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Overexpression of miR-20a-5p in Tumor Epithelium Is an Independent Negative Prognostic Indicator in Prostate Cancer — A Multi-Institutional Study
(Master thesis; Mastergradsoppgave; Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-26)<p><i>Background:</i> MicroRNAs (miRs) have critical regulatory roles in cell functions, and are involved in prostate cancer tumorigenesis. miR-20a-5p is a member of the oncogenic miR-17-92 cluster. Overexpressed miR-20a-5p has been shown to increase both cell proliferation and cell migration in cancers. The aim of our cohort study was to evaluate the prognostic role of miR-20a-5p in prostate cancer. ... -
Mobile app as a tool to collect health data: a survey on vaccination against COVID-19
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022)Objective. To evaluate the feasibility of using a mobile app to collect health-related data and the impact of this data collection method on the results obtained, using the COVID-19 vaccination attitude assessment as an example. Material and methods. A survey was conducted on attitudes towards COVID-19 vaccination using the «Know Your Heart» mobile app. A total of 1,770 Arkhangelsk region residents ... -
Regression-based norms for the FAS phonemic fluency test for ages 40–84 based on a Norwegian sample
(Mastergradsoppgave; Master thesis, 2023-01-06)The FAS phonemic fluency test is a commonly used neuropsychological test of executive function and processing speed. Although Norwegian discrete norms have been developed for the FAS test, American regression-based norms are frequently used by clinicians in Norway. However, language and cultural differences impact performance on the FAS test, and using foreign norms may not be appropriate. Moreover, ... -
Cross-Ancestry Investigation of Venous Thromboembolism Genomic Predictors
(Journal article; Tidsskriftartikkel, 2022)<p><i>Background:</i> Venous thromboembolism (VTE) is a life-threatening vascular event with environmental and genetic determinants. Recent VTE genome-wide association studies (GWAS) meta-analyses involved nearly 30 000 VTE cases and identified up to 40 genetic loci associated with VTE risk, including loci not previously suspected to play a role in hemostasis. The aim of our research was to expand ... -
Hans Ellegren, Hvad nytt och nyttigt: Tillkomsten av landets första lärda sällskap: Kungl. Vetenskaps-Societeten i Uppsala & En akademi finner sin väg (Uppsala: Kungl. Vetenskaps-Societeten, 2019 & 2020). 306 + 337 s.
(Journal article; Tidsskriftartikkel, 2022-12-29)<p>På 1700-tallet var det to kongelige vitenskapelige foreninger i sving i Sverige. Den første ble dannet i Uppsala, hvor den sprang ut av kirken (erkebiskopens sønn) og professorsjiktet ved universitetet. Publiseringsspråket var latin. Den andre foreningen, Kungl. Vetenskapsakademien, var et barn av hovedstadens allianse mellom hoffkultur, opplysning og merkantilisme. Publiseringsspråket var svensk. ... -
Factors associated with treatment satisfaction in patients with hidradenitis suppurativa: results from the Global VOICE project
(Journal article; Tidsskriftartikkel, 2022-12-01)<p><i>Background</i> Nearly half of patients with hidradenitis suppurativa (HS) report dissatisfaction with their treatment. However, factors related to treatment satisfaction have not been explored. <p><i>Objectives</i> To measure associations between treatment satisfaction and clinical and treatment‐related characteristics among patients with HS. <p><i>Methods</i> Treatment satisfaction was ... -
The conflicting effects of self-construal on impulsive buying tendency toward unhealthy food: the moderating role of future time perspective
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-03)This study extends the understanding of if and how consumer impulse buying tendency toward unhealthy food can be explained by the conflicting and interactive mechanisms of individual differences in self-construal and future time perspectives. Based on a survey sample of 439 Vietnamese consumers, this study adopts a structural equation modelling approach for second-order constructs and moderating ... -
Association of lipid-lowering drugs and antidiabetic drugs with age-related macular degeneration: A meta-analysis in Europeans
(Journal article; Tidsskriftartikkel, 2022-11-07)<p><i>Background/aims</i> To investigate the association of commonly used systemic medications with prevalent age-related macular degeneration (AMD) in the general population. <p><i>Methods</i> We included 38 694 adults from 14 population-based and hospital-based studies from the European Eye Epidemiology consortium. We examined associations between the use of systemic medications and any prevalent ... -
Global patterns and drivers of ecosystem functioning in rivers and riparian zones
(Journal article; Tidsskriftartikkel; Peer reviewed, 2019-01-09)River ecosystems receive and process vast quantities of terrestrial organic carbon, the fate of which depends strongly on microbial activity. Variation in and controls of processing rates, however, are poorly characterized at the global scale. In response, we used a peer-sourced research network and a highly standardized carbon processing assay to conduct a global-scale field experiment in greater ... -
Chronological changes in soil biogeochemical properties of the glacier foreland of Midtre Lovénbreen, Svalbard, attributed to soil-forming factors
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-02-21)Glacier forelands provide an excellent opportunity to investigate vegetation succession and soil development along the chronosequence; however, there are few studies on soil biogeochemical changes from environmental factors, aside from time. This study aimed to investigate soil development and biogeochemical changes in the glacier foreland of Midtre Lov ́enbreen, Svalbard, by considering various ... -
Peptides from the Sea Anemone Metridium senile with Modified Inhibitor Cystine Knot (ICK) Fold Inhibit Nicotinic Acetylcholine Receptors
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-30)Nicotinic acetylcholine receptors (nAChRs) play an important role in the functioning of the central and peripheral nervous systems, and other organs of living creatures. There are several subtypes of nAChRs, and almost all of them are considered as pharmacological targets in different pathological states. The crude venom of the sea anemone Metridium senile showed the ability to interact with ... -
Note to first-year university students: Just do it! In the end, the fact that you study may be more important than how you study.
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-20)Education is important to society, yet many students do not complete the educations they start. In the present study of 426 students at a Norwegian university, we examined the predictive value of study-related variables with regard to student status one and five years after initial enrollment (stayers versus dropouts). The logistic regression analyses indicated that older students and students who ... -
Investigation of ice accretion effect on the aerodynamic characteristics of a wind turbine blade tip after a short icing event
(Conference object; Konferansebidrag, 2022-01)The paper investigates the flow behavior near the NACA 64-618 airfoil profile of the blade tip section of a wind turbine for electric power production after a short icing event. The flow simulation considering the rotation speed of the wind turbine blade is performed to assess the effect of icing on the aerodynamic characteristics. Degradation of aerodynamic characteristics affects the electrical ... -
Collecting health-related research data using consumer-based wireless smart scales
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-14)Background: Serious public-health concerns such as overweight and obesity are in many cases caused by excess intake of food combined with decreases in physical activity. Smart scales with wireless data transfer can, together with smart watches and trackers, observe changes in the population’s health. They can present us with a picture of our metabolism, body health, and disease risks. Combining ... -
Computing critical points for invariant algebraic systems
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-24) -
Neuroendocrinology of sexual behavior
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-12-08)One of the consequences of sexual behavior is reproduction. Thus, this behavior is essential for the survival of the species. However, the individual engaged in sexual behavior is rarely aware of its reproductive consequences. In fact, the human is probably the only species in which sexual acts may be performed with the explicit purpose of reproduction. Most human sexual activities as well as sex ... -
Fødselsrift – hva så? Kvinners vurdering av informasjon om fødselsrift mottatt på barselavdelingen, oppfølgingen de mottar, og betydningen av informasjonen for bekymringer, utfordringer og mestring av fødselsriften de første seks måneder etter fødsel
(Master thesis; Mastergradsoppgave, 2022-03-16)Bakgrunn: Kvinner som rammes av en fødselsrift kan ha et udekt informasjonsbehov. Mangel på informasjon kan føre til utfordringer relatert til fysisk og psykisk helse, uavhengig av hvilken grad av rift som er ervervet. Hensikt: Hensikten med studien var å kartlegge kvinners vurdering av informasjonen mottatt om sin fødselsrift på barselavdelingen, erfaringen med oppfølgingen fra helsevesenet ... -
Late Holocene pteropod distribution across the base of the south-eastern Mediterranean margin: the importance of the > 63 µm fraction
(Journal article; Tidsskriftartikkel; Peer reviewed, 2023-03-17)Euthecosomata pteropods were analysed in core sediments collected in the framework of the 2016 EUROFLEETS2 SEMSEEP cruise, offshore of Israel, in the eastern Mediterranean Sea. The investigated cores were retrieved in a deep-sea coral area at 690 m depth, an actively methane-seeping pockmark area at 1038 m depth, and a deep-sea channel area at 1310 m water depth. We identified and documented the ... -
Why Libraries Matter in the New Diplomacy Era?
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-10-31)Libraries, museums, and cultural centers have long been widely advocated for diplomacy as an enabler for knowledge sharing, cultural exchange, and scientific cooperation, advancing people-to-people ties and mutual understanding in the international system (Mariano and Vårheim, 2021). In spite of the contribution of libraries as a public sphere institution (Vårheim, Skare, and Lenstra, 2019), a ... -
Serum amyloid A1 and pregnancy zone protein in pregnancy complications and correlation with markers of placental dysfunction
(Journal article; Tidsskriftartikkel; Peer reviewed, 2022-11-09)BACKGROUND: Hypertensive disorders of pregnancy (preeclampsia, gestational hypertension, and chronic hypertension), diabetes mellitus, and placental dysfunction confer an increased risk of long-term maternal cardiovascular disease. Preeclampsia is also associated with acute atherosis that involves lesions of uteroplacental spiral arteries, resembling early stages of atherosclerosis. Serum amyloid ...
