Munin: Nye registreringer
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Respiratory morbidity and therapy in very preterm infants – a population-based study from 2009-2018
(Master thesis; Mastergradsoppgave, 2022-05-24)<p>Introduction: The association between respiratory support and lung disease is known. This study analysed the duration of different respiratory managements for preterm infants born before week 28 and between week 28-31 and preterm infants with BPD. Regional differences were also evaluated. <p>Materials and methods: a nationwide population-based registry study, and the data is gathered from ... -
Risk Assessment of a Mars Colony Utilizing a Mars-Svalbard Training Analog
(Master thesis; Mastergradsoppgave, 2024-05-04)As the space industry is rapidly privatized and countries once again have their eyes set on the moon and beyond, humanity is getting closer and closer to the days where a colony on Mars is a reality. During the preliminary planning phase of a mission to Mars, a large scale, top-down overview is essential. This report applies a risk and safety engineering approach to identify each of the core hazards, ... -
Towards Developing a Global Policy Framework to Regulate Big Tech’s Impact on Democracy: A Global South Perspective
(Master thesis; Mastergradsoppgave, 2023-05-22)Technology and innovations have been rapidly evolving and infiltrating almost every aspect of human lives. These innovations have allowed humanity to excel in unprecedented manners. State, market, and culture form the basis of a society, and Big Tech companies have now captured all. Through online surveillance, political advertising online, and algorithmic targeting, there have been serious implications ... -
Hvilken rolle spiller en observasjonspost på et sykehus? En studie av innleggelser på observasjonsposten ved Nordlandssykehuset Bodø 2016-2021
(Master thesis; Mastergradsoppgave, 2022-05-27)Sammendrag Tittel: Hvilken rolle spiller en observasjonspost på et sykehus? En studie av innleggelser på observasjonsposten ved Nordlandssykehuset Bodø 2016-2021 Formål: Denne oppgaven har som formål å kartlegge pasientpopulasjonen som har blitt behandlet på observasjonsposten gjennom virksomhetsregistrering gjort i DIPS Arena. Oppgaven har også som formål å kartlegge DRG-produksjonen til ... -
Etterretningstjenestens adgang til å foreta tilrettelagt innhenting - Reglene om tilrettelagt innhenting etter forslag til ny lov om Etterretningstjenesten, i lys av EMK artikkel 8
(Mastergradsoppgave; Master thesis, 2019-05-27)Tema for avhandlingen er hvorvidt Etterretningstjenestens foreslåtte adgang til å benytte overvåkningsmetoden "tilrettelagt innhenting", er i tråd med de menneskerettslige kravene etter Den europeiske menneskerettighetskonvensjonen (EMK) artikkel 8. -
Sekundærprofylakse etter perkutan koronar intervensjon ved Nordlandssykehuset
(Master thesis; Mastergradsoppgave, 2022-05-26)Bakgrunn: Hjerte- og karsykdom er en ledende årsak til morbiditet og mortalitet på verdensbasis. Selv om det har vært en signifikant bedring i behandlingen de siste tiårene, har behandling på lengre sikt vist seg å være utfordrende. Morbiditeten etter akutt koronarsyndrom har vist seg å være høy, hvor en stor andel opplever nye kardiovaskulære hendelser i løpet av de to første årene. I dag foreligger ... -
Moving sperm forward
(Mastergradsoppgave; Master thesis, 2023-05-26)Objective: The purpose of this study was to investigate a manual sperm sorting method (Swim-up) and a non-invasive microfluidics method (Zymot microfluidics) with emphasis on formation of reactive oxygen species (ROS) and DNA fragmentation as objective measurements of spermatozoa quality. Standard phase contrast imaging of spermatozoa was compared with quantitative phase contrast microscopy (QPM) ... -
CT-veiledet lungebiopsi ved radiologisk avdeling UNN: Komplikasjonsfrekvens og risikofaktorer for komplikasjoner. En retrospektiv kvalitetsstudie.
(Master thesis; Mastergradsoppgave, 2022-05-25)Objektiv: Dette er en retrospektiv kvalitetsstudie med formål å undersøke komplikasjonsfrekvens og risikofaktorer for komplikasjoner ved CT-veiledet lungebiopsi utført ved UNN Tromsø. Vi har også undersøkt diagnostisk treffsikkerhet ved prosedyren. Materiale og metode: Alle pasienter som hadde fått utført CT-veiledet lungebiopsi ved radiologisk avdeling, UNN Tromsø i løpet av perioden 17/11/2020 ... -
Characterization of extracellular vesicles from U-2OS15E, a human osteosarcoma cell line persistently infected by BK polyomavirus
(Mastergradsoppgave; Master thesis, 2021-05-25)The human polyomavirus BKPyV infects most people worldwide and establishes a lifelong persistent infection in the renourinary tract. The virus rarely gives symptoms in healthy people, but it can cause severe disease under certain immunocompromised states. Despite its high prevalence, our knowledge about how the virus evades host immunity and persists still poor. Extracellular vesicles (EVs) ... -
How does the number of previous operations affect patient-rated outcome after surgery for lumbar spinal stenosis or lumbar disc herniation? A population-based cohort study from the Norwegian Registry for Spine Surgery
(Master thesis; Mastergradsoppgave, 2021-05-25)Background: Several small, mainly single centre studies have linked repeated operations to inferior outcomes compared to primary operations after lumbar spine surgery. Few studies have specifically quantified the influence of previous operations on the outcome. Objectives: The aim of the study was to examine whether, and if so, to which extent the number of previous operations is associated with ... -
Life on Air: On the Physiological Basis of Atmospheric Methane Oxidizing Bacteria
(Doctoral thesis; Doktorgradsavhandling, 2024-06-11)Atmospheric methane oxidizing bacteria (atmMOB) are the only known organisms that can consume methane (CH<sub>4</sub>) directly from the air. Therefore, they are referred to as biological CH<sub>4</sub> sink. CH<sub>4</sub> is a potent greenhouse gas, and its increasing atmospheric concentration accelerates global warming. By consuming the CH<sub>4</sub> from the air, atmMOB mitigate global warming. ... -
Engineering novel bacterial biosensors for the characterization of membrane active natural products
(Doctoral thesis; Doktorgradsavhandling, 2024-06-10)<p>Treatment of bacterial infections has become more challenging due to the expansion of antibiotic resistance. Especially, resistant Gram-negative pathogens are burdening healthcare systems worldwide. This increases the need for new antibiotics able to penetrate the outer-membrane (OM) of Gram-negatives. Natural products (NPs) from the marine environment e.g. antimicrobial peptides (AMPs) are ... -
How Religion and Spirituality Impact Mental Health and Mental Help-Seeking Behavior in Arctic Norway: an Epidemiological Study Adopting the SAMINOR 2 Questionnaire Survey
(Doctoral thesis; Doktorgradsavhandling, 2024-06-07)<p><i>Objectives:</i> Most international studies have shown that religion and spirituality (R/S) are related to better mental health, yet the Indigenous Sámi—being more committed to R/S than the majority population in the area—have poorer mental health and are more inclined toward suicidal behavior. Laestadianism—an important R/S factor for these people and this region—is related to poorer mental ... -
Real-time feedback on chest compression efficacy by hands-free carotid Doppler in a porcine model
(Journal article; Tidsskriftartikkel, 2024-02-20)Aim: Current guidelines for cardiopulmonary resuscitation (CPR) recommend a one-size-fits-all approach in relation to the positioning of chest compressions. We recently developed RescueDoppler, a hands-free Doppler ultrasound device for continuous monitoring of carotid blood flow velocity during CPR. The aim of the present study is to investigate whether RescueDoppler via real-time hemodynamic ... -
Absorption and pharmacokinetics of bupivacaine after bilateral topical administration in tonsillar fossae for posttonsillectomy pain relief
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-04-10)No previous studies have investigated the systemic absorption of bupivacaine when used topically for posttonsillectomy pain. The present study was undertaken to investigate the pharmacokinetics of bupivacaine after administration by a swab in the tonsillar fossae over 4 min after tonsillectomy. Eleven adult patients undergoing elective tonsillectomy were recruited. After removal of both tonsils, ... -
Femoral Nailing in a Porcine Model Causes Bone Marrow Emboli in the Lungs and Systemic Emboli in the Heart and Brain
(Journal article; Tidsskriftartikkel; Peer reviewed, 2024-02-28)Background: Shaft fractures of the femur are commonly treated with intramedullary nailing, which can release bone marrow emboli into the bloodstream. Emboli can travel to the lungs, impairing gas exchange and causing inflammation. Occasionally, emboli traverse from the pulmonary to the systemic circulation, hindering perfusion and resulting in injuries such as heart and brain infarctions, known ... -
Tredjepartsvirkninger av åpenhetsloven
(Mastergradsoppgave; Master thesis, 2023-05-24)Siktemålet med avhandlingen er å kartlegge hvilke rettslige mekanismer virksomheten som omfattes av åpenhetsloven kan bruke for å sikre seg overfor deres medkontrahenter som ikke omfattes av åpenhetsloven. -
Sammenhengen mellom fysisk aktivitet, troponin, NT-proBNP og atrieflimmer. En tverrsnittsundersøkelse av en kohort i Tromsøundersøkelsen (Tromsø 7, 2015-2016)
(Master thesis; Mastergradsoppgave, 2022-05-24)Forekomsten av atrieflimmer er høyere hos utholdenhetsutøvere sammenlignet med ikke-utholdenhetsutøvere. Samtidig er det sett økt utslipp av proBNP og troponin ved utholdenhetstrening. Dette er interessant sett i lys av studier som indikerer økte nivåer av disse hjertemarkørene hos individer med atrieflimmer, og studier som indikerer at hjertemarkørene kan være med å predikere risiko for atrieflimmer. ... -
Antimicrobial activities and mechanisms of action of peptide analogues of marine origin
(Doctoral thesis; Doktorgradsavhandling, 2024-06-06)<p>Modern medicine is threatened by the emergence of antimicrobial resistance (AMR). New agents with unique structures and mechanisms of action are urgently needed to address the problems associated with AMR. To effectively address this challenge, a proper understanding of the structure-activity relationship is required to decipher the mechanism of action of novel compounds. Template-based design ... -
Towards personalized medicine in ulcerative colitis. Long-term follow-up after biological treatment and prediction of clinical outcomes
(Doctoral thesis; Doktorgradsavhandling, 2024-06-20)Ulcerøs kolitt (UC) er en kronisk tarmsykdom kjennetegnet med betennelse i tykktarmen som forårsaker symptomer som magesmerter, blodig avføring og diaré. Å forstå årsakene til UC er utfordrende og involverer en kompleks blanding av faktorer som immunsystemproblemer, eksponering for mikrober og genetiske påvirkninger. Et gjennombrudd i UC-behandling kom med anti-tumor nekrose faktor (anti-TNF) ...