Short histidine-rich peptides could serve as novel activatable vectors for delivering cytotoxic payloads to tumor and neovasculature cells. This explorative study reports preliminary results showing that zinc ions, which are found in elevated levels at neovasculature sites, can trigger the intracellular delivery of a short antimicrobial peptide when conjugated to a histidine-rich peptide through a ...

The terrestrial Arctic is warming rapidly, causing changes in the degree of freezing of the upper sediments, which the mechanical properties of unconsolidated sediments strongly depend upon. This study investigates the potential of using time-lapse surface seismics to monitor thawing of currently (partly) frozen ground utilizing synthetic and real seismic data. First, we construct a simple geological ...

Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune response associated with immunological memory, provided they display sufficient antigenicity and adjuvanticity. Moreover, multiple intracellular and microenvironmental features determine the propensity of RCD to drive adaptive immunity. Here, we provide an updated operational definition of immunogenic cell death ...

<p><i>Introduction - </i>Access to healthcare services for legal immigrants in Scandinavia is part of the policy agenda of the various governments as they strive to provide equal healthcare services to its citizens. Legal immigrants have the same rights as natives; however, studies have shown that there are inequalities in access to healthcare services between legal immigrants and natives. The extent ...

Henrik Steffens’ erste wissenschaftliche Buchpublikation, Udkast til en Lærebog i Botaniken (1794), war die Übersetzung eines botanischen Klassikers des ausgehenden 18. und frühen 19. Jahrhunderts, Carl Ludwig Willdenows Grundriss der Kräuterkunde (1792). Der vorliegende Beitrag arbeitet anhand dieser bislang wenig beachteten Übersetzung Steffens’ Position als Naturwissenschaftler im Übergang von ...

I denne artikkelen gjør jeg en nylesing av Marianne Gullestads bok <i>Hverdagsfilosofer. Verdier, selvforståelse og samfunnssyn i det moderne Norge</i>, med særlig vekt på hennes fortolkning av sjøsamiske Einars selvbiografi – og måter Einar reflekterer rundt minner og felles hukommelse gjennom landskap. For å kunne utdype argumentasjon om minner som del av et landskap, vil jeg sette Gullestads ...

The Karasjok Greenstone Belt (KGB) is a N-S trending supracrustal belt in Northern Norway. The KGB may comprise economically important mineral resources. Thus, a better understanding of ore genesis and structural architecture is key information for future exploration. The purpose of this master thesis is to perform detailed structural analysis based on field work in the northern part of KGB. Field ...

MicroRNAs (miRNAs) are non-coding RNAs that execute their function by targeted downregulation of gene expressions. There is growing evidence from epidemiological studies and animal models suggesting that the expression level of miRNAs is dysregulated in venous thromboembolism (VTE). In this review, we summarize the current knowledge on the role of miRNAs as biomarkers for VTE and provide general ...

The seasonal dynamic of lipids and their fatty acid constituents in the lipid sac and muscles of pelagic postlarval <i>Leptoclinus maculatus</i>, an ecologically important fish species in the Arctic food nets, in Kongsfjord, Svalbard waters was studied. The determination of the qualitative and quantitative content of the total lipids (TLs), total phospholipids (PLs), triacylglycerols (TAGs), cholesterol ...

<i>Background</i> - The International Commission on Radiological Protection’s (ICRP) justification principles state that an examination is justified if the potential benefit outweighs the risk for radiation harm. Computer tomography (CT) contributes 50% of the radiation dose from medical imaging, and in trauma patients, the use of standardized whole body CT (SWBCT) increases. Guidelines are lacking, ...