-making: Protocol for a mixed-methods systematic review 

      Berger-Höger, Birte; Lewis, Krystina B.; Cherry, Katherine; Finderup, Jeanette; Gunderson, Janet; Kaden, Jana; Kienlin, Simone Maria; Rahn, Anne C.; Sikora, Lindsey; Stacey, Dawn; Steckelberg, Anke; Zhao, Junqiang (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-15)
      Introduction - Decision coaching is a non-directive approach to support patients to prepare for making health decisions. It is used to facilitate patients’ involvement in informed values-based decision-making and use of evidence-based health information. A recent systematic review revealed low certainty evidence for its effectiveness with and without evidence-based information. However, there may ...
    • Differences in mammography screening attendance among non-Western immigrants in Denmark, Finland, Iceland and Norway 

      Njor, Sisse Helle; Heinävaara, Sirpa; Stefansdóttir, Hrefna; Nygård, Mari; Guðmundsdóttir, Eva María; Bhargava, Sameer; Leivonen, Aku; Campbell, Suzanne; Søborg, Bo; Hofvind, Solveig Sand-Hanssen; Sarkeala, Tytti; Vejborg, Ilse; Lamminmäki, Maarit (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-22)
      Several studies have shown that attendance rates are lower among non-Western immigrants than among natives. As the Nordic countries have quite similar health systems and populations but also differences in the organisation of their organised mammography screening programmes, differences in attendance rates could highlight organisational factors that might increase the attendance rates. Mammography ...
    • Cerebrospinal fluid neurofilament light chain mediates age-associated lower learning and memory in healthy adults 

      Hemminghyth, Mathilde Suhr; Chwiszczuk, Luiza; Breitve, Monica Haraldseid; Gisladottir, Berglind; Grøntvedt, Gøril Rolfseng; Nakling, Arne Exner; Rongve, Arvid; Fladby, Tormod; Kirsebom, Bjørn-Eivind Seljelid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-27)
      Multiple cognitive domains, including learning, memory, and psychomotor speed, show significant reductions with age. Likewise, several cerebrospinal fluid (CSF) neurodegenerative biomarkers, including total tau (t-tau, a marker of neuronal body injury) and neurofilament light chain (NfL, a marker of axonal injury) show age-related increases in normal aging. In the current study, we aimed to investigate ...
    • The current status of environmental forensic science in the member institutes of the European Network of Forensic Science Institutes (ENFSI) 

      Mäkelä, Tuukka; Huhtala, Sami; Lindqvist, Mimmi A.; Bucht, Rebecca (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-04)
      The paper presents the results of a questionnaire survey carried out by The Forensic laboratory of the National Bureau of Investigation (NBI-FL), aiming to get an overview of the current status of environmental forensic science (EFS) and environmental crimes investigation in the European Network of Forensic Science Institutes (ENFSI). A questionnaire was sent out to 71 ENFSI member institutes and ...