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The crystal structure of haemoglobin from Atlantic cod
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-16)The crystal structure of haemoglobin from Atlantic cod has been solved to 2.54 A˚ resolution. The structure consists of two tetramers in the crystallographic asymmetric unit. The structure of haemoglobin obtained from one individual cod suggests polymorphism in the tetrameric assembly. -
Development of a Framework for the Investigation of Speed, Power and Kinematic Patterns in Para Cross-Country Sit-Skiing: A Case Study of an LW12 Athlete
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-31)<i>Objective</i>: To develop a framework for the investigation of speed, power, and kinematic patterns across varying terrain in cross-country (XC) sit-skiing, and to test this framework in a XC sit-skier of the LW12 class during high- (HIT) and low-intensity (LIT) endurance training.<p> <p><i>Methods</i>: One XC sit-skiing athlete of the LW12 class with a single above-the-knee amputation was ... -
The retropubic tension-free vaginal tape procedure—Efficacy, risk factors for recurrence and long-term safety
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-14)<i>Introduction</i> - The retropubic tension‐free vaginal tape has been the preferred method for primary surgical treatment of stress urinary incontinence and stress‐dominated mixed urinary incontinence in women for more than 20 years. This study presents long‐term safety and efficacy data and assesses risk factors for long‐term recurrence.<p> <p><i>Material and methods</i> - In a case‐series ... -
Lessons learned from accident and near-accident experiences in traffic
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-08-17)The focus of this article is risky behavior in traffic. What do people learn from accidents and near-accidents? Experience with accidents may demand increased caution. However, near-accidents are inherently ambiguous: On the one hand, they signal that margins were good enough, inspiring increased risk-taking; on the other hand, they signal danger that could induce increased caution. To explore these ... -
Challenging the ethnic pyramid: Golden rules and organisational measures towards a more inclusive work environment
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-25)<i>Aim</i> - To contribute to knowledge of how healthcare managers can promote connection and ethnic equality among staff in multicultural organisations.<p> <p><i>Background</i> - The increase in migrant care workers often leads to deskilling, discrimination, communication difficulties and harsh working conditions.<p> <p><i>Methods</i> - A constructivist grounded theory approach was used ... -
Filtered beauty in Oslo and Tokyo: A spatial frequency analysis of facial attractiveness
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-14)Images of European female and male faces were digitally processed to generate spatial frequency (SF) filtered images containing only a narrow band of visual information within the Fourier spectrum. The original unfiltered images and four SF filtered images (low, medium-low, medium-high and high) were then paired in trials that kept constant SF band and face gender and participants made a forced-choice ... -
Absorptive capacity and energy efficiency in manufacturing firms – An empirical analysis in Norway
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-02)Increased energy efficiency (EE) in manufacturing firms is important for confronting climate challenges. However, the information barrier is considered a major restriction on EE innovation. Building on the theory of absorptive capacity and the current EE literature, we argue that this barrier relates to firms' ability to assimilate and exploit information. Thus, this study's objective is to analyse ... -
Responses to positive and aversive stimuli in estrous female rats housed in a seminatural environment: Effects of yohimbine and chlordiazepoxide
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-05)The behavioral effects of putative anxiolytic and anxiogenic drugs are usually evaluated in highly standardized tests. Here, we determined the effects of such drugs in rats housed in mixed sex groups in a seminatural environment. Sexually receptive female Wistar rats were treated with either the anxiolytic drug chlordiazepoxide (2 mg/kg), the anxiogenic drug yohimbine (1 mg/kg), or saline (1 ml/kg). ... -
Matrix metalloproteinase-9 mediated shedding of syndecan-4 in glomerular endothelial cells
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-31)<p><i>Background - </i>Diabetic nephropathy is the most common cause of end‐stage renal failure in the western world and Asia. The mechanisms are not fully elucidated, but disruption of glomerular endothelial glycocalyx and shedding of its components including syndecans has been implicated. <p><i>Aims - </i>We hypothesize that reduced glomerular filtration in diabetes is caused by disruption of ... -
Patterns of treatment and outcome in patients with 20 or more brain metastases
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01)<p><i>Background/Aim - </i>The aim of this study was to analyze the patterns of treatment and outcomes in patients with a large number of brain metastases, arbitrarily defined as 20 or more lesions. These patients are typically excluded from studies of focal brain treatment, e.g., surgery or radiosurgery, and might have a limited prognosis. <p><i>Patients and Methods - </i>This was a retrospective ... -
Injuries in Swedish floorball players: A nationwide matched cohort study.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-07)The aim of this study was to investigate injury incidence and patterns in female and male floorball players of different ages compared with matched controls. This study involved all floorball players in Sweden and licensed during 2010–2012, and matched controls selected from Sweden’s Total Population Register. Injury diagnoses were acquired from national health care registers. The cohort comprised ... -
Dietary patterns of adults and their associations with Sami ethnicity, sociodemographic factors, and lifestyle factors in a rural multiethnic population of northern Norway - the SAMINOR 2 clinical survey
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-04)<i>Background</i> - Few population-based studies have assessed dietary behaviors in the rural multiethnic population of Northern Norway. The present study determined dietary patterns and investigated their association with Sami ethnicity, sociodemographic factors, and lifestyle factors in a multiethnic population in rural Northern Norway.<p> <p><i>Methods</i> - This cross-sectional study ... -
Mucosal Metabolomic Profiling and Pathway Analysis Reveal the Metabolic Signature of Ulcerative Colitis
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-11-27)The onset of ulcerative colitis (UC) is characterized by a dysregulated mucosal immune response triggered by several genetic and environmental factors in the context of host–microbe interaction. This complexity makes UC ideal for metabolomic studies to unravel the disease pathobiology and to improve the patient stratification strategies. This study aims to explore the mucosal metabolomic profile in ... -
MiRNAs‐181a/b therapy in lung cancer: reality or myth?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-03)Despite substantial progress in oncology, lung cancer remains the number one malignancy in terms of both incidence and mortality rates, and there thus remains an urgent need for new therapeutic alternatives. MicroRNA (miRNA) have an important role in cancer initiation and progression due to their capacity to interfere with transcriptional signaling and regulate key cellular processes. miR‐181a and ... -
Use of skincare products and risk of cancer of the breast and endometrium: a prospective cohort study
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-03)<i>Background</i> - Concerns have been raised that extensive use of personal care products that contain endocrine disrupting compounds increase the risk of hormone sensitive cancers.<p> <p><i>Objective</i> - To assess the effect of skincare product use on the risk of pre- and postmenopausal breast cancer, estrogen receptor positive (ER+) and negative (ER-) breast cancer and cancer of the ... -
Gengangere var i virkeligheden en bestseller
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-05-09)Henrik Ibsens <i>Gengangere</i> fik en barsk modtagelse i pressen, da skuespillet udkom i december 1881. I dag bliver det gerne brugt som eksempel på samtidens manglende forståelse for forfatteren, og bogen bliver beskrevet som en salgsfiasko og anses som en af undtagelserne i Ibsens ellers så populære forfatterskab. Denne artikel argumenterer for, at litteraturhistoriens og receptionshistoriens ... -
Two interventions to treat pain disorders and post-traumatic symptoms among Syrian refugees: protocol for a randomized controlled trial
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-12-27)<i>Background</i> - There is a high prevalence of pain and post-traumatic symptoms among refugees and feasible interventions to manage these are needed. However, knowledge about the effect of physiotherapy and psychological group interventions among refugees is scarce. Our aim is to determine whether two different interventions, the Physiotherapy Activity and Awareness Intervention (PAAI) and ... -
Genetic relationships of European, Mediterranean, and SW Asian populations using a panel of 55 AISNPs
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-07-08)The set of 55 ancestry informative SNPs (AISNPs) originally developed by the Kidd Lab has been studied on a large number of populations and continues to be applied to new population samples. The existing reference database of population samples allows the relationships of new population samples to be inferred on a global level. Analyses show that these autosomal markers constitute one of the better ... -
Reduced methane seepage from Arctic sediments during cold bottom-water conditions
(Journal article; Tidsskriftartikkel; Peer reviewed, 2020-01-13)Large amounts of methane are trapped within gas hydrate in subseabed sediments in the Arctic Ocean, and bottom-water warming may induce the release of methane from the seafloor. Yet the effect of seasonal temperature variations on methane seepage activity remains unknown as surveys in Arctic seas are conducted mainly in summer. Here we compare the activity of cold seeps along the gas hydrate stability ... -
Updating verbal fluency analysis for the 21st century: Applications for psychiatry
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-02-07)Evaluating patients’ verbal fluency by counting the number of unique words (e.g., animals) produced in a short-period (e.g., 1–3 min) is one of the most widely employed cognitive tests in psychiatric research. We introduce new methods to analyze fluency output that leverage modern computational language technology. This enables moving beyond simple word counts to charting the temporal dynamics of ...