Viser treff 15641-15660 av 37183

    • Circulating regulators of the wingless pathway in precapillary pulmonary hypertension 

      Ueland, Thor; Abraityte, Aurelija; Norum, Hilde; Varathalingam, Sharanga; Gullestad, Lars; Aukrust, Pål; Andreassen, Arne K. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-08)
      Background and objective - Dysregulated Wnt signalling has been implicated in pulmonary hypertension (PH). We hypothesized that plasma levels of secreted Wnt proteins would be increased in patients with precapillary PH, correlate with indices of vascular resistance and cardiac function and give information on long-term prognosis.<p> <p>Methods - We measured the Wnt ligand Wnt5a and secreted Wnt ...
    • On the correction of temperatures derived from meteor wind radars due to geomagnetic activity 

      Hall, Chris; Johnsen, Magnar Gullikstad (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-12)
      Radars used to observe meteor trails in the mesosphere deliver information on winds and temperature. Use of these radars is becoming a standard method for determining mesospheric dynamics and temperatures worldwide due to relatively low costs and ease of deployment. However, recent studies have revealed that temperatures may be overestimated in conditions such as high geomagnetic activity. The effect ...
    • Salmon farming in the North – Regulating societal and environmental impacts 

      Solås, Ann-Magnhild; Kvalvik, Ingrid; Simonsen, Knud; Thorarinsdottir, Ragnheidur Inga; Young, Nathan; Johnsen, Jahn Petter; Sønvinsen, Signe A.; Robertsen, Roy (Research report; Forskningsrapport, 2020-12-31)
      Salmon farming is a rapidly growing industry in the North and its sustainable development depends on adequate governance. We have assessed the governance systems for salmon farming in four northern countries, Canada, the Faroe Islands, Iceland, and Norway. In all the countries, the industry is marked by controversies, linked to the environmental and societal impacts of its activities. The question ...
    • Salmon farming in the North: How do we regulate growth? 

      Solås, Ann-Magnhild; Kvalvik, Ingrid; Robertsen, Roy; Young, Nathan; Thorarinsdottir, Ragnheidur Inga; Simonsen, Knud; Sønvisen, Signe Annie; Johnsen, Jahn Petter (Journal article; Tidsskriftartikkel, 2021)
      Aquaculture has become a major part of global food production, and according to the UN Food and Agriculture Organization, it is now the fastest growing animal food-producing industry. In the North, further growth in salmon farming is expected. What mechanisms are in place to regulate this growth?
    • Cognitive States in Third Language Acquisition and Beyond: Theoretical and Methodological Paths Forward 

      Soares, Sergio Miguel Pereira; Rothman, Jason (Journal article; Tidsskriftartikkel, 2021-03-01)
    • Liking and Perceived Safety across Judgments of Distinct Instances of a Category of Activity 

      Stephensen, Matthew; Martiny-Huenger, Torsten (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-03)
      Prior research on the affect heuristic demonstrated that the more a person likes an object or activity, the safer and more valuable it is judged to be. That relation was found when judging stimuli at the categorical level (e.g., nuclear power, airplane travel, heart surgery). Yet risk judgments and decisions usually pertain to specific instances of an object or activity rather than their categorical ...
    • Don't go chasing the ghosts of the past: habitat selection and site fidelity during calving in an Arctic ungulate 

      Paulsen, Ingrid M.; Soininen, Eeva M; Ravolainen, Virve; Loe, Leif Egil; Hansen, Brage Bremset; Irvine, Justin R; Stien, Audun; Ropstad, Erik; Veiberg, Vebjørn; Fuglei, Eva; Pedersen, Åshild Ønvik (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-01)
      Predator avoidance and food availability are both factors known to influence habitat selection and site fidelity around calving in caribou and reindeer. Here, we assess habitat selection and site fidelity during the calving period in the solitary, Arctic Svalbard reindeer Rangifer tarandus platyrhynchus, which is subject to limited predation risk and human disturbance. In this largely predator-free ...
    • Assessment of the risk to Norwegian biodiversity from import and keeping of crustaceans in freshwater aquaria. Scientific Opinion of the Panel on Alien Organisms and Trade in Endangered Species of the Norwegian Scientific Committee for Food and Environment 

      Velle, Gaute; Edsman, Lennart; Evangelista, Charlotte; Johnsen, Stein Ivar; Malmstrøm, Martin; Vrålstad, Trude; de Boer, Hugo; Eldegard, Katrine; Hindar, Kjetil; Hole, Lars Robert; Kausrud, Kyrre Linné; Järnegren, Johanna; Måren, Inger Elisabeth; Nilsen, Erlend Birkeland; Rueness, Eli Knispel; Thorstad, Eva Bonsak; Nielsen, Anders (Research report; Forskningsrapport, 2021)
      The Norwegian Scientific Committee for Food and Environment (VKM) was requested by the Norwegian Environment Agency to assess the risk of negative impacts to biodiversity in Norway resulting from import of crustacean decapods for keeping in freshwater aquariums.<p> <p>VKM was asked to 1) list species of crayfish, crabs and shrimps that are currently kept in freshwater aquaria in Norway, and ...
    • First record of plastic debris in the stomach of a hooded seal pup from the Greenland Sea 

      Pinzone, Marianna; Nordøy, Erling Sverre; Eppe, Gauthier; Malherbe, Cédric; Das, Krishna; Collard, France (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-14)
      Plastic debris is globally found around the world and the remote Arctic is no exception. Arctic true seals are sentinel species of marine pollution and represent the link between marine food webs and Arctic apex predators like polar bears and humans. With regard to true seals, ingested macroplastics have never been reported in an Arctic species. We harvested 10 harp seals Pagophilus groenlandicus ...
    • Explaining subjective social status in two countries: The relative importance of education, occupation, income and childhood circumstances 

      Lindberg, Marie Hella; Chen, Gang; Olsen, Jan Abel; Abelsen, Birgit (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-03)
      In the literature on social inequalities in health, subjective socioeconomic position (SEP) is increasingly applied as a determinant of health, motivated by the hypothesis that having a high subjective SEP is health-enhancing. However, the relative importance of determinants of subjective SEP is not well understood. Objective SEP indicators, such as education, occupation and income, are assumed to ...
    • Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates 

      Paulsen, Marianne Hagensen; Engqvist, Magnus; Ausbacher, Dominik; Anderssen, Trude; Langer, Manuel Karl; Haug, Tor; Morello, Glenn Robert; Liikanen, Laura; Blencke, Hans-Matti; Isaksson, Johan; Juskewitz, Eric; Bayer, Annette; Strøm, Morten B. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-27)
      We report a series of synthetic cationic amphipathic barbiturates inspired by the pharmacophore model of small antimicrobial peptides (AMPs) and the marine antimicrobials eusynstyelamides. These N,N′-dialkylated-5,5-disubstituted barbiturates consist of an achiral barbiturate scaffold with two cationic groups and two lipophilic side chains. Minimum inhibitory concentrations of 2–8 μg/mL were achieved ...
    • Rifaximin or Saccharomyces boulardii in heart failure with reduced ejection fraction: Results from the randomized GutHeart trial 

      Awoyemi, Ayodeji Olawale; Mayerhofer, Cristiane; Felix, Alex S.; Hov, Johannes Espolin Roksund; Moscavitch, Samuel D.; Lappegård, Knut Tore; Hovland, Anders; Halvorsen, Sigrun; Halvorsen, Bente; Gregersen, Ida; Svardal, Asbjørn M.; Berge, Rolf Kristian; Hansen, Simen Hyll; Götz, Alexandra; Holm, Kristian; Aukrust, Pål; Åkra, Sissel; Seljeflot, Ingebjørg; Solheim, Svein; Lorenzo, Andrea; Gullestad, Lars; Trøseid, Marius; Broch, Kaspar (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-28)
      Background - The gut microbiota represents a potential treatment target in heart failure (HF) through microbial metabolites such as trimethylamine N-oxide (TMAO) and systemic inflammation. Treatment with the probiotic yeast Saccharomyces boulardii have been suggested to improve left ventricular ejection fraction (LVEF).<p> <p>Methods - In a multicentre, prospective randomized open label, blinded ...
    • Adiponectin Is Related to Cardiovascular Risk in Severe Mental Illness Independent of Antipsychotic Treatment 

      Reponen, Elina Johanna; Tesli, Martin Steen; Dieset, Ingrid; Steen, Nils Eiel; Vedal, Trude Seselie Jahr; Szabo, Attila; Werner, Maren Caroline Frogner; Lunding, Synve Hoffart; Johansen, Ingrid Torp; Rødevand, Linn; Andreassen, Ole Andreas; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-28)
      Background: Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental illnesses (SMI) associated with elevated cardiovascular disease (CVD) risk, including obesity. Leptin and adiponectin are secreted by adipose tissue, with pro- and anti-inflammatory properties, respectively. The second generation antipsychotics (AP) olanzapine, clozapine, and quetiapine have been associated with high leptin ...
    • Concentrations and geographical patterns of persistent organic pollutants (POPs) in meat from semi-domesticated reindeer (Rangifer tarandus tarandus L.) in Norway 

      Hassan, Ammar Ali; Nøst, Therese Haugdahl; Brustad, Magritt; Sandanger, Torkjel M. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-07-29)
      The study aimed at investigating the concentrations and geographical patterns of 11 polychlorinated biphenyls (PCBs) and 15 organochlorine pesticides (OCPs) in reindeer muscle samples (n = 100) collected from 10 grazing districts in Norway, 2009. Concentrations were examined for patterns related to geographical region as well as age and sex of animals. Concentrations measured for PCBs and OCPs in ...
    • GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility 

      Eriksson, Daniel; Røyrvik, Ellen Christine; Aranda-Guillen, Maribel; Berger, Amund Holte; Landegren, Nils; Artaza, Haydee; Hallgren, Åsa; Grytaas, Marianne; Strøm, Sara; Bratland, Eirik; Botusan, Ileana; Oftedal, Bergithe Eikeland; Breivik, Lars Ertesvåg; Vaudel, Marc; Helgeland, Øyvind; Falorni, Alberto; Jørgensen, Anders Palmstrøm; Hulting, Anna-Lena; Svartberg, Johan; Ekwall, Olov; Fougner, Kristian J; Wahlberg, Jeanette; Nedrebø, Bjørn Gunnar; Dahlqvist, Per; Study group, Norwegian Addison Registry; Study Group, Swedish Addison Registry; Knappskog, Per Morten; Wolff, Anette Susanne Bøe; Bensing, Sophie; Johansson, Stefan; Kämpe, Olof; Husebye, Eystein Sverre (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-02-11)
      Autoimmune Addison’s disease (AAD) is characterized by the autoimmune destruction of the adrenal cortex. Low prevalence and complex inheritance have long hindered successful genetic studies. We here report the first genome-wide association study on AAD, which identifies nine independent risk loci (P < 5 × 10−8). In addition to loci implicated in lymphocyte function and development shared with other ...
    • Organization and orchestration of male rat sexual behavior 

      Huijgens, Patty Thalia (Doctoral thesis; Doktorgradsavhandling, 2021-09-07)
      Sexual behavior is innately motivated and rewarding. The underlying neurobiological mechanisms of sexual motivation, copulation, and sexual reward have not been completely unraveled. This thesis gives insight in the structure, organization, and neurobiological orchestration of male rat sexual behavior. The research presented in this thesis demonstrates that a more extensive behavioral annotation ...
    • Glacial and environmental changes in northern Svalbard over the last 16.3 ka inferred from neodymium isotopes 

      Jang, Kwangchul; Ahn, Youngkyu; Joe, Young Jin; Braun, Carmen; Joo, Young Ji; Kim, Jung-Hyun; Bayon, Germain; Forwick, Matthias; Vogt, Christoph; Nam, Seung-Il (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-05)
      The reconstruction of past ice sheet extents and dynamics in polar regions is essential for understanding the global climate system and obtaining more reliable predictions of future climate change. Here, we present a multi-proxy dataset integrating the Nd isotopic compositions (εNd) of paired detrital and authigenic Fe oxide fractions, grain size distributions, organic geochemistry, and mineral ...
    • Transport Barriers and the Retention of Calanus finmarchicus on the Lofoten Shelf in Early Spring 

      Dong, Huizi; Zhou, Meng; Hu, Ziyuan; Zhang, Zhaoru; Zhong, Yisen; Basedow, Sünnje Linnéa; Smith Jr., Walker O. (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-02)
      Large aggregations of the copepod Calanus finmarchicus occur each spring in the shelf-slope-oceanic regions off the Lofoten-Vesterålen Islands where productive fisheries have traditionally supported local economies. The retention and off-shelf transport of populations of C. finmarchicus populations were studied by analyzing ocean color remote sensing, satellite altimetry data, and Lagrangian Coherent ...
    • Swimming performance of subarctic Calanus spp. facing downward currents 

      Weidberg, Nicholas; DiBacco, Claudio; Pezzola, Caterina; Rebiffe, Etienne; Basedow, Sünnje Linnéa (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-29)
      Calanoid copepods dominate mesozooplankton communities in temperate and Nordic seas. The ability of copepods to remain and feed in productive surface waters depends on their ability to overcome downward flows. In this study, we assessed the swimming performance of subarctic Calanus spp. and tested how the copepods can retain their vertical position in a representative range of downward currents ...
    • Family involvement in the intensive care unit in four Nordic countries 

      Frivold, Gro; Ågård, Anne Sophie; Jensen, Hanne Irene; Åkerman, Eva; Fossum, Mariann; Alfheim, Hanne Birgit; Rasi, Matias; Lind, Ranveig (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-17)
      Background - Relevance to clinical practice The findings from the study highlighting family involvement, high-quality communication and flexible visiting policy as central aspects of family care may inspire clinicians to identify aspects of everyday family care in their ICUs calling for further improvement.<p> <p>Aims and objectives - To describe family involvement, communication practices and ...