Viser treff 18441-18460 av 36353

    • Svalbard on the (Post-) Soviet Screen 

      Rogatchevski, Andrei (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-01)
      A selection of Soviet/Russian and Norwegian documentary and feature films about Svalbard is analysed to account for the recurrent issues raised in cinematic representations of the archipelago. Such issues primarily include Svalbard’s ownership and demilitarization, as well as the role that women – and Russia – play in the region. The subject of these representations’ verisimilitude is also discussed. ...
    • Impact of mucin on drug diffusion: Development of a straightforward in vitro method for the determination of drug diffusivity in the presence of mucin 

      Falavigna, Margherita; Stein, Paul C.; Flaten, Gøril Eide; Di Cagno, Massimiliano Pio (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-17)
      Mucosal drug delivery accounts for various administration routes (i.e., oral, vaginal, ocular, pulmonary, etc.) and offers a vast surface for the permeation of drugs. However, the mucus layer which shields and lubricates all mucosal tissues can compromise drugs from reaching the epithelial site, thus affecting their absorption and therapeutic effect. Therefore, the effect of the mucus layer on drug ...
    • Near-Infrared Fluorescent Imaging for Monitoring of Treatment Response in Endometrial Carcinoma Patient-Derived Xenograft Models 

      Fonnes, Tina; Strand, Elin; Fasmer, Kristine Eldevik; Berg, Hege Fredriksen; Espedal, Heidi; Sortland, Kristina; Stefansson, Ingunn; Bjørge, Line; Haldorsen, Ingfrid S; Krakstad, Camilla; McCormack, Emmet (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-06)
      Imaging of clinically relevant preclinical animal models is critical to the development of personalized therapeutic strategies for endometrial carcinoma. Although orthotopic patient-derived xenografts (PDXs) reflecting heterogeneous molecular subtypes are considered the most relevant preclinical models, their use in therapeutic development is limited by the lack of appropriate imaging modalities. ...
    • Glacial dynamics and fluid flow processes in Bjørnøyrenna and the Loppa High area, SW Barents Sea 

      Ødegård Garpestad, Tor Geir (Master thesis; Mastergradsoppgave, 2020-05-15)
      During the Late Weichselian glaciation, the Bjørnøyrenna ice stream was the main outlet of the Barents Sea Ice Sheet. In this thesis, a 3D seismic dataset from the Loppa High, located in the main ice stream trunk, has been used to study the glacial sediment package, revealing details on pastglacial dynamics, fluid flow processes and gas hydrate formation. Three seismic horizons have been interpreted: ...
    • Engineering geology of the Jettan rockslide, Kåfjorden 

      Berg, Jørgen Nicolai (Master thesis; Mastergradsoppgave, 2020-05-15)
      The unstable rock slope (URS) Jettan is located at Nordnesfjellet in Kåfjorden municipality in Troms and Finnmark County, 800 m above the fjord. The rockslide has an estimated volume of 6 Mm3, and moving at a rate of up to 50 mm a-1. Jettan is considered a “high risk object” within the Norwegian unstable mountain framework. This is due to the potential displacement wave impact to housings, infrastructure ...
    • The escherichia coli alkA gene is activated to alleviate mutagenesis by an oxidized deoxynucleoside 

      Grøsvik, Kristin; Tesfahun, Almaz Nigatu; Muruzábal-Lecumberri, Izaskun; Haugland, Gyri Teien; Leiros, Ingar; Ruoff, Peter; Kvaløy, Jan Terje; Knævelsrud, Ingeborg; Ånensen, Hilde; Alexeeva, Marina; Sato, Kousuke; Matsuda, Akira; Alseth, Ingrun; Klungland, Arne; Bjelland, Svein (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-25)
      The cellular methyl donor S-adenosylmethionine (SAM) and other endo/exogenous agents methylate DNA bases non-enzymatically into products interfering with replication and transcription. An important product is 3-methyladenine (m<sup>3</sup>A), which in <i>Escherichia coli</i> is removed by m<sup>3</sup>A-DNA glycosylase I (Tag) and II (AlkA). The <i>tag</i> gene is constitutively expressed, while ...
    • Isolation and Characterization of Antimicrobial Peptides with Unusual Disulfide Connectivity from the Colonial Ascidian Synoicum turgens 

      Hansen, Ida Kristine Østnes; Isaksson, Johan; Poth, Aaron G.; Østnes Hansen, Kine; Andersen, Aaron John Christian; Richard, Céline Sarah Marine; Blencke, Hans-Matti; Stensvåg, Klara; Craik, David J.; Haug, Tor (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-12)
      This study reports the isolation of two novel cysteine-rich antibacterial peptides, turgencin A and turgencin B, along with their oxidized derivatives, from the Arctic marine colonial ascidian <i>Synoicum turgens</i>. The peptides are post-translationally modified, containing six cysteines with an unusual disulfide connectivity of Cys<sup>1</i>-Cys<sup>6</sup>, Cys<sup>2</sup>-Cys<sup>5</sup>, and ...
    • Innovative methods to monitor rock and mountain slope deformation 

      Hormes, Anne; Adams, Marc; Amabile, Anna Sara; Blauensteiner, Franz; Demmler, Christian; Fey, Christine; Ostermann, Marc; Rechberger, Christina; Sausgruber, Thomas; Vecchiotti, Filippo; Vick, Louise Mary; Zangerl, Christian (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-02-17)
      Displacement rates of mountain slope deformations that can affect entire valley mountain flanks are often measured spatially distributed in‐situ without spatial significance. The spatially explicit measurement and recording of time series of slope deformations is a challenge, as the unstable slopes are often disintegrated into several subdomains, which move with different deformation rates. The ...
    • Energy efficiency of respiration in mature and newborn reindeer 

      Solberg, Simon Birger Byremo; Kjelstrup, Signe; Magnanelli, Elisa; Kizilova, Nataliya; Barroso, Iratxe Lorea Casado; Acquarone, Mario; Folkow, Lars (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-25)
      Reindeer (<i>Rangifer tarandus</i>) have evolved elaborate nasal turbinate structures that are perfused via a complex vascular network. These are subject to thermoregulatory control, shifting between heat conservation and dissipation, according to the animal’s needs. The three-dimensional design of the turbinate structures is essential in the sense that they determine the efficiency with which heat ...
    • Cytokine concentrations are related to level of mental distress in inpatients not using anti-inflammatory drugs 

      Toft, Helge Prytz; Lien, Lars; Neupane, Sudan Prasad; Abebe, Dawit Shawel; Tilden, Terje; Wampold, Bruce E.; Bramness, Jørgen G. (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-02)
      <p><i>Objective - </i>Cross-sectional data show elevated levels of circulating cytokines in psychiatric patients. The literature is divided concerning anti-inflammatory drugs’ ability to relieve symptoms, questioning a causal link between inflammatory pathways and psychiatric conditions. We hypothesised that the development of circulating cytokine levels is related to mental distress, and that this ...
    • Coronary heart disease and stroke in the Sami and non-Sami populations in rural Northern and Mid Norway - the SAMINOR Study 

      Siri, Susanna Ragnhild; Eliassen, Bent Martin; Broderstad, Ann Ragnhild; Melhus, Marita; Michalsen, Vilde Lehne; Jacobsen, Bjarne K.; Burchill, Luke; Braaten, Tonje (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-12)
      <i>Background</i> - Previous studies have suggested that Sami have a similar risk of myocardial infarction and a possible higher risk of stroke compared with non-Sami living in the same geographical area.<p><p> <i>Design</i> - Participants in the SAMINOR 1 Survey (2003–2004) aged 30 and 36–79 years were followed to the 31 December 2016 for observation of fatal or non-fatal events of acute ...
    • Modern Analogue Approach Applied to High-Resolution Varved Sediments - A Synthesis for Lake Montcortès (Central Pyrenees) 

      Vegas-Vilarrúbia, Teresa; Rull, Valentí; Trapote, Maria del Carmen; Cao, Min; Rosell-Melé, Antoni; Buchaca, Teresa; Gomà, Joan; López, Pilar; Sigró, Javier; Safont, Elisabet; Cañellas-Boltà, Núria; Garces Pastor, Sandra; Giralt, Santiago; Corella, Juan Pablo; Pérez-Zanón, Núria (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-02)
      In Quaternary paleosciences, the rationale behind analogical inference presupposes that former processes can be explained by causes operating now, although their intensity and rates can vary through time. In this paper we synthesised the results of different modern analogue studies performed in a varved lake. We discuss their potential value to obtain best results from high resolution past records. ...
    • Evidence for a direct harmful effect of alcohol on myocardial health: A large cross-sectional study of consumption patterns and cardiovascular disease risk biomarkers from northwest Russia, 2015 to 2017 

      Iakunchykova, Olena; Averina, Maria; Kudryavtsev, Alexander V; Wilsgaard, Tom; Soloviev, Andrey; Schirmer, Henrik; Cook, Sarah Anne; Leon, David Adrew (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-18)
      <i>Background</i> - Alcohol drinking is an increasingly recognized risk factor for cardiovascular disease. However, there are few studies of the impact of harmful and hazardous drinking on biomarkers of myocardial health. We conducted a study in Russia to investigate the impact of heavy drinking on biomarkers of cardiac damage and inflammation.<p><p> <i>Methods and Results</i> - The Know Your ...
    • Caring from the heart as belonging—The basis for mediating compassion 

      Hemberg, Jessica; Wiklund Gustin, Lena (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-10)
      <i>Aim</i> - The aim of this study was to illuminate nurses’ experiences of mediating compassion to patients in the home care context.<p><p> <i>Design</i> - A phenomenological–hermeneutical approach was used.<p><p> <i>Methods</i> - The data comprised of texts from interviews with 12 nurses in a home care context. Informed consent was sought from participants regarding participation in the ...
    • Fremtidens bygningsmaterialer 

      Gjerde, Klaus (Master thesis; Mastergradsoppgave, 2019-06-07)
      Bakgrunnen for oppgaven har vært å undersøke fremtidige bygningsmaterialer. Her er isolasjonsmaterialer og konstruksjonsmaterialer som betong, stål og massivtre gjennomgått. Det har i tillegg vært gjennomført et caseprosjekt hvor gjenbrukspotensialet for en bygning brukt i caseprosjektet har blitt vurdert. Videre ble livsløpsvurderinger for bygningen i caseprosjektet vurdert opp mot en tilsvarende ...
    • Early fulminant BK polyomavirus-associated nephropathy in two kidney transplant patients with low neutralizing antibody titers receiving allografts from the same donor 

      Lorentzen, Elias Myrvoll; Henriksen, Stian; Kaur, Amandeep; Kro, Grete Birkeland; Hammarström, Clara; Hirsch, Hans H; Midtvedt, Karsten; Rinaldo, Christine Hanssen (Journal article; Tidsskriftartikkel; Peer reviewed; Mastergradsoppgave; Master thesis, 2020-01-10)
      <i>Background</i> - BK Polyomavirus (BKPyV) causes premature graft failure in 1 to 15% of kidney transplant (KT) recipients. High-level BKPyV-viruria and BKPyV-DNAemia precede polyomavirus-associated nephropathy (PyVAN), and guide clinical management decisions. In most cases, BKPyV appears to come from the donor kidney, but data from biopsy-proven PyVAN cases are lacking. Here, we report the early ...
    • Transformation in manufacturer in the era of "Made in China 2025" 

      Li, Xuancheng (Master thesis; Mastergradsoppgave, 2019-06-07)
      China’s state council has unveiled a ten-year national plan, Made in China 2025, designed to transform China from a manufacturing giant into a world manufacturing power. Of all the projects includes in the “Made in China 2025” plan, intelligent and automated manufacturing is crucial. It is based on concepts i.e., internet of things, cloud computing, and big data. These technologies will be involved ...
    • Kontroll av FDVU-dokumentasjon og sammenheng med byggskader. Modell for kontroll av forvaltning-, drift-, og vedlikeholdsdokumentasjon i byggesaker, samt en vurdering av sammenheng mellom byggeskader og manglende eller ufullstendig FDVU-dokumentasjon 

      Alsen, Aleksander (Master thesis; Mastergradsoppgave, 2019-06-07)
      Missing or incomplete documentation for management, operation, and maintenance can become a problem in relation to both cost and quality. This thesis presents demands and responsible roles in given such documentation and uses the new standard SN/TS 3456:2018 Documentation for management, operations, maintenance and development (FDVU-documentation) to prepare a checklist/control-form for this ...
    • Rational selection of co-catalysts for the deaminative hydrogenation of amides 

      Artús Suàrez, Lluís; Jayarathne, Upul; Balcells, David; Bernskoetter, Wesley H.; Hazari, Nilay; Jaraiz, Martin; Nova, Ainara (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-20)
      The catalytic hydrogenation of amides is an atom economical method to synthesize amines. Previously, it was serendipitously discovered that the combination of a secondary amide co-catalyst with (<sup>iPr</sup>PNP)Fe(H)(CO) (<sup>iPr</sup>PNP = N[CH<sub>2</sub>CH<sub>2</sub>(P<sup>i</sup>Pr<sub>2</sub>)]<sub>2</sub>−), results in a highly active base metal system for deaminative amide hydrogenation. ...
    • «Det er et kjemperart system» – spesialpedagogikk, tilpasset opplæring og nyutdannede læreres kompetanse 

      Antonsen, Yngve; Maxwell, Gregor; Bjørndal, Kristin Emilie W; Jakhelln, Rachel Elise (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-05-13)
      De nye femårige grunnskolelærerutdanningene i Norge skal utdanne lærere med økt fag- og forskningskunnskap. Disse lærerne skal kunne tilpasse opplæringen til den enkelte elev og integrere spesialundervisning i grunnskolen. Studiens forskningsspørsmål er: Hvordan erfarer nyutdannede grunnskolelærere at den formelle lærerkompetansen fra en integrert femårig grunnskolelærerutdanning samsvarer med deres ...