Blar i forfatter Artikler, rapporter og annet (kjemi) "Carlsen, Trine Josefine Warg"

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    • Biochemical and biophysical characterization of the OXA-48-like carbapenemase OXA-436 

      Lund, Bjarte Aarmo; Thomassen, Ane Molden; Carlsen, Trine Josefine Warg; Leiros, Hanna-Kirsti Schrøder (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-08-31)
      The crystal structure of the class D β-lactamase OXA-436 was solved to a resolution of 1.80 Å. Higher catalytic rates were found at higher temperatures for the clinically important antibiotic imipenem, indicating better adaptation of OXA-436 to its mesophilic host than OXA-48, which is believed to originate from an environmental source. Furthermore, based on the most populated conformations during ...