Blar i forfatter Artikler, rapporter og annet (kjemi) "Day, Craig S."

Viser treff 1-2 av 2

    • Efficient palladium-catalyzed electrocarboxylation enables late-stage carbon isotope labelling 

      Batista, Gabriel M. F.; Ebenbauer, Ruth; Day, Craig S.; Bergare, Jonas; Neumann, Karoline; Hopmann, Kathrin Helen; Elmore, Charles; Rosas-Hernandez, Alonso; Skrydstrup, Troels (Journal article; Tidsskriftartikkel; Peer reviewed, 2024-03-22)
      Carbon isotope labelling of bioactive molecules is essential for accessing the pharmacokinetic and pharmacodynamic properties of new drug entities. Aryl carboxylic acids represent an important class of structural motifs ubiquitous in pharmaceutically active molecules and are ideal targets for the installation of a radioactive tag employing isotopically labelled CO<sub>2</sub>. However, direct isotope ...

    • Room Temperature-Stable Magnesium Electride via Ni(II) Reduction 

      Do, Cuong Dat; Day, Craig S.; Odena, Carlota; Benet-Buchholz, Jordi; Xu, Liang; Foroutan-Nejad, Cina; Hopmann, Kathrin Helen; Martin, Ruben (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-07-13)
      Herein, we report the synthesis of highly reduced bipyridyl magnesium complexes and the first example of a stable organic magnesium electride supported by quantum mechanical computations and X-ray diffraction. These complexes serve as unconventional homogeneous reductants due to their high solubility, modular redox potentials, and formation of insoluble, non-coordinating byproducts. The applicability ...