Blar i forfatter Artikler, rapporter og annet (kjemi) "Cavanagh, Jorunn Pauline"

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    • Bacterial extracellular vesicles: towards realistic models for bacterial membranes in molecular interaction studies by surface plasmon resonance 

      Brilkov, Maxim; Stenbakk, Victoria; Jakubec, Martin; Vasskog, Terje; Kristoffersen, Tone; Cavanagh, Jorunn Pauline; Ericson, Johanna Ulrica; Isaksson, Johan Mattias; Flaten, Gøril Eide (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-12-13)
      One way to mitigate the ongoing antimicrobial resistance crisis is to discover and develop new classes of antibiotics. As all antibiotics at some point need to either cross or just interact with the bacterial membrane, there is a need for representative models of bacterial membranes and efficient methods to characterize the interactions with novel molecules -both to generate new knowledge and to ...

    • Effects of fecal microbiota transplantation in subjects with irritable bowel syndrome are mirrored by changes in gut microbiome 

      Goll, Rasmus; Johnsen, Peter Holger; Hjerde, Erik; Diab, Joseph; Valle, Per Christian; Hilpüsch, Frank; Cavanagh, Jorunn Pauline (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-09-29)
      Irritable bowel syndrome (IBS) is a common disorder of the lower gastrointestinal tract. The pathophysiology is far from settled, but a gut microbial dysbiosis is hypothesized to be a contributing factor. We earlier published a randomized double-blind placebo-controlled clinical trial on fecal microbiota transplantation (FMT) for IBS – the REFIT trial. The present data set describes the engraftment ...

    • Lactoferricin-inspired peptide AMC-109 augments the effect of ciprofloxacin against Pseudomonas aeruginosa biofilm in chronic murine wounds 

      Laulund, Anne Sofie; Schwartz, Franziska Angelika; Christophersen, Lars; Høiby, Niels; Svendsen, John Sigurd Mjøen; Stensen, Wenche Gunvor Berg; Thomsen, Kim; Cavanagh, Jorunn Pauline; Moser, Claus (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-12-23)
      Objectives: Chronic wounds are characterised by prolonged inflammation, low mitogenic activity, high protease/low inhibitor activity, microbiota changes and biofilm formation, combined with the aetiology of the original insult. One strategy to promote healing is to terminate the parasitism-like relationship between the biofilm-growing pathogen and host response. Antimicrobial peptide AMC-109 is a ...