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Provider decision regret - a useful method for analysis of palliative thoracic re-irradiation for lung cancer?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-30)Background - The overall usefulness of palliative thoracic re-irradiation depends on the balance between efficacy, survival, and toxicity, and is difficult to judge from previous studies. In the absence of patient-reported data, we developed a method for provider decision regret that addresses the question “would we re-irradiate this patient again in light of the known outcome?” Furthermore, we ... -
Symptom burden in patients with oligometastases at the start of palliative radiotherapy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-04)Background/Aim: Recent studies suggested that patients with oligometastases have a better prognosis compared with those who have widespread dissemination. In both groups, radiotherapy is a commonly applied treatment. Patient-reported symptoms might depend on the burden of disease. Possibly, oligometastatic patients report lower scores for symptoms, such as fatigue or reduced appetite, which tend to ... -
Long-term survival results after treatment for oligometastatic brain disease
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-04)Aim - The aim of this study was to characterize the survival results of patients with up to four brain metastases after intense local therapy (primary surgery or stereotactic radiotherapy) if extracranial metastases were absent or limited to one site, e.g. the lungs.<p> <p>Background - Oligometastatic disease has repeatedly been reported to convey a favorable prognosis.<p> <p>Material and ... -
Direct angiography demonstrates equal 8-12 years patency rates of radial artery and saphenous vein grafts
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-30)Objectives: The benefits of coronary artery bypass surgery depend on lasting graft patency. To aid rational graft selection, the relative long-term merits of radial artery and saphenous vein grafts need to be determined by a gold standard method and with minimal clinically driven selection bias. Methods: The patency rates of various conduits were determined by direct angiography in 76 patients from ... -
No significant histological or ultrastructural tendinosis changes in the hamstring tendon in patients with mild to moderate osteoarthritis of the knee?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-05)Purpose - To investigate the periarticular degenerative changes of the knee joint in association with osteoarthritis (OA). More tendinosis was expected to be found in the semitendinosus tendon in patients with knee OA than in patients without knee OA.<p> <p>Methods - Samples from 41 patients were included between January 2016 and October 2017. Twenty-one patients median age 53 (33–63) years with ... -
Atrial fibrillation, venous thromboembolism, ischemic stroke, and all-cause mortality: The Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-06)Background Atrial fibrillation (AF) is associated with increased risk of ischemic stroke and all‐cause mortality. Patients with AF are also at increased risk of venous thromboembolism (VTE), but information on how AF impacts VTE‐related mortality is scarce. Objectives - To investigate the impact of AF on all‐cause mortality in subjects with and without a thromboembolic event (VTE or ischemic ... -
D-dimer as a stand-alone test to rule out deep vein thrombosis
(Journal article; Tidsskriftartikkel, 2020-04-25)Background - Current guidelines recommend the use of clinical decision rules, such as Wells score, in combination with D-dimer to assess the need for objective imaging to rule out deep vein thrombosis (DVT). However, the clinical decision rule has limitations, and use of D-dimer as a stand-alone test has been suggested.<p> <p>Objective - We aimed to assess the safety and efficiency of D-dimer as ... -
Nutritional status, sarcopenia, gastrointestinal symptoms and quality of life after gastrectomy for cancer - A cross-sectional pilot study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-06)<i>Background and aims</i> - Gastrointestinal (GI) symptoms, malabsorption, reduced food intake and weight loss are common sequela of gastrectomy. This can result in malnutrition with a subsequent prolonged recovery, reduced physical functioning and deteriorated quality of life (QoL). Few studies have investigated the relationship between GI-symptoms, QoL and malnutrition in long-term survivors of ... -
20 Years of Nordic tourism experience research: a review and future research agenda
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-12-12)During the past decades, tourism experience research has become a topical theme among Nordic researchers and in international tourism literature. This review provides an overview of the main themes of Nordic experience research, addresses the antecedents of tourism experiences, namely tourists’ emotional and interest regimes, and tourism experience outcomes, namely the value of tourism. Furthermore, ... -
L3 acquisition and crosslinguistic influence as co-activation. Response to commentaries on the keynote “Microvariation in multilingual situations: The importance of property-by-property acquisition
(Journal article; Tidsskriftartikkel; Peer reviewed, 2021-04-10)I would first of all like to thank the many authors who have provided commentaries on my keynote article ‘Microvariation in multilingual situations: The importance of property-by-property acquisition’ (Westergaard, 2021a). The keynote has generated significant and stimulating debate about central issues on crosslinguistic influence in multilingual language acquisition, and I find it especially welcome ... -
Lenking og kobling i Historisk befolkningsregister
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-14)Historisk befolkningsregister, HBR, er et register over den norske befolkningen fra 1801 frem til Det sentrale folkeregisteret fra 1964. Det lages ved å lenke sammen personforekomster av samme person i folketellinger og kirkebøker og koble sammen nære familiemedlemmer.<br><br> Vi viser hvordan algoritmer brukes til å finne lenker og koblinger. Vi har funnet familierelasjoner i alle de nominative ... -
The fraction of lung cancer attributable to smoking in the Norwegian Women and Cancer (NOWAC) Study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-10-27)<i>Background</i> - We examined the association between active and passive smoking and lung cancer risk and the population attributable fraction (PAF) of lung cancer due to active smoking, in the Norwegian Women and Cancer Study, a nationally representative prospective cohort study.<br><br> <i>Methods</i> - We followed 142,508 women, aged 31–70 years, who completed a baseline questionnaire between ... -
Leisure physical exercise and creatine kinase activity. The Tromsø study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-08-16)Creatine kinase (CK) is an enzyme catalyzing energy reaction in muscle cells and has proven to modify cardiovascular risks. The influence of skeletal muscle activity on CK concentrations is a potential study confounder but is mainly reported in connection with sport activities. This study investigated the association between leisure physical exercise and CK and estimated the effect of physical ... -
Acquiring sub-efficient and efficient variants of novel means by integrating information from multiple social models in preschoolers
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-08)Sub-efficient action routines often represent culture-specific conventional forms of actions that belong to the repertoire of cultural knowledge shared by a social group. Children readily acquire such sub-efficient routines from social demonstrations and often preserve them in their action repertoire despite encountering more efficient alternatives. This suggests that they can treat sub-efficient ... -
Management strategies for children with COVID-19: ESPR practical recommendations
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-03)During the outbreak of the COVID-19 pandemic, guidelines have been issued by international, national and local authorities to address management and the need for preparedness. Children with COVID-19 differ from adults in that they are less often and less severely affected. Additional precautions required in the management of children address their increased radiosensitivity, need for accompanying ... -
BK polyomavirus evades innate immune sensing by disrupting the mitochondrial network and promotes mitophagy
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-06-10)Immune escape contributes to viral persistence, yet little is known about human polyomaviruses. BK-polyomavirus (BKPyV) asymptomatically infects 90% of humans but causes premature allograft failure in kidney transplant patients. Despite virus-specific T cells and neutralizing antibodies, BKPyV persists in kidneys and evades immune control as evidenced by urinary shedding in immunocompetent individuals. ... -
Populismens retorikk: trussel eller ressurs for deliberativt demokrati?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020)Å deliberere (eng: to deliberate) vil si å drøfte noe, for eksempel sannheten av en påstand eller riktigheten av en handling, ved å vurdere grunner for og imot. At en demokratiteori er «deliberativ», betyr som minimum at den tildeler offentlig politisk diskusjon en eller flere sentrale funksjoner i et velfungerende demokrati. Til forskjell fra «aggregative» modeller som fokuserer på stemmegiving ... -
Healthy lifestyle and the risk of lymphoma in the European Prospective Investigation into Cancer and Nutrition study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-03-16)Limited evidence exists on the role of modifiable lifestyle factors on the risk of lymphoma. In this work, the associations between adherence to healthy lifestyles and risks of Hodgkin lymphoma (HL) and non‐Hodgkin lymphoma (NHL) were evaluated in a large‐scale European prospective cohort. Within the European Prospective Investigation into Cancer and Nutrition (EPIC), 2,999 incident lymphoma cases ... -
Electronic cigarettes and health with special focus on cardiovascular effects: position paper of the European Association of Preventive Cardiology (EAPC)
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-07-17)Background - Tobacco use is the single largest preventable risk factor for premature death of non-communicable diseases and the second leading cause of cardiovascular disease. In response to the harmful effects of tobacco smoking, the use of electronic cigarettes (e-cigarettes) has emerged and gained significant popularity over the past 15 years. E-cigarettes are promoted as safe alternatives for ... -
Cyclostratigraphic age constraining for Quaternary sediments in the Makarov Basin of the western Arctic Ocean using manganese variability
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-09-26)The Quaternary paleoenvironmental history of the Arctic Ocean remains uncertain, mainly due to the limited chronological constraints, especially beyond the 14C dating limits of accelerator mass spectrometry (AMS). The difficulty in establishing reliable chronostratigraphies is mainly attributed to low sedimentation rates and diagenetic sediment changes, resulting in very poor preservation of ...