Viser treff 6441-6460 av 36350

    • AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research 

      Olsvik, Hallvard Lauritz; Johansen, Terje (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-08)
      Proteins are structural and executing macromolecules essential for life in all biological systems. Insight into proteins structures is required for detailed mechanistic understanding of how they work and solve different tasks. The ability to predict three-dimensional (3D) protein structures from primary sequence information has therefore been an open research question for more than 50 years. The ...
    • Cohort profile: The Clinical and Multi-omic (CAMO) cohort, part of the Norwegian Women and Cancer (NOWAC) study 

      Delgado, André Berli; Tylden, Eline Sol Garthsdatter; Lukic, Marko; Moi, Line Haugan; Rasmussen Busund, Lill-Tove; Lund, Eiliv; Olsen, Karina Standahl (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-06)
      Introduction - Breast cancer is the most common cancer worldwide and the leading cause of cancer related deaths among women. The high incidence and mortality of breast cancer calls for improved prevention, diagnostics, and treatment, including identification of new prognostic and predictive biomarkers for use in precision medicine.<p> <p>Material and methods - With the aim of compiling a cohort ...
    • Can policies improve language vitality? The Sámi languages in Sweden and Norway 

      Lloyd-Smith, Anika; Bergmann, Fabian; Hund, Laura; Kupisch, Tanja (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-29)
      Introduction: Language policies are often aimed at changing language behaviours, yet it is notoriously difficult to assess their effects. This study investigates language use and competence in the Indigenous Sámi populations of Norway and Sweden in light of the national-level policies the two countries have adopted.<p> <p>Methods: We provide a cross-country comparison of relevant educational, ...
    • Enhancing questioning skills through child avatar chatbot training with feedback 

      Røed, Ragnhild Klingenberg; Baugerud, Gunn Astrid; Zohaib Hassan, Syed; Shafiee Sabet, Saeed; Salehi, Pegah; Powell, Martine B.; Riegler, Michael Alexander; Halvorsen, Pål; Sinkerud Johnson, Miriam (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-13)
      Training child investigative interviewing skills is a specialized task. Those being trained need opportunities to practice their skills in realistic settings and receive immediate feedback. A key step in ensuring the availability of such opportunities is to develop a dynamic, conversational avatar, using artificial intelligence (AI) technology that can provide implicit and explicit feedback to ...
    • En trøstende kontakt mellom sykepleier og pasient 

      Glad, Tone (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-30)
      Hensikten med dette essay er å belyse hva trøst i sykepleien kan være og hvordan kontakt mellom pasient og sykepleier kan oppleves trøstende for pasienter. Bakgrunnen for essayet er en pasients brev til sykepleier om det å ha noen å snakke med under behandlingsoppholdet i sykehuset. I samtalen med pasienten kan sykepleier oppnå kontakt, også kontakt med sin egen karakter og grenser. Når vi tror ...
    • 'In-' como operador escalar y su comportamiento adjetival 

      Fábregas, Antonio (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-01-11)
      En la bibliografía se ha señalado repetidamente la asociación del prefijo in-, habitualmente clasificado como ‘negativo’, y la categoría de los adjetivos. Son frecuentes los casos citados en la bibliografía en los que el prefijo facilita que una voz de categoría verbal deba ser interpretada como adjetivo (opinado ~ inopinado), así como algunos casos en que el prefijo convierte un sustantivo ...
    • C-reactive protein levels and depression in older and younger adults - A study of 19,947 individuals. The Tromsø study 

      Bugge, Erlend; Wynn, Rolf; Mollnes, Tom Eirik; Reitan, Solveig Merete Klæbo; Lapid, Maria I.; Grønli, Ole Kristian (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-17)
      In recent years, a connection between depression and inflammation has been established, with a range of immunological changes, both cellular and humoral, presenting during depressive states (Beydoun et al., 2016; Haapakoski et al., 2015; Wium-Andersen et al., 2013). Furthermore, there seems to be a dose-response relationship between depression and inflammation, in the sense that the more severe the ...
    • 13-Type HPV DNA Test versus 5-Type HPV mRNA Test in Triage of Women Aged 25–33 Years with Minor Cytological Abnormalities–6 Years of Follow-Up 

      Rad, Amir; Sørbye, Sveinung; Brenn, Tormod; Tiwari, Sweta; Løchen, Maja-Lisa; Skjeldestad, Finn Egil (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-25)
      Background: A specific, cost-effective triage test for minor cytological abnormalities is essential for cervical cancer screening among younger women to reduce overmanagement and unnecessary healthcare utilization. We compared the triage performance of one 13-type human papillomavirus (HPV) DNA test and one 5-type HPV mRNA test. Methods: We included 4115 women aged 25–33 years with a screening ...
    • Exploring the use of technology designed to support the supervision process in teacher training placements. 

      Bjørndal, Cato R. P.; Mathisen, Petter; Wennergren, Ann-Christine; Thornberg, Fredrik (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-14)
      The practicum supervision process in teacher education comprises various cyclic experiential learning activities (e.g. planning, observation and supervision conversation). Research has documented considerable challenges relating to this process, but also that digital technology can help. In the study, a software program designed for practicum supervision (MOSO) is tested in three Scandinavian ...
    • Safety and effectiveness of monovalent COVID-19 mRNA vaccination and risk factors for hospitalisation caused by the omicron variant in 0.8 million adolescents: A nationwide cohort study in Sweden 

      Nordström, Peter; Ballin, Marcel; Nordstrom, Anna Hava (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-21)
      Background<p> <p>Real-world evidence on the safety and effectiveness of Coronavirus Disease 2019 (COVID-19) vaccination against severe disease caused by the omicron variant among adolescents is sparse. In addition, evidence on risk factors for severe COVID-19 disease, and whether vaccination is similarly effective in such risk groups, is unclear. The aim of the present study was therefore to examine ...
    • A technique for volumetric incoherent scatter radar analysis 

      Stamm, Johann Immanuel; Vierinen, Juha; Gustavsson, Bjorn Johan; Spicher, Andres (Journal article; Tidsskriftartikkel, 2023-01-19)
      Volumetric measurements of the ionosphere are important for investigating spatial variations of ionospheric features, like auroral arcs and energy deposition in the ionosphere. In addition, such measurements make it possible to distinguish between variations in space and time. While spatial variations in scalar quantities such as electron density or temperature have been investigated with incoherent ...
    • Management’s Discretionary Assessments of Goodwill Impairments—Evidence from STOXX Europe 600 

      Kjærland, Frode; Forbord, Kristian; Oust, Are; Stephani, Håkon (Journal article; Tidsskriftartikkel, 2023-06-20)
      The main issues of accounting reporting regarding goodwill are whether a firm’s management reliably conveys their private information about future earnings, and whether they disclose value-relevant and useful information to accounting users. In the current International Financial Reporting Standards (IFRS) regulations, the goodwill impairment test is based on management’s discretionary assessments. ...
    • Earlier sea-ice melt extends the oligotrophic summer period in the Barents Sea with low algal biomass and associated low vertical flux 

      Kohlbach, Doreen; Goraguer, Lucie; Bodur, Yasemin V.; Müller, Oliver; Amargant Arumí, Martí; Blix, Katalin; Bratbak, Gunnar; Chierici, Melissa; Dabrowska, Anna Maria; Dietrich, Ulrike; Edvardsen, Bente; Garcia, Laura; Gradinger, Rolf Rudolf; Hop, Haakon; Jones, Elizabeth Marie; Øyvind, Lundesgaard; Olsen, Lasse Mork; Reigstad, Marit; Saubrekka, Karoline; Tatarek, Agnieszka; Wiktor, Josef Maria; Wold, Anette; Assmy, Philipp (Journal article; Tidsskriftartikkel, 2023-03-27)
      The decrease in Arctic sea-ice extent and thickness as a result of global warming will impact the timing, duration, magnitude and composition of phytoplankton production with cascading effects on Arctic marine food-webs and biogeochemical cycles. Here, we elucidate the environmental drivers shaping the composition, abundance, biomass, trophic state and vertical flux of protists (unicellular eukaryotes), ...
    • Marine Genetic Resources in Areas Beyond National Jurisdiction: Developing States and issues related to equitable benefit sharing 

      Nikolaisen, Ingrid (Master thesis; Mastergradsoppgave, 2022-08-31)
      One of the “2011 package” issues brought to light through the BBNJ negotiation is the question of benefit sharing. In that context, this thesis aims to consider which measures are necessary to ensure fair and equal access and utilization of the benefits derived from MGR activities in ABNJ. The research will examine the previous negotiations to identify the range of potential measures that ...
    • Bruk av glukokortikoider i oral medisin 

      Aaøyen, Øyvind; Johansen, Hanna P.; Dragland, Lars Roger (Master thesis; Mastergradsoppgave, 2023-05-02)
      Denne masteroppgaven tar for seg konsensus i bruk av glukokortikoider blant norske spesialister, retningslinjer og hva som finnes i litteraturen. Videre ønsker vi å sammenligne behandling av oraleslimhinne lidelser med glukokortikoider og ikke-steroidholdige alternativer. Metoden som ble brukt i denne undersøkelsen var en spørreundersøkelse sendt til spesialistene i Norge som oftest har konsultasjoner ...
    • Dental implant treatment in irradiated oral cancer patients. Clinical routines in Norway and a review of the literature 

      Jensen, Amalie Storaa; Hestnes, Ida Johansen (Master thesis; Mastergradsoppgave, 2023-04-28)
      The study seeks to find out if there is a difference in prognosis of primary and secondary dental implantation, i.e. before or after radiotherapy respectively, in cancer patients. We carried out a literature search, as well as investigating if there were different practices at the various hospitals in Norway who perform such treatment.
    • BRICS and the West: Don’t Believe the Cold War Hype 

      Coning, Cedric Hattingh de (Chronicle; Kronikk, 2023-08-30)
      When Jim O’Neill coined the BRIC acronym in 2001, the point he was trying to convey was that the global economic system needed to incorporate the world’s largest emerging economies. His advice fell on deaf ears and in 2009, Brazil, China, India, and Russia decided to take matters into their own hands and formed the BRIC grouping. South Africa joined the group in 2010 to form the BRICS. This July, ...
    • Should the Security Council Engage with Implications of Climate Change? Let’s Look at the Scientific Evidence 

      Buhaug, Halvard; Coning, Cedric de; von Uexkull, Nina (Chronicle; Kronikk, 2023-06-08)
      Climate change is a controversial topic at the United Nations (UN) Security Council. The Council has adopted over 70 resolutions and presidential statements that address aspects of climate-related peace and security implications. However, a few members strongly oppose adding climate change to the Security Council agenda. When a thematic resolution on the security implications of climate change came ...
    • Lipid Levels During Adult Lifetime in Men and Women With and Without a Subsequent Incident Myocardial Infarction: A Longitudinal Analysis of Data From the Tromsø Study 1974 to 2016 

      Albrektsen, Grethe; Wilsgaard, Tom; Heuch, Ivar; Løchen, Maja-Lisa; Thelle, Dag Steinar; Njølstad, Inger; Grimsgaard, Sameline; Bønaa, Kaare Harald (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-14)
      Background - The atherosclerotic effect of an adverse lipid profile is assumed to accumulate throughout life, leading to increased risk of myocardial infarction (MI). Still, little is known about age at onset and duration of unfavorable lipid levels before MI.<p> <p>Methods and Results - Longitudinal data on serum lipid levels for 26 130 individuals (50.5% women, aged 20–89 years) were obtained ...
    • Percent of remaining life on palliative radiation treatment: solely a function of fractionation? 

      Nieder, Carsten; Mannsåker, Bård; Dalhaug, Astrid (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-02-14)
      Background: This study analyzed the percent of remaining life (PRL) on treatment in patients irradiated for bone metastases. Bone metastases were treated together with other target volumes, if indicated, e.g. a 10-fraction treatment course that included brain and bone metastases. PRL was determined by calculating the time between start and finish of palliative radiotherapy (minimum 1 day in case of ...