<i>Objectives</i> - To evaluate critical care nurses’ experiences of ICU diaries following the implementation of national recommendations for the use of diaries for critically ill patients.<p><p> <i>Design</i> - A quality improvement project describing the development and implementation of national recommendations (2011), as well as the assessment of the use of diaries in intensive care nursing ...

<i>Background</i> - Treatment of arrhythmias evoked by accidental or therapeutic hypothermia and rewarming remains challenging. We aim to find an ECG-biomarker that can predict ventricular arrhythmias at temperatures occurring in therapeutic and accidental hypothermia.<p><p> <i>Main body</i> - Evaluation of ECG-data from accidental and therapeutic hypothermia patients and experimental data on ECG ...

Formålet med denne utredningen er å øke forståelsen for reaksjonen til den endringsvante militært ansatte i Forsvaret. Utredningen er en singelcase studie av en hæravdeling Forsvaret. Metodisk tilnærming i oppgaven er kvalitative intervjuer, dataen til analysen presenteres og drøftes i samme kapittel. Samtlige intervju er transkribert samt at relevante funn har blitt analysert og tolket opp mot ...

Background: Mass spectrometry-based proteomics has increasingly been the choice of method for the global analysis of the composition, modification and dynamics of proteins. Quantitative analysis of the proteome with tandem mass tag is a technique for calculating the relative abundance of the proteome in tissues and organelles. In this thesis, present a novel bottom-up method for the quantitative ...

Neuroblastoma is the most common diagnosed tumor in infants and the second most common extracranial tumor of childhood. The survival rate of patients with high-risk neuroblastoma is still very low despite intensive multimodal treatments. Therefore, new treatment strategies are needed. In recent years, miRNA-based anticancer therapy has received growing attention. Advances in this novel treatment ...

Abnormal increases in nucleolar size and number caused by dysregulation of ribosome biogenesis has emerged as a hallmark in the majority of spontaneous cancers. The observed ribosome hyperactivity can be directly induced by the MYC transcription factors controlling the expression of RNA and protein components of the ribosome. Neuroblastoma, a highly malignant childhood tumor of the sympathetic nervous ...

Fish or crustaceans stuck in the fishing gear meshes can lead to operational problems in some fisheries and thereby affect the economic gain. However, mesh sticking probability has never been formally quantified as a part of the estimation of fishing gear size selectivity. Therefore, this study developed a size selection model and estimation procedure that, besides the size dependent retention and ...

This study reports the isolation of two novel cysteine-rich antibacterial peptides, turgencin A and turgencin B, along with their oxidized derivatives, from the Arctic marine colonial ascidian <i>Synoicum turgens</i>. The peptides are post-translationally modified, containing six cysteines with an unusual disulfide connectivity of Cys¹-Cys⁶, Cys²-Cys⁵, and ...

Den matematiske samtalen i tradisjonelle og virtuelle klasserom er en kvalitativ studie hvor vi ser på lærernes bruk av samtaletrekk som redskap for å skape ei aktiv tilnærming til matematikkfaget i de to ulike klasseromsformene. Det teoretiske fundamentet for studien og datainnsamlingen tar utgangspunkt i Chapin et al. (2009) sine samtaletrekk (gjenta, repetere, resonnere, tilføye, vente, snu ...

Multidrug-resistant (MDR) bacteria, including Escherichia coli, producing extended-spectrum β-lactamase (ESBL), AmpC or carbapenemases, are acknowledged among the most significant global health threats. Growing rates of MDR E.coli can lead to an increase in the use of reserve antimicrobials. Re-introducing “old antimicrobials” could offer a timely solution. This work aimed at evaluating the role of ...